Search Results - "Chundi, Xu"

Neuronal polarization by Takano, Tetsuya, Xu, Chundi, Funahashi, Yasuhiro, Namba, Takashi, Kaibuchi, Kozo

“…Neurons are highly polarized cells with structurally and functionally distinct processes called axons and dendrites. This polarization underlies the…”
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Multi-omics reveals that Bifidobacterium breve M-16V may alleviate the immune dysregulation caused by nanopolystyrene by Li, Na, Wang, Jun, Liu, Ping, Li, Jinhua, Xu, Chundi

“…[Display omitted] •Immunoassay reveals Th2-driven immunotoxicity elicited by polystyrene (PS).•Intestinal differential genes relate to PS-induced immune…”
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Extracellular and Intracellular Signaling for Neuronal Polarity by Namba, Takashi, Funahashi, Yasuhiro, Nakamuta, Shinichi, Xu, Chundi, Takano, Tetsuya, Kaibuchi, Kozo

“…Neurons are one of the highly polarized cells in the body. One of the fundamental issues in neuroscience is how neurons establish their polarity; therefore,…”
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Runt-Related Transcription Factor 1 (RUNX1) Promotes TGF-β-Induced Renal Tubular Epithelial-to-Mesenchymal Transition (EMT) and Renal Fibrosis through the PI3K Subunit p110δ by Zhou, Tong, Luo, Maocai, Cai, Wei, Zhou, Siyuan, Feng, Danying, Xu, Chundi, Wang, Hongyan

“…Renal fibrosis is widely considered a common mechanism leading to end-stage renal failure. Epithelial-to-mesenchymal transition (EMT) plays important roles in…”
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Notch signaling and Bsh homeodomain activity are integrated to diversify Drosophila lamina neuron types by Xu, Chundi, Ramos, Tyler B, Marshall, Owen J, Doe, Chris Q

“…Notch signaling is an evolutionarily conserved pathway for specifying binary neuronal fates, yet how it specifies different fates in different contexts remains…”
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Radial Glial Cell-Neuron Interaction Directs Axon Formation at the Opposite Side of the Neuron from the Contact Site by Xu, Chundi, Funahashi, Yasuhiro, Watanabe, Takashi, Takano, Tetsuya, Nakamuta, Shinichi, Namba, Takashi, Kaibuchi, Kozo

“…How extracellular cues direct axon-dendrite polarization in mouse developing neurons is not fully understood. Here, we report that the radial glial cell…”
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Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity by Xu, Chundi, Ramos, Tyler B, Rogers, Edward M, Reiser, Michael B, Doe, Chris Q

“…How our brain generates diverse neuron types that assemble into precise neural circuits remains unclear. Using lamina neuron types (L1-L5), we show that the…”
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Multi-omics reveals the mechanisms of DEHP driven pulmonary toxicity in ovalbumin-sensitized mice by Liu, Ping, Quan, Xu, Zhang, Qingqing, Chen, Yanyan, Wang, Xinqiong, Xu, Chundi, Li, Na

“…The plasticizer di- (2-ethylhexyl) phthalate (DEHP) is considered a risk factor for allergic diseases and has attracted public attention for its adverse…”
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Discovery of long-range inhibitory signaling to ensure single axon formation by Takano, Tetsuya, Wu, Mengya, Nakamuta, Shinichi, Naoki, Honda, Ishizawa, Naruki, Namba, Takashi, Watanabe, Takashi, Xu, Chundi, Hamaguchi, Tomonari, Yura, Yoshimitsu, Amano, Mutsuki, Hahn, Klaus M., Kaibuchi, Kozo

“…A long-standing question in neurodevelopment is how neurons develop a single axon and multiple dendrites from common immature neurites. Long-range inhibitory…”
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ERp29 forms a feedback regulation loop with microRNA-135a-5p and promotes progression of colorectal cancer by Huang, Jiebin, Jing, Mengxia, Chen, Xixi, Gao, Yuanqi, Hua, Huiying, Pan, Chun, Wu, Jing, Wang, Xinqiong, Chen, Xuehua, Gao, Yujing, Xu, Chundi, Li, Pu

“…Expression of endoplasmic reticulum (ER) stress-associated genes is often dysregulated in cancer progression. ER protein 29 (ERp29) is abnormally expressed in…”
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miR-122 targets NOD2 to decrease intestinal epithelial cell injury in Crohn’s disease by Chen, Yu, Wang, Chengxiao, Liu, Ying, Tang, Liwei, Zheng, Mingxia, Xu, Chundi, Song, Jian, Meng, Xiaochun

“…•NOD2 is a target gene of miR-122.•miR-122 inhibits LPS-induced apoptosis by suppressing NOD2 in HT-29 cells.•miR-122 reduces the expression of…”
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Control of Synaptic Specificity by Establishing a Relative Preference for Synaptic Partners by Xu, Chundi, Theisen, Emma, Maloney, Ryan, Peng, Jing, Santiago, Ivan, Yapp, Clarence, Werkhoven, Zachary, Rumbaut, Elijah, Shum, Bryan, Tarnogorska, Dorota, Borycz, Jolanta, Tan, Liming, Courgeon, Maximilien, Griffin, Tessa, Levin, Raina, Meinertzhagen, Ian A., de Bivort, Benjamin, Drugowitsch, Jan, Pecot, Matthew Y.

