Search Results - "Chun, Donald"

The pharmacokinetic profile of brensocatib and its effect on pharmacodynamic biomarkers including NE, PR3, and CatG in various rodent species by Basso, Jessica, Chen, Kuan-Ju, Zhou, Yuchen, Mark, Lilly, LaSala, Daniel, Dorfman, Arielle, Atalla, Mary, Chun, Donald, Viramontes, Veronica, Chang, Christina, Leifer, Franziska, McDonald, Patrick P, Cipolla, David C

“…Brensocatib is a novel, oral, selective, reversible inhibitor of dipeptidyl peptidase 1 (DPP1), which activates several neutrophil serine proteases (NSPs),…”
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Brensocatib, an oral, reversible inhibitor of dipeptidyl peptidase 1, mitigates interferon-α-accelerated lupus nephritis in mice by Chen, Kuan-Ju, Zhang, Jimin, LaSala, Daniel, Basso, Jessica, Chun, Donald, Zhou, Yuchen, McDonald, Patrick P, Perkins, Walter R, Cipolla, David C

“…Neutrophils have been implicated in initiating and perpetuating systemic lupus erythematosus and the resultant kidney damage in lupus nephritis (LN) patients,…”
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Development and Characterization of Treprostinil Palmitil Inhalation Aerosol for the Investigational Treatment of Pulmonary Arterial Hypertension by Plaunt, Adam J, Islam, Sadikul, Macaluso, Tony, Gauani, Helena, Baker, Thomas, Chun, Donald, Viramontes, Veronica, Chang, Christina, Corboz, Michel R, Chapman, Richard W, Li, Zhili, Cipolla, David C, Perkins, Walter R, Malinin, Vladimir S

“…Treprostinil palmitil (TP) is a prodrug of treprostinil (TRE), a pulmonary vasodilator that has been previously formulated for inhaled administration via a…”
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Preclinical Investigation of a Lipoglycopeptide Dry Powder Inhalation Therapy for the Treatment of Pulmonary MRSA Infection by Konicek, Donna M, Plaunt, Adam J, Gharse, Sachin, Rose, Sasha J, Dorfman, Arielle, Sabnis, Amruta, Baker, Thomas, Gauani, Helena, Chun, Donald, Li, Zhili, Perkins, Walter R, Cipolla, David, Malinin, Vladimir S

“…The increased prevalence of pulmonary methicillin-resistant Staphylococcus aureus (MRSA) infection in patients living with cystic fibrosis (CF) is concerning…”
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Assessment of Inhaled Treprostinil Palmitil, Inhaled and Intravenous Treprostinil, and Oral Selexipag in a Sugen/Hypoxia Rat Model of Pulmonary Arterial Hypertension by Corboz, Michel R, Plaunt, Adam J, Malinin, Vladimir S, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R, Chapman, Richard W

“…Treprostinil palmitil (TP), a long-acting inhaled pulmonary vasodilator prodrug of treprostinil (TRE), has beneficial effects in a Sugen5416/hypoxia (Su/Hx)…”
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Treprostinil palmitil inhibits the hemodynamic and histopathological changes in the pulmonary vasculature and heart in an animal model of pulmonary arterial hypertension by Corboz, Michel R., Plaunt, Adam J., Malinin, Vladimir, Li, Zhili, Gauani, Helena, Chun, Donald, Cipolla, David, Perkins, Walter R., Chapman, Richard W.

“…Treprostinil palmitil (TP) is a long-acting inhaled pulmonary vasodilator prodrug of treprostinil (TRE). In this study, TP was delivered by inhalation…”
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Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections by Plaunt, Adam J, Rose, Sasha J, Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P, Dorfman, Arielle, Smith, Barrett T, Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G, Corboz, Michel R, Chapman, Richard W, Cipolla, David, Perkins, Walter R, Malinin, Vladimir S, Konicek, Donna M

“…Chronic pulmonary methicillin-resistant Staphylococcus aureus (MRSA) disease in cystic fibrosis (CF) has a high probability of recurrence following treatment…”
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Correction for Plaunt et al., “Development and Preclinical Evaluation of New Inhaled Lipoglycopeptides for the Treatment of Persistent Pulmonary Methicillin-Resistant Staphylococcus aureus Infections” by Plaunt, Adam J., Rose, Sasha J., Kang, Jeong Yeon, Chen, Kuan-Ju, LaSala, Daniel, Heckler, Ryan P., Dorfman, Arielle, Smith, Barrett T., Chun, Donald, Viramontes, Veronica, Macaluso, Antonio, Li, Zhili, Zhou, Yuchen, Mark, Lilly, Basso, Jessica, Leifer, Franziska G., Corboz, Michel R., Chapman, Richard W., Cipolla, David, Perkins, Walter R., Malinin, Vladimir S., Konicek, Donna M.

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Treprostinil palmitil, an inhaled long-acting pulmonary vasodilator, does not show tachyphylaxis with daily dosing in rats by Chapman, Richard W., Li, Zhili, Chun, Donald, Gauani, Helena, Malinin, Vladimir, Plaunt, Adam J., Cipolla, David, Perkins, Walter R., Corboz, Michel R.

“…Treprostinil palmitil (TP) is an inhaled long-acting pulmonary vasodilator prodrug of treprostinil (TRE) that has been formulated for delivery as a suspension…”
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A New Approach to Automated Epileptic Diagnosis Using EEG and Probabilistic Neural Network by Bao, F.S., Lie, D.Y.-C., Yuanlin Zhang

“…Epilepsy is one of the most common neurological disorders that greatly impair patients' daily lives. Traditional epileptic diagnosis relies on tedious visual…”
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A cell-based assay for screening the uridine 5 ′-diphosphate–glucuronosyltransferase 1A inhibitory potential of new chemical entities by Padrós, Jaime, Chun, Donald, Chen, Liangfu, Rigolli, Pierre, Flarakos, Themis, Jurima-Romet, Mallé

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A New Approach to Automated Epileptic Diagnosis Using EEG and Probabilistic Neural Network by Bao, Forrest Sheng, Lie, Donald Yu-Chun, Zhang, Yuanlin

“…Epilepsy is one of the most common neurological disorders that greatly impair patient' daily lives. Traditional epileptic diagnosis relies on tedious visual…”
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Ion implantation in epitaxial germanium(x) silicon(1-x) on silicon(100) by Lie, Yu-Chun Donald

“…The question of whether one can effectively dope or process epitaxial Si(100)/GeSi heterostructures by ion implantation is experimentally investigated. Results…”
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Acute interstitial edematous pancreatitis： Findings on non-enhanced MR imaging by Zhang, Xiao-Ming, Feng, Zhi-Song, Zhao, Qiong-Hui, Xiao, Chun-Ming, Mitchell, Donald-G, Shu, Jian, Zeng, Nan-Lin, Xu, Xiao-Xue, Lei, Jun-Yang, Tian, Xiao-Bing

“…AIM： To study the appearances of acute interstitial edematous pancreatitis （IEP） on non-enhanced MR imaging. METHODS： A total of 53 patients with IEP diagnosed…”
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