Search Results - "Chung, Cheng‐Chih"

Empagliflozin Attenuates Myocardial Sodium and Calcium Dysregulation and Reverses Cardiac Remodeling in Streptozotocin-Induced Diabetic Rats by Lee, Ting-I, Chen, Yao-Chang, Lin, Yung-Kuo, Chung, Cheng-Chih, Lu, Yen-Yu, Kao, Yu-Hsun, Chen, Yi-Jen

“…Diabetes mellitus (DM) has significant effects on cardiac calcium (Ca ) and sodium (Na⁺) regulation. Clinical studies have shown that empagliflozin…”
Get full text

Lithium Treatment Improves Cardiac Dysfunction in Rats Deprived of Rapid Eye Movement Sleep by Chen, Pao-Huan, Chung, Cheng-Chih, Liu, Shuen-Hsin, Kao, Yu-Hsun, Chen, Yi-Jen

“…Rapid eye movement (REM) sleep deprivation triggers mania and induces cardiac fibrosis. Beyond neuroprotection, lithium has cardioprotective potential and…”
Get full text

Fibroblast Growth Factor 23 Stimulates Cardiac Fibroblast Activity through Phospholipase C-Mediated Calcium Signaling by Lee, Ting-Wei, Chung, Cheng-Chih, Lee, Ting-I, Lin, Yung-Kuo, Kao, Yu-Hsun, Chen, Yi-Jen

“…Fibroblast growth factor (FGF)-23 induces hypertrophy and calcium (Ca ) dysregulation in cardiomyocytes, leading to cardiac arrhythmia and heart failure…”
Get full text

Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis by Chung, Cheng-Chih, Lin, Yung-Kuo, Chen, Yao-Chang, Kao, Yu-Hsun, Yeh, Yung-Hsin, Trang, Nguyen Ngoc, Chen, Yi-Jen

“…The novel sodium-glucose co-transporter 2 inhibitor (SGLT2i) potentially ameliorates heart failure and reduces cardiac arrhythmia. Cardiac fibrosis plays a…”
Get full text

Class I HDAC modulates angiotensin II–induced fibroblast migration and mitochondrial overactivity by Huynh, Tin Van, Rethi, Lekha, Chung, Cheng‐Chih, Yeh, Yung‐Hsin, Kao, Yu‐Hsun, Chen, Yi‐Jen

“…Background Inhibition of histone deacetylases (HDACs) attenuates cardiac fibrosis. In this study, we evaluated whether the inhibition of class I HDACs can…”
Get full text

Vascular endothelial growth factor enhances profibrotic activities through modulation of calcium homeostasis in human atrial fibroblasts by Chung, Cheng-Chih, Lin, Yung-Kuo, Chen, Yao-Chang, Kao, Yu-Hsun, Lee, Ting-I, Chen, Yi-Jen

“…Vascular endothelial growth factor (VEGF), a pivotal activator of angiogenesis and calcium (Ca2+) signaling in endothelial cells, was shown to increase…”
Get full text

Physiological testosterone attenuates profibrotic activities of rat cardiac fibroblasts through modulation of nitric oxide and calcium homeostasis by Chung, Cheng-Chih, Lin, Yung-Kuo, Kao, Yu-Hsun, Lin, Shyh-Hsiang, Chen, Yi-Jen

“…Testosterone deficiency is associated with poor prognosis among patients with chronic heart failure (HF). Physiological testosterone improves the exercise…”
Get full text

Galectin‐3 enhances atrial remodelling and arrhythmogenesis through CD98 signalling by Cheng, Wan‐Li, Chen, Yao‐Chang, Li, Shao‐Jung, Lee, Ting‐I, Lee, Ting‐Wei, Higa, Satoshi, Chung, Cheng‐Chih, Kao, Yu‐Hsun, Chen, Shih‐Ann, Chen, Yi‐Jen

“…Aim Galectin‐3 (Gal‐3) is a biomarker of atrial fibrillation (AF) that mediates atrial inflammation. CD98 is the membrane surface receptor for Gal‐3…”
Get full text

Empagliflozin and Liraglutide Differentially Modulate Cardiac Metabolism in Diabetic Cardiomyopathy in Rats by Trang, Nguyen Ngoc, Chung, Cheng-Chih, Lee, Ting-Wei, Cheng, Wan-Li, Kao, Yu-Hsun, Huang, Shih-Yu, Lee, Ting-I, Chen, Yi-Jen

“…Glucagon-like peptide 1 receptor agonists (GLP-1RAs) and sodium-glucose cotransporter-2 inhibitors (SGLT2is) are antihyperglycemic agents with cardioprotective…”
Get full text

Ceramide modulates electrophysiological characteristics and oxidative stress of pulmonary vein cardiomyocytes by Huang, Shih‐Yu, Lu, Yen‐Yu, Lin, Yung‐Kuo, Chen, Yao‐Chang, Chen, Yi‐Ann, Chung, Cheng‐Chih, Lin, Wei‐Shiang, Chen, Shih‐Ann, Chen, Yi‐Jen

