Search Results - "Chul Kang"

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    The use of technical replication for detection of low-level somatic mutations in next-generation sequencing by Kim, Junho, Kim, Dachan, Lim, Jae Seok, Maeng, Ju Heon, Son, Hyeonju, Kang, Hoon-Chul, Nam, Hojung, Lee, Jeong Ho, Kim, Sangwoo

    Published in Nature communications (05-03-2019)
    “…Accurate genome-wide detection of somatic mutations with low variant allele frequency (VAF, <1%) has proven difficult, for which generalized, scalable methods…”
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    Brain somatic mutations in MTOR cause focal cortical dysplasia type II leading to intractable epilepsy by Lim, Jae Seok, Kim, Woo-il, Kang, Hoon-Chul, Kim, Se Hoon, Park, Ah Hyung, Park, Eun Kyung, Cho, Young-Wook, Kim, Sangwoo, Kim, Ho Min, Kim, Jeong A, Kim, Junho, Rhee, Hwanseok, Kang, Seok-Gu, Kim, Heung Dong, Kim, Daesoo, Kim, Dong-Seok, Lee, Jeong Ho

    Published in Nature medicine (01-04-2015)
    “…Deep sequencing identifies somatic activating mutations of MTOR in affected brain regions of FCDII patients that are sufficient to cause neuronal migration…”
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    Tumor Regression In Vivo by Photothermal Therapy Based on Gold-Nanorod-Loaded, Functional Nanocarriers by Choi, Won Il, Kim, Ja-Young, Kang, Chul, Byeon, Clare C, Kim, Young Ha, Tae, Giyoong

    Published in ACS nano (22-03-2011)
    “…We developed a very effective hyperthermia system for successful photothermal cancer therapy. Instead of applying individual gold nanorods (GNRs) that can…”
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    Common genes and recurrent causative variants in 957 Asian patients with pediatric epilepsy by Kim, Se Hee, Seo, Jieun, Kwon, Soon Sung, Teng, Lip‐Yuen, Won, DongJu, Shin, Saeam, Lee, Joon Soo, Lee, Seung‐Tae, Choi, Jong Rak, Kang, Hoon‐Chul

    Published in Epilepsia (Copenhagen) (01-03-2024)
    “…Objective We aimed to identify common genes and recurrent causative variants in a large group of Asian patients with different epilepsy syndromes and…”
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    Estimating Cloth Simulation Parameters From Tag Information and Cusick Drape Test by Ju, Eunjung, Kim, Kwang‐yun, Yoon, Sungjin, Shim, Eungjune, Kang, Gyoo‐Chul, Chang, Phil Sik, Choi, Myung Geol

    Published in Computer graphics forum (01-05-2024)
    “…In recent years, the fashion apparel industry has been increasingly employing virtual simulations for the development of new products. The first step in…”
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    Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy by Kim, Jeong A, Yoon, Jung‐Rim, Lee, Eun Joo, Lee, Joon Soo, Kim, Jeong Tae, Kim, Heung Dong, Kang, Hoon‐Chul

    Published in Epilepsia (Copenhagen) (01-01-2016)
    “…Summary Objective We aimed to compare the efficacy, safety, and tolerability of a modified Atkins diet (MAD) with the classic ketogenic diet (KD) for the…”
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    Precise detection of low-level somatic mutation in resected epilepsy brain tissue by Sim, Nam Suk, Ko, Ara, Kim, Woo Kyeong, Kim, Se Hoon, Kim, Ju Seong, Shim, Kyu-Won, Aronica, Eleonora, Mijnsbergen, Caroline, Spliet, Wim G. M., Koh, Hyun Yong, Kim, Heung Dong, Lee, Joon Soo, Kim, Dong Seok, Kang, Hoon-Chul, Lee, Jeong Ho

    Published in Acta neuropathologica (01-12-2019)
    “…Low-level somatic mutations have been shown to be the major genetic etiology of intractable epilepsy. The extents thereof, however, have yet to be…”
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    Brain Somatic Mutations in MTOR Disrupt Neuronal Ciliogenesis, Leading to Focal Cortical Dyslamination by Park, Sang Min, Lim, Jae Seok, Ramakrishina, Suresh, Kim, Se Hoon, Kim, Woo Kyeong, Lee, Junehawk, Kang, Hoon-Chul, Reiter, Jeremy F., Kim, Dong Seok, Kim, Hyongbum (Henry), Lee, Jeong Ho

    Published in Neuron (Cambridge, Mass.) (11-07-2018)
    “…Focal malformations of cortical development (FMCDs), including focal cortical dysplasia (FCD) and hemimegalencephaly (HME), are major etiologies of pediatric…”
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    BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors by Koh, Hyun Yong, Kim, Se Hoon, Jang, Jaeson, Kim, Hyungguk, Han, Sungwook, Lim, Jae Seok, Son, Geurim, Choi, Junjeong, Park, Byung Ouk, Heo, Won Do, Han, Jinju, Lee, Hyunjoo Jenny, Lee, Daeyoup, Kang, Hoon-Chul, Shong, Minho, Paik, Se-Bum, Kim, Dong Seok, Lee, Jeong Ho

