Search Results - "Chung, Daniel"

Pathways of Colorectal Carcinogenesis by Nguyen, Long H., Goel, Ajay, Chung, Daniel C.

“…Colorectal cancer is a heterogeneous disease that develops via stepwise accumulation of well-characterized genetic and epigenetic alterations. We review the…”
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The Chromosomal Instability Pathway in Colon Cancer by Pino, Maria S, Chung, Daniel C

“…The acquisition of genomic instability is a crucial feature in tumor development and there are at least 3 distinct pathways in colorectal cancer pathogenesis:…”
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Gravitational production of super-Hubble-mass particles: an analytic approach by Chung, Daniel J. H., Kolb, Edward W., Long, Andrew J.

“…A bstract Through a mechanism similar to perturbative particle scattering, particles of mass m χ larger than the Hubble expansion rate H inf during inflation…”
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Quantum interference in gravitational particle production by Basso, Edward, Chung, Daniel J. H., Kolb, Edward W., Long, Andrew J.

“…A bstract Previous numerical investigations of gravitational particle production during the coherent oscillation period of inflation displayed unexplained…”
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Predicting the Drag of Rough Surfaces by Chung, Daniel, Hutchins, Nicholas, Schultz, Michael P, Flack, Karen A

“…Reliable full-scale prediction of drag due to rough wall-bounded turbulent fluid flow remains a challenge. Currently, the uncertainty is at least 10%, with…”
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Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial by Lyon, Paul C, Gray, Michael D, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C

“…Previous preclinical research has shown that extracorporeal devices can be used to enhance the delivery and distribution of systemically administered…”
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Computation of gravitational particle production using adiabatic invariants by Basso, Edward E., Chung, Daniel J. H.

“…A bstract Analytic and numerical techniques are presented for computing gravitational production of scalar particles in the limit that the inflaton mass is…”
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Trends in use of prescription stimulants in the United States and Territories, 2006 to 2016 by Piper, Brian J, Ogden, Christy L, Simoyan, Olapeju M, Chung, Daniel Y, Caggiano, James F, Nichols, Stephanie D, McCall, Kenneth L

“…Stimulants are considered the first-line treatment for Attention Deficit Hyperactivity Disorder (ADHD) in the US and they are used in other indications…”
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Pathological Basis for Deficient Excitatory Drive to Cortical Parvalbumin Interneurons in Schizophrenia by Chung, Daniel W, Fish, Kenneth N, Lewis, David A

“…Objective:Deficient excitatory drive to parvalbumin-containing cortical interneurons is proposed as a key neural substrate for altered gamma oscillations and…”
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Genetic Testing and Early Onset Colon Cancer by Chung, Daniel C.

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Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment by Kostic, Aleksandar D., Chun, Eunyoung, Robertson, Lauren, Glickman, Jonathan N., Gallini, Carey Ann, Michaud, Monia, Clancy, Thomas E., Chung, Daniel C., Lochhead, Paul, Hold, Georgina L., El-Omar, Emad M., Brenner, Dean, Fuchs, Charles S., Meyerson, Matthew, Garrett, Wendy S.

“…Increasing evidence links the gut microbiota with colorectal cancer. Metagenomic analyses indicate that symbiotic Fusobacterium spp. are associated with human…”
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Perinuclear tethers license telomeric DSBs for a broad kinesin- and NPC-dependent DNA repair process by Chung, Daniel K.C., Chan, Janet N.Y., Strecker, Jonathan, Zhang, Wei, Ebrahimi-Ardebili, Sasha, Lu, Thomas, Abraham, Karan J., Durocher, Daniel, Mekhail, Karim

“…DNA double-strand breaks (DSBs) are often targeted to nuclear pore complexes (NPCs) for repair. How targeting is achieved and the DNA repair pathways involved…”
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Gravitational fermion production in inflationary cosmology by Chung, Daniel J.H., Everett, Lisa L., Yoo, Hojin, Zhou, Peng

