Search Results - "Chul Choi, Hyoung"

Telomere stabilization by metformin mitigates the progression of atherosclerosis via the AMPK-dependent p-PGC-1α pathway by Sung, Jin Young, Kim, Seul Gi, Park, So-Young, Kim, Jae-Ryong, Choi, Hyoung Chul

“…Telomere dysfunction is a well-known molecular trigger of senescence and has been associated with various age-related diseases, including atherosclerosis…”
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Acute Inhibition of Guanosine Triphosphate Cyclohydrolase 1 Uncouples Endothelial Nitric Oxide Synthase and Elevates Blood Pressure by SHUANGXI WANG, JIAN XU, PING SONG, YONG WU, JUNHUA ZHANG, HYOUNG CHUL CHOI, ZOU, Ming-Hui

“…GTP cyclohydrolase 1 (GTPCH1) is the rate-limiting enzyme in de novo synthesis of tetrahydrobiopterin (BH4), an essential cofactor for endothelial NO synthase…”
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Enhanced Tyrosine Nitration of Prostacyclin Synthase Is Associated with Increased Inflammation in Atherosclerotic Carotid Arteries from Type 2 Diabetic Patients by He, Chaoyong, Chul Choi, Hyoung, Xie, Zhonglin

“…Prostacyclin synthase (PGIS) is tyrosine nitrated in diseased animals. Whether PGIS nitration occurs in human diabetic atherosclerotic arteries has not been…”
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Estrogenic compound attenuates angiotensin II-induced vascular smooth muscle cell proliferation through interaction between LKB1 and estrogen receptor α by Kim, Sun Ae, Lee, Kyung Young, Kim, Jae-Ryong, Choi, Hyoung Chul

“…The prevalence rate of cardiovascular disease is higher for males than females, and estradiol (E2) induces AMP-activated protein kinase (AMPK) activation,…”
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Reactive Nitrogen Species Is Required for the Activation of the AMP-activated Protein Kinase by Statin in Vivo by Choi, Hyoung Chul, Song, Ping, Xie, Zhonglin, Wu, Yong, Xu, Jian, Zhang, Miao, Dong, Yunzhou, Wang, Shuangxi, Lau, Kai, Zou, Ming-Hui

“…The AMP-activated protein kinase (AMPK) is reported to mediate the beneficial effects of statin on the vascular functions, but the biochemical mechanisms are…”
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Preparation and in vivo evaluation of lecithin-based microparticles for topical delivery of minoxidil by Lee, Hyo-Jung, Oh, Dong-Won, Na, Min-Ju, Kim, Dong-Wook, Yuk, Dong-Yeon, Choi, Hyoung-Chul, Lee, Yong-Beom, Han, Kun, Park, Chun-Woong

“…Minoxidil is widely used for treatment of androgenic alopecia. Commercial products containing minoxidil are usually in solution form. Repeated applications of…”
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Reparixin, an Inhibitor of CXCR1 and CXCR2 Receptor Activation, Attenuates Blood Pressure and Hypertension-Related Mediators Expression in Spontaneously Hypertensive Rats by Kim, Hye Young, Choi, Jin Hee, Kang, Young Jin, Park, So Young, Choi, Hyoung Chul, Kim, Hee Sun

“…Reparixin, an inhibitor of CXCL8 receptor CXCR1 and CXCR2 activation, has been shown to attenuate inflammatory responses in various injury models. In the…”
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Isoproterenol Inhibits Angiotensin II-Stimulated Proliferation and Reactive Oxygen Species Production in Vascular Smooth Muscle Cells through Heme Oxygenase-1 by Kim, Jung Eun, Kang, Young Jin, Lee, Kwang Youn, Choi, Hyoung Chul

“…Heme oxygenase (HO)-1 is a well-known cytoprotectant against oxidative stress and exhibits an antiproliferative effect in vascular smooth muscle cells (VSMCs)…”
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Reduction of AMP-Activated Protein Kinase α2 Increases Endoplasmic Reticulum Stress and Atherosclerosis In Vivo by YUNZHOU DONG, MIAO ZHANG, BIN LIANG, ZHONGLIN XIE, ZHENGXING ZHAO, ASFA, Sima, HYOUNG CHUL CHOI, ZOU, Ming-Hui