    Published in Nature medicine (01-11-2018)
    “…Pediatric brain tumors are highly associated with epileptic seizures 1 . However, their epileptogenic mechanisms remain unclear. Here, we show that the…”
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    Characterization of Weissella confusa DD_A7 isolated from kimchi by Dey, Debasish Kumar, Koo, Bon Gyo, Sharma, Chanchal, Kang, Sun Chul

    Published in Food science & technology (01-08-2019)
    “…Foodborne pathogenic bacteria like, Escherichia coli 0157:H7, Bacillus cereus and Salmonella typhimurium are the biggest threat to food industries. Their…”
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    Determination of Dy substitution site in Nd2−xDyxFe14B by HAADF-STEM and illustration of magnetic anisotropy of “g” and “f” sites, before and after substitution by Haider, Syed Kamran, Kang, Min-Chul, Hong, Jisang, Kang, Young Soo, Yang, Cheol-Woong, Kim, Dongsoo

    Published in Scientific reports (18-03-2021)
    “…Nd 2 Fe 14 B and Nd 2−x Dy x Fe 14 B (x = 0.25, 0.50) particles were prepared by the modified co-precipitation followed by reduction–diffusion process. Bright…”
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    Effect of Different Grain Boundary Diffusion Alloys on Magnetic Properties of Dy-Free Sintered NdFeB Magnet by Tang, Wei, Wang, Jing, Pan, Chaochao, Kang, Min-Chul, Zhou, Lin, Kramer, Matthew J, Cui, Jun, Anderson, Iver E

    Published in IEEE transactions on magnetics (01-09-2024)
    “…Dy-free sintered magnets were fabricated by blending Neo powder with different grain boundary diffusion (GBD) alloy powders. Cu, CeAl, and CeAlCu have a…”
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    Mathematical Modeling and Analysis of a Piston Air Compressor of a Railway Vehicle for Abnormal Data Generation by Kim, Myeong-Joon, Cho, Hyun-Jik, Kang, Chul-Goo

    “…To effectively implement condition-based maintenance for the air compressor in a railway vehicle, a thorough understanding of its fault characteristics and the…”
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    Brain somatic mutations in MTOR reveal translational dysregulations underlying intractable focal epilepsy by Kim, Jang Keun, Cho, Jun, Kim, Se Hoon, Kang, Hoon-Chul, Kim, Dong-Seok, Kim, V Narry, Lee, Jeong Ho

    Published in The Journal of clinical investigation (01-10-2019)
    “…Brain somatic mutations confer genomic diversity in the human brain and cause neurodevelopmental disorders. Recently, brain somatic activating mutations in…”
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    Analysis of low-level somatic mosaicism reveals stage and tissue-specific mutational features in human development by Kim, Ja Hye, Hwang, Shinwon, Son, Hyeonju, Kim, Dongsun, Kim, Il Bin, Kim, Myeong-Heui, Sim, Nam Suk, Kim, Dong-Seok, Ha, Yoo-Jin, Lee, Junehawk, Kang, Hoon-Chul, Lee, Jeong Ho, Kim, Sangwoo

    Published in PLoS genetics (19-09-2022)
    “…Most somatic mutations that arise during normal development are present at low levels in single or multiple tissues depending on the developmental stage and…”
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    25-hydroxycholesterol contributes to cerebral inflammation of X-linked adrenoleukodystrophy through activation of the NLRP3 inflammasome by Jang, Jiho, Park, Sangjun, Jin Hur, Hye, Cho, Hyun-Ju, Hwang, Inhwa, Pyo Kang, Yun, Im, Isak, Lee, Hyunji, Lee, Eunju, Yang, Wonsuk, Kang, Hoon-Chul, Won Kwon, Sung, Yu, Je-Wook, Kim, Dong-Wook

    Published in Nature communications (25-10-2016)
    “…X-linked adrenoleukodystrophy (X-ALD), caused by an ABCD1 mutation, is a progressive neurodegenerative disorder associated with the accumulation of very…”
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    Ribosomal protein s15 phosphorylation mediates LRRK2 neurodegeneration in Parkinson's disease by Martin, Ian, Kim, Jungwoo Wren, Lee, Byoung Dae, Kang, Ho Chul, Xu, Jin-Chong, Jia, Hao, Stankowski, Jeannette, Kim, Min-Sik, Zhong, Jun, Kumar, Manoj, Andrabi, Shaida A, Xiong, Yulan, Dickson, Dennis W, Wszolek, Zbigniew K, Pandey, Akhilesh, Dawson, Ted M, Dawson, Valina L

    Published in Cell (10-04-2014)
    “…Mutations in leucine-rich repeat kinase 2 (LRRK2) are a common cause of familial and sporadic Parkinson's disease (PD). Elevated LRRK2 kinase activity and…”
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    Spatiotemporal coordination of the RSF1-PLK1-Aurora B cascade establishes mitotic signaling platforms by Lee, Ho-Soo, Min, Sunwoo, Jung, Ye-Eun, Chae, Sunyoung, Heo, June, Lee, Jae-Ho, Kim, TaeSoo, Kang, Ho-Chul, Nakanish, Makoto, Cha, Sun-Shin, Cho, Hyeseong

    Published in Nature communications (11-10-2021)
    “…The chromatin remodeler RSF1 enriched at mitotic centromeres is essential for proper chromosome alignment and segregation and underlying mechanisms remain to…”
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