“…Background Ceramide is involved in regulating metabolism and energy expenditure, and its abnormal myocardial accumulation may contribute to heart injury or…”
Get full text

A Multimodel Framework for Quantifying Flow and Advective Transport Controlled by Earthquake-Induced Canister Failures in a Reference Case for Radioactive Waste Geological Disposal by Yu, Yun-Chen, Chen, Chi-Jen, Chung, Chih-Cheng, Ni, Chuen-Fa, Lee, I-Hsien, Wu, Yuan-Chieh, Lin, Tzu-Yu

“…Characterizing flow and transport for earthquake-induced shear canister failure is critical for the performance and safety assessment of radioactive waste…”
Get full text

Evaluation of the Effects of Window Films on the Indoor Environment and Air-Conditioning Electricity Consumption of Buildings by Huang, Hsing-Yun, Hu, Wei-Chieh, Chen, Chun-Kuei, Lin, Ta-Hui, Lin, Feng-Yi, Cheng, Chung-Chih, Su, Tzu-Ching, Yu, Pei-Yu

“…The objective of this study was to evaluate the effects of window films on indoor environmental conditions and electricity consumption of air conditioning. The…”
Get full text

Pitx2c inhibition increases atrial fibroblast activity: Implications in atrial arrhythmogenesis by Kao, Yu‐Hsun, Chung, Cheng‐Chih, Cheng, Wan‐Li, Lkhagva, Baigalmaa, Chen, Yi‐Jen

“…Background A Pitx2c deficiency increases the risk of atrial fibrillation (AF). Atrial structural remodelling with fibrosis blocks electrical conduction and…”
Get full text

Selective β2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis by Chin, Chih-Chien, Li, Jhy-Ming, Lee, Kam-Fai, Huang, Yun-Ching, Wang, Kuan-Chieh, Lai, Hsiao-Ching, Cheng, Chih-Chung, Kuo, Yi-Hung, Shi, Chung-Sheng

“…The stress‐upregulated catecholamines‐activated β1‐ and β2‐adrenergic receptors (β1/2‐ARs) have been shown to accelerate the progression of cancers such as…”
Get full text

Vascular endothelial growth factor on Runt‐related transcript factor‐2 in aortic valve cells by Li, Shao‐Jung, Kao, Yu‐Hsun, Chung, Cheng‐Chih, Cheng, Wan‐Li, Lin, Yung‐Kuo, Chen, Yi‐Jen

“…Background Calcific aortic valve disease is associated with ageing and high mortality. However, no effective pharmacological treatment has been developed…”
Get full text

Risk factors of chronic kidney disease in cisplatin-based hyperthermia intraperitoneal chemotherapy by Cheng, Chih-Chung, Yeh, Hung-Chieh, Su, Pei-Wen, Ho, Chien-Lin, Chang, Sheng-Chi

“…Cisplatin is commonly prescribed in hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal malignancy. Acute kidney injury (AKI) is regarded as a…”
Get full text

Sugar Fructose Triggers Gut Dysbiosis and Metabolic Inflammation with Cardiac Arrhythmogenesis by Cheng, Wan-Li, Li, Shao-Jung, Lee, Ting-I, Lee, Ting-Wei, Chung, Cheng-Chih, Kao, Yu-Hsun, Chen, Yi-Jen

“…Fructose is a main dietary sugar involved in the excess sugar intake-mediated progression of cardiovascular diseases and cardiac arrhythmias. Chronic intake of…”
Get full text

A Study on Control Strategy for Air Conditioning of Western Exposed Rooms in Subtropical Region by Hu, Tzu-Yang, Chen, Chun-Kuei, Hu, Wei-Chieh, Lin, Ta-Hui, Lin, Feng-Yi, Cheng, Chung-Chih, Su, Tzu-Ching, Yu, Pei-Yu

“…Recently, energy saving has been a major issue in all aspects. In buildings, air conditioning is one major part of power consumption. In this study, we…”
Get full text

Disturbed Cardiac Metabolism Triggers Atrial Arrhythmogenesis in Diabetes Mellitus: Energy Substrate Alternate as a Potential Therapeutic Intervention by Lkhagva, Baigalmaa, Lee, Ting-Wei, Lin, Yung-Kuo, Chen, Yao-Chang, Chung, Cheng-Chih, Higa, Satoshi, Chen, Yi-Jen

“…Atrial fibrillation (AF) is the most common type of sustained arrhythmia in diabetes mellitus (DM). Its morbidity and mortality rates are high, and its…”
Get full text

HDAC Inhibition Modulates Cardiac PPARs and Fatty Acid Metabolism in Diabetic Cardiomyopathy by Chen, Yao-Chang, Chung, Cheng-Chih, Tsai, Wen-Chin, Kao, Yu-Hsun, Lee, Ting-I, Chen, Yi-Jen

“…Peroxisome proliferator-activated receptors (PPARs) regulate cardiac glucose and lipid homeostasis. Histone deacetylase (HDAC) inhibitor has anti-inflammatory…”
Get full text