Search Results - "Chung, Doo Hyun"

Invariant natural killer T cells in lung diseases by Jeong, Dongjin, Woo, Yeon Duk, Chung, Doo Hyun

“…Invariant natural killer T ( i NKT) cells are a subset of T cells that are characterized by a restricted T-cell receptor (TCR) repertoire and a unique ability…”
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Immune Networks in Health and Disease by Lee, Heung Kyu, Chung, Doo Hyun

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Predictive and Prognostic Impact of Epidermal Growth Factor Receptor Mutation in Non–Small-Cell Lung Cancer Patients Treated With Gefitinib by HAN, Sae-Won, KIM, Tae-You, IM, Seock-Ah, YOUNG TAE KIM, JONG SEOK LEE, DAE SEOG HEO, BANG, Yung-Jue, NOE KYEONG KIM, PIL GYU HWANG, JEONG, Soohyun, KIM, Jeongmi, IN SIL CHOI, OH, Do-Youn, JEE HYUN KIM, KIM, Dong-Wan, DOO HYUN CHUNG

“…This study was undertaken to investigate the effects of epidermal growth factor receptor (EGFR) mutation and its downstream signaling on response and survival…”
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Development and Functions of Alveolar Macrophages by Woo, Yeon Duk, Jeong, Dongjin, Chung, Doo Hyun

“…Macrophages residing in various tissue types are unique in terms of their anatomical locations, ontogenies, developmental pathways, gene expression patterns,…”
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Optimization of Patient Selection for Gefitinib in Non–Small Cell Lung Cancer by Combined Analysis of Epidermal Growth Factor Receptor Mutation, K-ras Mutation, and Akt Phosphorylation by Han, Sae-Won, Kim, Tae-You, Jeon, Yoon Kyung, Hwang, Pil Gyu, Im, Seock-Ah, Lee, Kyung-Hun, Kim, Jee Hyun, Kim, Dong-Wan, Heo, Dae Seog, Kim, Noe Kyeong, Chung, Doo Hyun, Bang, Yung-Jue

“…Purpose: Mutations in epidermal growth factor receptor (EGFR) are strongly predictive of gefitinib efficacy in non–small-cell lung cancer. However, the…”
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Adequacy Criteria of Rapid On-Site Evaluation for Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: A Simple Algorithm to Assess the Adequacy of ROSE by Choi, Sun Mi, MD, Lee, Ae-Ra, MD, Choe, Ji-Young, MD, Nam, Soo Jeong, MD, PhD, Chung, Doo Hyun, MD, PhD, Lee, Jinwoo, MD, Lee, Chang-Hoon, MD, PhD, Lee, Sang-Min, MD, PhD, Yim, Jae-Joon, MD, PhD, Yoo, Chul-Gyu, MD, PhD, Kim, Young Whan, MD, PhD, Han, Sung Koo, Park, Young Sik, MD

“…Background Rapid on-site evaluation (ROSE) for endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been advocated to qualitatively…”
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Mesenchymal Stem Cells Suppress Severe Asthma by Directly Regulating Th2 Cells and Type 2 Innate Lymphoid Cells by Shin, Jae Woo, Ryu, Seungwon, Ham, Jongho, Jung, Keehoon, Lee, Sangho, Chung, Doo Hyun, Kang, Hye-Ryun, Kim, Hye Young

“…Patients with severe asthma have unmet clinical needs for effective and safe therapies. One possibility may be mesenchymal stem cell (MSC) therapy, which can…”
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Epidermal growth factor receptor (EGFR) downstream molecules as response predictive markers for gefitinib (Iressa®, ZD1839) in chemotherapy‐resistant non‐small cell lung cancer by Han, Sae‐Won, Hwang, Pil Gyu, Chung, Doo Hyun, Kim, Dong‐Wan, Im, Seock‐Ah, Kim, Young Tae, Kim, Tae‐You, Heo, Dae Seog, Bang, Yung‐Jue, Kim, Noe Kyeong

“…Gefitinib has shown meaningful antitumor activity with tolerable toxicity in chemotherapy‐refractory NSCLC in previous studies. Moreover, EGFR expression…”
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Programmed death-1 ligand 1 and 2 are highly expressed in pleomorphic carcinomas of the lung: Comparison of sarcomatous and carcinomatous areas by Kim, Sehui, Kim, Moon-Young, Koh, Jaemoon, Go, Heounjeong, Lee, Dong Soo, Jeon, Yoon Kyung, Chung, Doo Hyun

“…Highlights • We evaluate the PD-1/PD-Ls pathway molecules in pulmonary pleomorphic carcinoma (PC). • PD-L1 and PD-L2 are highly expressed in pulmonary PCs. •…”
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Tracing Oncogene Rearrangements in the Mutational History of Lung Adenocarcinoma by Lee, Jake June-Koo, Park, Seongyeol, Park, Hansol, Kim, Sehui, Lee, Jongkeun, Lee, Junehawk, Youk, Jeonghwan, Yi, Kijong, An, Yohan, Park, In Kyu, Kang, Chang Hyun, Chung, Doo Hyun, Kim, Tae Min, Jeon, Yoon Kyung, Hong, Dongwan, Park, Peter J., Ju, Young Seok, Kim, Young Tae

