Search Results - "Chulanov, V"
-
1
Bulevirtide improves health-related quality of life measured by EQ-5D VAS in patients with chronic hepatitis delta: An exploratory analysis of a Phase 3 trial at 48 weeks
Published in DIGESTIVE AND LIVER DISEASE (01-03-2023)“…Chronic hepatitis delta (CHD) is the most severe form of viral hepatitis and is associated with rapid progression to cirrhosis, decompensation, hepatocellular…”
Get full text
Journal Article Conference Proceeding -
2
Efficacy of bulevirtide as monotherapy for chronic hepatitis D (CHD): Week 48 results from an integrated analysis
Published in DIGESTIVE AND LIVER DISEASE (01-03-2023)“…Bulevirtide (BLV) is a novel first-in-class entry inhibitor for the treatment of chronic hepatitis delta virus (HDV) infection (CHD) that was conditionally…”
Get full text
Journal Article Conference Proceeding -
3
Serological diagnosis and prevalence of HIV-1 infection in Russian metropolitan areas
Published in BMC infectious diseases (07-01-2021)“…HIV infection is a major health problem in Russia. We aimed to assess HIV prevalence in different population groups and to compare the characteristics of 4th…”
Get full text
Journal Article -
4
Antiviral Activity of CRISPR/Cas9 Ribonucleoprotein Complexes on a Hepatitis B Virus Model In Vivo
Published in Molecular biology (New York) (01-12-2022)“…Chronic hepatitis B (CHB) is caused by hepatitis B virus (HBV) infection. This disease is a key issue for global health. Modern methods of therapy do not…”
Get full text
Journal Article -
5
Stochastic Packaging of Cas Proteins into Exosomes
Published in Molekuliarnaia biologiia (15-02-2024)“…CRISPR/Cas systems are perspective molecular tools for targeted manipulation with genetic materials, such as gene editing, regulation of gene transcription,…”
Get more information
Journal Article -
6
Stochastic Packaging of Cas Proteins into Exosomes
Published in Molecular biology (New York) (01-02-2024)“…—CRISPR/Cas systems are perspective molecular tools for targeted manipulation with genetic materials, such as gene editing, regulation of gene transcription,…”
Get full text
Journal Article -
7
HBx Protein Potentiates Hepatitis B Virus Reactivation
Published in Molecular biology (New York) (01-10-2022)“…Hepatitis B virus (HBV) can cause chronic hepatitis B, one of the most prevalent infectious diseases in the world. Global estimates suggest that over 2 billion…”
Get full text
Journal Article -
8
Small Molecular Inhibitors of DNA Double Strand Break Repair Pathways Increase the ANTI-HBV Activity of CRISPR/Cas9
Published in Molecular biology (New York) (01-03-2019)“…The CRISPR/Cas9 nuclease system can effectively suppress the replication of the hepatitis B virus (HBV), while covalently closed circular DNA (cccDNA), a…”
Get full text
Journal Article -
9
Sofosbuvir/velpatasvir for the treatment of HCV: excellent results from a phase-3, open-label study in Russia and Sweden
Published in Infectious diseases (London, England) (01-02-2019)“…Background: In both Russia and Sweden, the dominant hepatitis C virus (HCV) is genotype 1, but around one-third of patients have genotype 3 infection. For such…”
Get full text
Journal Article -
10
P1285 : Forecasting the disease burden of chronic hepatitis C in Russia
Published in Journal of hepatology (01-04-2015)Get full text
Journal Article -
11
Efficacy and safety of narlaprevir/ritonavir and daclatasvir non interferon combination in population of Russian patients with chronic hepatitis C
Published in Terapevtic̆eskii arhiv (15-08-2019)“…Aim. Evaluate efficacy and safety of a combination of direct - acting antivirals narlaprevir/ritonavir with daclatasvir in patients with viral hepatitis C…”
Get full text
Journal Article -
12
Hepatitis C can be cured: will hepatitis B become next?
Published in Terapevtic̆eskii arhiv (01-01-2017)“…Chronic hepatitis B (CHB) and C (CHC) are one of the leading causes of cirrhosis and liver cancer with over a million of people dying annually from their…”
Get full text
Journal Article -
13
INCREASED FORMATION OF PHOSPHORYLATED H2AX FOCI IN NUCLEI OF CELLS INFECTED BY HEPATITIS B AND B+D VIRUSES
Published in Voprosy virusologiĭ (20-08-2018)“…Liver cirrhosis and hepatocellular carcinoma are the most common outcomes of chronic hepatitis B. Hepatitis B virus (HBV) induces transformation and cell death…”
Get full text
Journal Article -
14
Pharmacoeconomic analysis of tixagevimab and cilgavimab combination for COVID-19 therapy
Published in Farmakoèkonomika (Moskva. Online) (20-07-2023)“…Objective : to evaluate the pharmacoeconomic feasibility of using monoclonal antibodies or their combinations vs standard therapy in patients with mild and…”
Get full text
Journal Article -
15
Overexpression of DNA-methyltransferases in persistency of cccDNA pool in chronic hepatitis B
Published in Terapevtic̆eskii arhiv (01-01-2017)“…Aim. To define the role of DNA-methyltransferases of type 1 and type 3A in hepatitis B viral cycle. Materials and methods. Human hepatoma cells HepG2 with…”
Get full text
Journal Article -
16
-
17
Resistance to protease inhibitors and efficiency of antiviral therapy in patients with chronic hepatitis C
Published in Terapevtic̆eskii arhiv (01-01-2016)“…To clarify the role of virus resistance in the efficiency of antiviral therapy with protease inhibitors (PIs) chronic hepatitis C (CHC) patients, with moderate…”
Get full text
Journal Article -
18
Epidemiological Features of the COVID-19 and Characteristics of Patients during the Spread of the Omicron SARS-COV-2 in Russia
Published in Èpidemiologiâ i vakcinoprofilaktika (Online) (09-09-2024)“…Aim. To analyze dynamic of incidence and mortality of COVID-19 and clinical and epidemiological characteristics of adult patients with a new coronavirus…”
Get full text
Journal Article -
19
Features of the covid-19 epidemic and characteristics of patients during the spread of the delta SARS-COV-2 in Russia
Published in Zhurnal infektologii (22-09-2024)“…Aim: To study the manifestations of the COVID-19 epidemic and the clinical and epidemiological characteristics of adult patients with a new coronavirus…”
Get full text
Journal Article -
20
Chronic hepatitis C in Russia: current challenges and prospects
Published in Terapevtic̆eskii arhiv (01-01-2015)“…This paper evaluates the impact of different medical care strategies for chronic hepatitis C patients in relation to its prevalence, frequency of adverse…”
Get full text
Journal Article