Search Results - "Chun-Wai Mai"

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma by Pua, Lesley Jia Wei, Mai, Chun-Wai, Chung, Felicia Fei-Lei, Khoo, Alan Soo-Beng, Leong, Chee-Onn, Lim, Wei-Meng, Hii, Ling-Wei

“…c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family members integrate signals that affect proliferation, differentiation,…”
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Therapeutic challenges and current immunomodulatory strategies in targeting the immunosuppressive pancreatic tumor microenvironment by Looi, Chin-King, Chung, Felicia Fei-Lei, Leong, Chee-Onn, Wong, Shew-Fung, Rosli, Rozita, Mai, Chun-Wai

“…Pancreatic cancer is one of the most lethal type of cancers, with an overall five-year survival rate of less than 5%. It is usually diagnosed at an advanced…”
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Potential of Superhydrophobic Surface for Blood-Contacting Medical Devices by Wu, Xun Hui, Liew, Yun Khoon, Mai, Chun-Wai, Then, Yoon Yee

“…Medical devices are indispensable in the healthcare setting, ranging from diagnostic tools to therapeutic instruments, and even supporting equipment. However,…”
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Blood compatible and noncytotoxic superhydrophobic graphene/titanium dioxide coating with antibacterial and antibiofilm properties by Wu, Xun Hui, Liew, Yun Khoon, Lim, Wei Meng, Mai, Chun‐Wai, Then, Yoon Yee

“…The potential of superhydrophobic surfaces has gained vast attention in medical settings due to their self‐cleaning effect (including bacterial colonization…”
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Recent Emergence of Rhenium(I) Tricarbonyl Complexes as Photosensitisers for Cancer Therapy by Liew, Hui Shan, Mai, Chun-Wai, Zulkefeli, Mohd, Madheswaran, Thiagarajan, Kiew, Lik Voon, Delsuc, Nicolas, Low, May Lee

“…Photodynamic therapy (PDT) is emerging as a significant complementary or alternative approach for cancer treatment. PDT drugs act as photosensitisers, which…”
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Molecular Mechanism of Tocotrienol-Mediated Anticancer Properties: A Systematic Review of the Involvement of Endoplasmic Reticulum Stress and Unfolded Protein Response by Pang, Kok-Lun, Mai, Chun-Wai, Chin, Kok-Yong

“…Tocotrienol, a type of vitamin E, is well known for its anti-cancer and other biological activities. This systematic review aims to summarize the involvement…”
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Cudraflavone C Induces Tumor-Specific Apoptosis in Colorectal Cancer Cells through Inhibition of the Phosphoinositide 3-Kinase (PI3K)-AKT Pathway by Soo, Hsien-Chuen, Chung, Felicia Fei-Lei, Lim, Kuan-Hon, Yap, Veronica Alicia, Bradshaw, Tracey D, Hii, Ling-Wei, Tan, Si-Hoey, See, Sze-Jia, Tan, Yuen-Fen, Leong, Chee-Onn, Mai, Chun-Wai

“…Cudraflavone C (Cud C) is a naturally-occurring flavonol with reported anti-proliferative activities. However, the mechanisms by which Cud C induced…”
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Drug‐like dietary vanilloids induce anticancer activity through proliferation inhibition and regulation of bcl‐related apoptotic proteins by Mai, Chun‐Wai, Kang, Yew‐Beng, Nadarajah, Vishna Devi, Hamzah, Ahmad Sazali, Pichika, Mallikarjuna Rao

“…In this study, a series of 20 structurally similar vanilloids (Vn) were tested for their antiproliferative effects against 12 human cancer cells: human breast…”
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TP53 loss‐of‐function causes vulnerability to autophagy inhibition in aggressive prostate cancer by Zhang, Yong, Song, Xian‐Li, Yu, Bin, Foong, Lian‐Chee, Shu, Yu, Mai, Chun‐Wai, Hu, Jing, Dong, Baijun, Xue, Wei, Chua, Chee Wai

“…Objectives TP53 loss‐of‐function is commonly found in aggressive prostate cancer. However, a highly‐efficient therapy for this tumor subtype is still lacking…”
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Modeling prostate cancer: What does it take to build an ideal tumor model? by Mai, Chun-Wai, Chin, Kok-Yong, Foong, Lian-Chee, Pang, Kok-Lun, Yu, Bin, Shu, Yu, Chen, Sisi, Cheong, Soon-Keng, Chua, Chee Wai