“…Mutational processes giving rise to lung adenocarcinomas (LADCs) in non-smokers remain elusive. We analyzed 138 LADC whole genomes, including 83 cases with…”
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Psat1-Dependent Fluctuations in α-Ketoglutarate Affect the Timing of ESC Differentiation by Hwang, In-Young, Kwak, Sojung, Lee, Sangho, Kim, Hyunsoo, Lee, Sang Eun, Kim, Jae-Hwan, Kim, Young Ah, Jeon, Yoon Kyung, Chung, Doo Hyun, Jin, Xing, Park, Sunghyouk, Jang, Hyonchol, Cho, Eun-Jung, Youn, Hong-Duk

“…Embryonic stem cells (ESCs) undergo coordinated epigenetic and metabolic changes to differentiate properly. However, the precise mechanisms by which these…”
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Comparative analysis of PD-L1 expression between primary and metastatic pulmonary adenocarcinomas by Kim, Sehui, Koh, Jaemoon, Kwon, Dohee, Keam, Bhumsuk, Go, Heounjeong, Kim, Young A, Jeon, Yoon Kyung, Chung, Doo Hyun

“…Abstract Programmed death-ligand 1 (PD-L1) expression in pulmonary adenocarcinomas (pADCs) was implicated in predicting anti-PD-1/PD-L1 therapy efficacy…”
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Innate immune crosstalk in asthmatic airways: Innate lymphoid cells coordinate polarization of lung macrophages by Kim, Jihyun, Chang, Yuna, Bae, Boram, Sohn, Kyoung-Hee, Cho, Sang-Heon, Chung, Doo Hyun, Kang, Hye Ryun, Kim, Hye Young

“…Recent studies have emphasized the role of innate lymphoid cells (ILCs) in the development of asthma. The involvement of group 2 innate lymphoid cells (ILC2s)…”
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Tumor Suppressor miRNA-204-5p Regulates Growth, Metastasis, and Immune Microenvironment Remodeling in Breast Cancer by Hong, Bok Sil, Ryu, Han Suk, Kim, Namshin, Kim, Jisun, Lee, Eunshin, Moon, Hyunhye, Kim, Kyoung Hyoun, Jin, Min-Sun, Kwon, Nam Hoon, Kim, Sunghoon, Kim, Donghyun, Chung, Doo Hyun, Jeong, Kyeonghun, Kim, Kwangsoo, Kim, Ki Yoon, Lee, Han-Byoel, Han, Wonshik, Yun, Jihui, Kim, Jong-Il, Noh, Dong-Young, Moon, Hyeong-Gon

“…Various miRNAs play critical roles in the development and progression of solid tumors. In this study, we describe the role of miR-204-5p in limiting growth and…”
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PD-L1 expression is associated with epithelial-to-mesenchymal transition in adenocarcinoma of the lung by Kim, Sehui, MD, Koh, Jaemoon, MD, Kim, Moon-Young, MD, Kwon, Dohee, MD, Go, Heounjeong, MD, PhD, Kim, Young A., MD, PhD, Jeon, Yoon Kyung, MD, PhD, Chung, Doo Hyun, MD, PhD

“…PD-1/PD-L1-targeted immunotherapy has emerged as a promising therapeutic strategy for pulmonary adenocarcinoma (pADC). Epithelial-to-mesenchymal transition…”
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Correlation between the size of the solid component on thin-section CT and the invasive component on pathology in small lung adenocarcinomas manifesting as ground-glass nodules by Lee, Kyung Hee, Goo, Jin Mo, Park, Sang Joon, Wi, Jae Yeon, Chung, Doo Hyun, Go, Heounjeong, Park, Heae Surng, Park, Chang Min, Lee, Sang Min

“…We aimed to evaluate the correlation between the size of the solid component on thin-section computed tomography (CT) and invasive component on pathology in…”
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Differences in tumor microenvironments between primary lung tumors and brain metastases in lung cancer patients: therapeutic implications for immune checkpoint inhibitors by Kim, Ryul, Keam, Bhumsuk, Kim, Sehui, Kim, Miso, Kim, Se Hyun, Kim, Jin Wook, Kim, Yu Jung, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Lee, Jong Seok, Heo, Dae Seog

“…We aimed to compare intra- and extracranial responses to immune checkpoint inhibitors (ICIs) in lung cancer with brain metastases (BM), and to explore tumor…”
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Prognostic implications of intratumoral CD103+ tumor-infiltrating lymphocytes in pulmonary squamous cell carcinoma by Koh, Jaemoon, Kim, Sehui, Kim, Moon-Young, Go, Heounjeong, Jeon, Yoon Kyung, Chung, Doo Hyun

“…CD103 is the αE subunit of αEβ7 integrin that is expressed in tissue-resident memory T cells, where it promotes cytotoxic T cell responses against tumors…”
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Mesenchymal Stem Cells Suppress Severe Asthma by Directly Regulating Th2 Cells and Type 2 Innate Lymphoid Cells by Shin, Jae Woo, Ryu, Seungwon, Ham, Jongho, Jung, Keehoon, Lee, Sangho, Chung, Doo Hyun, Kang, Hye-Ryun, Kim, Hye Young

“…Patients with severe asthma have unmet clinical needs for effective and safe therapies. One possibility may be mesenchymal stem cell (MSC) therapy, which can…”
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Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency by Kim, Hyunsoo, Jang, Hyonchol, Kim, Tae Wan, Kang, Byung‐Hee, Lee, Sang Eun, Jeon, Yoon Kyung, Chung, Doo Hyun, Choi, Jinmi, Shin, Jihoon, Cho, Eun‐Jung, Youn, Hong‐Duk

“…Pluripotent stem cells (PSCs) have distinct metabolic properties that support their metabolic and energetic needs and affect their stemness. In particular,…”
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