“…Background— Aberrant endoplasmic reticulum (ER) stress is associated with several cardiovascular diseases, including atherosclerosis. The mechanism by which…”
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Prednisolone suppresses adriamycin-induced vascular smooth muscle cell senescence and inflammatory response via the SIRT1-AMPK signaling pathway by Sung, Jin Young, Kim, Seul Gi, Kim, Jae-Ryong, Choi, Hyoung Chul

“…Cellular senescence is associated with inflammation and the senescence-associated secretory phenotype (SASP) of secreted proteins. Vascular smooth muscle cell…”
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Genistein-induced LKB1-AMPK activation inhibits senescence of VSMC through autophagy induction by Lee, Kyung Young, Kim, Jae-Ryong, Choi, Hyoung Chul

“…Abstract Genistein, the primary isoflavone from soy products, enhances antioxidant enzyme activities and inhibits tyrosine kinase. However, the mechanisms…”
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Apelin-13 Inhibits Methylglyoxal-Induced Unfolded Protein Responses and Endothelial Dysfunction via Regulating AMPK Pathway by Kim, Sujin, Kim, Suji, Hwang, Ae-Rang, Choi, Hyoung Chul, Lee, Ji-Yun, Woo, Chang-Hoon

“…It has been suggested that methylglyoxal (MGO), a glycolytic metabolite, has more detrimental effects on endothelial dysfunction than glucose itself. Recent…”
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Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo by YUNZHOU DONG, MIAO ZHANG, SHUANGXI WANG, BIN LIANG, ZHENGXING ZHAO, CHAO LIU, MINGYUAN WU, HYOUNG CHUL CHOI, LYONS, Timothy J, ZOU, Ming-Hui

“…The oxidation of LDLs is considered a key step in the development of atherosclerosis. How LDL oxidation contributes to atherosclerosis remains poorly defined…”
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Laminar Flow Activation of ERK5 Protein in Vascular Endothelium Leads to Atheroprotective Effect via NF-E2-related Factor 2 (Nrf2) Activation by Kim, Miso, Kim, Suji, Lim, Jae Hyang, Lee, ChuHee, Choi, Hyoung Chul, Woo, Chang-Hoon

“…Atherosclerosis is often observed in areas where disturbed flow is formed, whereas atheroprotective region is found in areas where steady laminar flow is…”
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A low-phase noise LC-QVCO in CMOS technology by HYOUNG CHUL CHOI, SO BONG SHIN, LEE, Sang-Gug

“…This letter presents a source-injection parallel coupled (SIPC) quadrature voltage-controlled oscillator (QVCO) topology. In the proposed SIPC-QVCO, compared…”
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SRT1720‐induced activation of SIRT1 alleviates vascular smooth muscle cell senescence through PKA‐dependent phosphorylation of AMPKα at Ser485 by Sung, Jin Young, Kim, Seul Gi, Cho, Du Hyong, Kim, Jae‐Ryong, Choi, Hyoung Chul

“…Aging is a major risk factor for hypertension and atherosclerosis, and vascular smooth muscle cell (VSMC) senescence can promote aging‐related vascular…”
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Nifedipine inhibits vascular smooth muscle cell proliferation and reactive oxygen species production through AMP-activated protein kinase signaling pathway by Sung, Jin Young, Choi, Hyoung Chul

“…Abstract The dihydropyridine calcium channel blocker nifedipine induces specific pharmacological effects by binding to L-type calcium channels, which results…”
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CD14 Glycoprotein Expressed in Vascular Smooth Muscle Cells by Choi, Hyoung Chul, Lee, Kwang Youn

“…The inducible nitric oxide synthase (iNOS) expression in vascular smooth muscle cells is an important factor for pathogenesis of septic shock or multiple organ…”
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Thromboxane A2 Receptor Activates a Rho-associated Kinase/LKB1/PTEN Pathway to Attenuate Endothelium Insulin Signaling by Song, Ping, Zhang, Miao, Wang, Shuangxi, Xu, Jian, Choi, Hyoung Chul, Zou, Ming-Hui

“…This study was conducted to elucidate the molecular mechanisms of thromboxane A2 receptor (TP)-induced insulin resistance in endothelial cells. Exposure of…”
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Diabetic Endothelium Dysfunction, Cardiovascular Complications, and Therapeutics by Dong, Yunzhou, Wu, Yong, Choi, Hyoung Chul, Wang, Shuangxi

“…W. Yu et al. suggested that Curcumin can improve cardiomyocyte function by inhibiting oxidative stress and apoptosis via the activation of Akt pathway; Z. Liu…”
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