“…Prostate cancer is frequently characterized as a multifocal disease with great intratumoral heterogeneity as well as a high propensity to metastasize to bone…”
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Additivity vs Synergism: Investigation of the Additive Interaction of Cinnamon Bark Oil and Meropenem in Combinatory Therapy by Yang, Shun-Kai, Yusoff, Khatijah, Mai, Chun-Wai, Lim, Wei-Meng, Yap, Wai-Sum, Lim, Swee-Hua Erin, Lai, Kok-Song

“…Combinatory therapies have been commonly applied in the clinical setting to tackle multi-drug resistant bacterial infections and these have frequently proven…”
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Histone deacetylase (HDAC) inhibitors and doxorubicin combinations target both breast cancer stem cells and non-stem breast cancer cells simultaneously by Hii, Ling-Wei, Chung, Felicia Fei-Lei, Soo, Jaslyn Sian-Siu, Tan, Boon Shing, Mai, Chun-Wai, Leong, Chee-Onn

“…Purpose Breast cancer stem cells (CSCs) are a small subpopulation of cancer cells that have high capability for self-renewal, differentiation, and tumor…”
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The Role of Ras-Associated Protein 1 (Rap1) in Cancer: Bad Actor or Good Player? by Looi, Chin-King, Hii, Ling-Wei, Ngai, Siew Ching, Leong, Chee-Onn, Mai, Chun-Wai

“…Metastasis is known as the most life-threatening event in cancer patients. In principle, the immune system can prevent tumor development. However,…”
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Phosphoinositide‐dependent Kinase‐1 (PDPK1) regulates serum/glucocorticoid‐regulated Kinase 3 (SGK3) for prostate cancer cell survival by Nalairndran, Geetha, Hassan Abdul Razack, Azad, Mai, Chun‐Wai, Fei‐Lei Chung, Felicia, Chan, Kok‐Keong, Hii, Ling‐Wei, Lim, Wei‐Meng, Chung, Ivy, Leong, Chee‐Onn

“…Prostate cancer (PCa) is the most common malignancy and is the second leading cause of cancer among men globally. Using a kinome‐wide lentiviral small‐hairpin…”
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Tocotrienols Modulate a Life or Death Decision in Cancers by Tham, Shiau-Ying, Loh, Hwei-San, Mai, Chun-Wai, Fu, Ju-Yen

“…Malignancy often arises from sophisticated defects in the intricate molecular mechanisms of cells, rendering a complicated molecular ground to effectively…”
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Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells by Nalairndran, Geetha, Chung, Ivy, Abdul Razack, Azad Hassan, Chung, Felicia Fei‐Lei, Hii, Ling‐Wei, Lim, Wei‐Meng, Looi, Chin King, Mai, Chun‐Wai, Leong, Chee‐Onn

“…Prostate cancer (PCa) is the second most common malignancy and is the fifth leading cause of cancer mortality among men globally. Docetaxel‐based therapy…”
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Molecular Hybrids Integrated with Benzimidazole and Pyrazole Structural Motifs: Design, Synthesis, Biological Evaluation, and Molecular Docking Studies by Sivaramakarthikeyan, Ramar, Iniyaval, Shunmugam, Saravanan, Vadivel, Lim, Wei-Meng, Mai, Chun-Wai, Ramalingan, Chennan

“…Synthesis of a series of benzimidazole-ornamented pyrazoles, 6a–6j has been obtained from arylhydrazine and aralkyl ketones via a multistep synthetic strategy…”
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Global Antimicrobial Stewardship: A Closer Look at the Formidable Implementation Challenges by Tiong, John J L, Loo, Jason S E, Mai, Chun-Wai

“…Antimicrobial stewardship (AMS) has been touted as one of the key strategies required in tackling worldwide escalation of antibiotic resistance. Although AMS…”
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Academic dishonesty among academics in Malaysia: a comparison between healthcare and non-healthcare academics by Tiong, John Jeh Lung, Kho, Hui Ling, Mai, Chun-Wai, Lau, Hui Ling, Hasan, Syed Shahzad

“…This study was carried out to gauge the prevalence of academic dishonesty among academics in Malaysian universities. A direct comparison was made between…”
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Molecular Mechanisms and Potential Therapeutic Reversal of Pancreatic Cancer-Induced Immune Evasion by Gan, Li-Lian, Hii, Ling-Wei, Wong, Shew-Fung, Leong, Chee-Onn, Mai, Chun-Wai

“…Pancreatic cancer ranks high among the causes of cancer-related mortality. The prognosis of this grim condition has not improved significantly over the past 50…”
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