“…The ability of neurons to identify correct synaptic partners is fundamental to the proper assembly and function of neural circuits. Relative to other steps in…”
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Identification of FCN1 as a novel macrophage infiltration-associated biomarker for diagnosis of pediatric inflammatory bowel diseases by Chen, Xixi, Gao, Yuanqi, Xie, Jinfang, Hua, Huiying, Pan, Chun, Huang, Jiebin, Jing, Mengxia, Chen, Xuehua, Xu, Chundi, Gao, Yujing, Li, Pu

“…The incidence of pediatric inflammatory bowel disease (PIBD) has been steadily increasing globally. Delayed diagnosis of PIBD increases the risk of…”
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Characteristics of Fecal Microbiota and Machine Learning Strategy for Fecal Invasive Biomarkers in Pediatric Inflammatory Bowel Disease by Wang, Xinqiong, Xiao, Yuan, Xu, Xu, Guo, Li, Yu, Yi, Li, Na, Xu, Chundi

“…Early diagnosis and treatment of pediatric Inflammatory bowel disease (PIBD) is challenging due to the complexity of the disease and lack of disease specific…”
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Drosophila Fezf coordinates laminar-specific connectivity through cell-intrinsic and cell-extrinsic mechanisms by Peng, Jing, Santiago, Ivan J, Ahn, Curie, Gur, Burak, Tsui, C Kimberly, Su, Zhixiao, Xu, Chundi, Karakhanyan, Aziz, Silies, Marion, Pecot, Matthew Y

“…Laminar arrangement of neural connections is a fundamental feature of neural circuit organization. Identifying mechanisms that coordinate neural connections…”
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Probiotic lactic acid bacteria alleviate pediatric IBD and remodel gut microbiota by modulating macrophage polarization and suppressing epithelial apoptosis by Hua, Huiying, Pan, Chun, Chen, Xixi, Jing, Mengxia, Xie, Jinfang, Gao, Yuanqi, Huang, Jiebin, Chen, Xuehua, Gao, Yujing, Xu, Chundi, Li, Pu

“…The incidence of pediatric inflammatory bowel disease (PIBD) continues to rise. It was reported that the probiotic lactic acid bacteria ( ) can interfere with…”
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A narrative review on the role of genetics in children with acute recurrent pancreatitis and chronic pancreatitis by Yu, Bo, Yu, Yi, Wang, Xinqiong, Xu, Chundi, Xiao, Yuan

“…ABSTRACT The incidence of pancreatitis in children has increased over the past two decades. With advances in molecular biological techniques and clinical…”
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DC-SIGN and Toll-like receptor 4 mediate oxidized low-density lipoprotein-induced inflammatory responses in macrophages by Yang, Ke, Liu, Xinhe, Liu, Yan, Wang, Xinqiong, Cao, Lijuan, Zhang, Xiaojie, Xu, Chundi, Shen, Weifeng, Zhou, Tong

“…The regulation of inflammatory responses by innate immune receptors is recognized as a crucial step in the development of atherosclerosis, although the precise…”
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Control of Synaptic Specificity by Establishing a Relative Preference for Synaptic Partners by Xu, Chundi, Theisen, Emma, Maloney, Ryan, Peng, Jing, Santiago, Ivan, Yapp, Clarence, Werkhoven, Zachary, Rumbaut, Elijah, Shum, Bryan, Tarnogorska, Dorota, Borycz, Jolanta, Tan, Liming, Courgeon, Maximilien, Griffin, Tessa, Levin, Raina, Meinertzhagen, Ian A., de Bivort, Benjamin, Drugowitsch, Jan, Pecot, Matthew Y.

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Association between Helicobacter pylori Infection and Pathological Changes in the Gastric Mucosa in Chinese Children by Yu, Yi, Su, Lin, Wang, Xinqiong, Wang, Xiaojin, Xu, Chundi

“…Objective H. pylori infection in children has a high prevalence worldwide. The disease can cause progressive gastric mucosal inflammation, as verified in…”
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