“…We revisit the gravitational production of massive Dirac fermions in inflationary cosmology with a focus on clarifying the analytic computation of the particle…”
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Extinction in a hyperdiverse endemic Hawaiian land snail family and implications for the underestimation of invertebrate extinction by Régnier, Claire, Bouchet, Philippe, Hayes, Kenneth A, Yeung, Norine W, Christensen, Carl C, Chung, Daniel J. D, Fontaine, Benoît, Cowie, Robert H

“…The International Union for Conservation of Nature (IUCN) Red List includes 832 species listed as extinct since 1600, a minuscule fraction of total…”
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Nuclear microtubule filaments mediate non-linear directional motion of chromatin and promote DNA repair by Oshidari, Roxanne, Strecker, Jonathan, Chung, Daniel K. C., Abraham, Karan J., Chan, Janet N. Y., Damaren, Christopher J., Mekhail, Karim

“…Damaged DNA shows increased mobility, which can promote interactions with repair-conducive nuclear pore complexes (NPCs). This apparently random mobility is…”
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Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial by Gray, Michael D, Lyon, Paul C, Mannaris, Christophoros, Folkes, Lisa K, Stratford, Michael, Campo, Leticia, Chung, Daniel Y F, Scott, Shaun, Anderson, Mark, Goldin, Robert, Carlisle, Robert, Wu, Feng, Middleton, Mark R, Gleeson, Fergus V, Coussios, Constantin C

“…Purpose To demonstrate the feasibility and safety of using focused ultrasound planning models to determine the treatment parameters needed to deliver…”
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Efficacy, Safety, and Durability of Voretigene Neparvovec-rzyl in RPE65 Mutation-Associated Inherited Retinal Dystrophy: Results of Phase 1 and 3 Trials by Maguire, Albert M, Russell, Stephen, Wellman, Jennifer A, Chung, Daniel C, Yu, Zi-Fan, Tillman, Amy, Wittes, Janet, Pappas, Julie, Elci, Okan, Marshall, Kathleen A, McCague, Sarah, Reichert, Hannah, Davis, Maria, Simonelli, Francesca, Leroy, Bart P, Wright, J Fraser, High, Katherine A, Bennett, Jean

“…To report the durability of voretigene neparvovec-rzyl (VN) adeno-associated viral vector-based gene therapy for RPE65 mutation-associated inherited retinal…”
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Synaptic Variability and Cortical Gamma Oscillation Power in Schizophrenia by Chung, Daniel W, Geramita, Matthew A, Lewis, David A

“…Cognitive impairments in schizophrenia are associated with lower gamma oscillation power in the prefrontal cortex (PFC). Gamma power depends in part on…”
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Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial by Russell, Stephen, Bennett, Jean, Wellman, Jennifer A, Chung, Daniel C, Yu, Zi-Fan, Tillman, Amy, Wittes, Janet, Pappas, Julie, Elci, Okan, McCague, Sarah, Cross, Dominique, Marshall, Kathleen A, Walshire, Jean, Kehoe, Taylor L, Reichert, Hannah, Davis, Maria, Raffini, Leslie, George, Lindsey A, Hudson, F Parker, Dingfield, Laura, Zhu, Xiaosong, Haller, Julia A, Sohn, Elliott H, Mahajan, Vinit B, Pfeifer, Wanda, Weckmann, Michelle, Johnson, Chris, Gewaily, Dina, Drack, Arlene, Stone, Edwin, Wachtel, Katie, Simonelli, Francesca, Leroy, Bart P, Wright, J Fraser, High, Katherine A, Maguire, Albert M

“…Phase 1 studies have shown potential benefit of gene replacement in RPE65-mediated inherited retinal dystrophy. This phase 3 study assessed the efficacy and…”
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An energy-efficient pathway to turbulent drag reduction by Marusic, Ivan, Chandran, Dileep, Rouhi, Amirreza, Fu, Matt K., Wine, David, Holloway, Brian, Chung, Daniel, Smits, Alexander J.

“…Simulations and experiments at low Reynolds numbers have suggested that skin-friction drag generated by turbulent fluid flow over a surface can be decreased by…”
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