Search Results - "Chul, Oh Byung"

Phosphoinositides and intracellular calcium signaling: novel insights into phosphoinositides and calcium coupling as negative regulators of cellular signaling by Oh, Byung-Chul

“…Intracellular calcium (Ca 2+ ) and phosphoinositides (PIPs) are crucial for regulating cellular activities such as metabolism and cell survival. Cells maintain…”
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Association between perfluoroalkyl substances exposure and thyroid function in adults: A meta-analysis by Kim, Min Joo, Moon, Shinje, Oh, Byung-Chul, Jung, Dawoon, Ji, Kyunghee, Choi, Kyungho, Park, Young Joo

“…Many people are exposed to perfluoroalkyl substances (PFASs) because these substances are widely used as industrial products. Although epidemiological studies…”
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Association Between Diethylhexyl Phthalate Exposure and Thyroid Function: A Meta-Analysis by Kim, Min Joo, Moon, Shinje, Oh, Byung-Chul, Jung, Dawoon, Choi, Kyungho, Park, Young Joo

“…Diethylhexyl phthalate (DEHP) is widely used in industrial products, particularly as plasticizers and softeners. Because it is used extensively, DEHP has been…”
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SREBP-1a–stimulated lipid synthesis is required for macrophage phagocytosis downstream of TLR4-directed mTORC1 by Lee, Jae-Ho, Phelan, Peter, Shin, Minsang, Oh, Byung-Chul, Han, Xianlin, Im, Seung-Soon, Osborne, Timothy F.

“…There is a growing appreciation for a fundamental connection between lipid metabolism and the immune response. Macrophage phagocytosis is a signature innate…”
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Deacetylation of XBP1s by sirtuin 6 confers resistance to ER stress-induced hepatic steatosis by Bang, In Hyuk, Kwon, Oh Kwang, Hao, Lihua, Park, Dami, Chung, Myung-Ja, Oh, Byung-Chul, Lee, Sangkyu, Bae, Eun Ju, Park, Byung-Hyun

“…The active spliced form of X-box-binding protein 1 (XBP1s) is a key modulator of ER stress, but the functional role of its post-translational modification…”
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Lomitapide, a cholesterol-lowering drug, is an anticancer agent that induces autophagic cell death via inhibiting mTOR by Lee, Boah, Park, Seung Ju, Lee, Seulgi, Lee, Jinwook, Lee, Eunbeol, Yoo, Eun-Seon, Chung, Won-Suk, Sohn, Jong-Woo, Oh, Byung-Chul, Kim, Seyun

“…Autophagy is a biological process that maintains cellular homeostasis and regulates the internal cellular environment. Hyperactivating autophagy to trigger…”
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Candesartan, an angiotensin-II receptor blocker, ameliorates insulin resistance and hepatosteatosis by reducing intracellular calcium overload and lipid accumulation by Lee, Jin Wook, Gu, Hyun-Oh, Jung, Yunshin, Jung, YunJae, Seo, Seung-Yong, Hong, Jeong-Hee, Hong, In-Sun, Lee, Dae Ho, Kim, Ok-Hee, Oh, Byung-Chul

“…Insulin resistance is a major contributor to the pathogenesis of several human diseases, including type 2 diabetes, hypertension, and hyperlipidemia. Notably,…”
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Cancers with Higher Density of Tumor-Associated Macrophages Were Associated with Poor Survival Rates by Jung, Kyong Yeun, Cho, Sun Wook, Kim, Young A, Kim, Daein, Oh, Byung-Chul, Park, Do Joon, Park, Young Joo

“…Macrophages are a component of a tumor's microenvironment and have various roles in tumor progression and metastasis. This study evaluated the relationships…”
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Isocitrate dehydrogenase 2 protects mice from high-fat diet-induced metabolic stress by limiting oxidative damage to the mitochondria from brown adipose tissue by Lee, Jae-Ho, Go, Younghoon, Kim, Do-Young, Lee, Sun Hee, Kim, Ok-Hee, Jeon, Yong Hyun, Kwon, Taeg Kyu, Bae, Jae-Hoon, Song, Dae-Kyu, Rhyu, Im Joo, Lee, In-Kyu, Shong, Minho, Oh, Byung-Chul, Petucci, Christopher, Park, Jeen-Woo, Osborne, Timothy F., Im, Seung-Soon

“…Isocitrate dehydrogenase 2 (IDH2) is an NADP + -dependent enzyme that catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate in the…”
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High-resolution structures of annexin A5 in a two-dimensional array by Hong, Seokho, Na, Soohui, Kim, Ok-Hee, Jeong, Soyeon, Oh, Byung-Chul, Ha, Nam-Chul

“…[Display omitted] •The crystal structures of human annexin A5 in its 2D array conformation were determined.•Structural analyses suggest conformational changes…”
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High-phytate/low-calcium diet is a risk factor for crystal nephropathies, renal phosphate wasting, and bone loss by Kim, Ok-Hee, Booth, Carmen J, Choi, Han Seok, Lee, Jinwook, Kang, Jinku, Hur, June, Jung, Woo Jin, Jung, Yun-Shin, Choi, Hyung Jin, Kim, Hyeonjin, Auh, Joong-Hyuck, Kim, Jung-Wan, Cha, Ji-Young, Lee, Young Jae, Lee, Cheol Soon, Choi, Cheolsoo, Jung, Yun Jae, Yang, Jun-Young, Im, Seung-Soon, Lee, Dae Ho, Cho, Sun Wook, Kim, Young-Bum, Park, Kyong Soo, Park, Young Joo, Oh, Byung-Chul

“…Phosphate overload contributes to mineral bone disorders that are associated with crystal nephropathies. Phytate, the major form of phosphorus in plant seeds,…”
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CXCL16 signaling mediated macrophage effects on tumor invasion of papillary thyroid carcinoma by Cho, Sun Wook, Kim, Young A, Sun, Hyun Jin, Kim, Ye An, Oh, Byung-Chul, Yi, Ka Hee, Park, Do Joon, Park, Young Joo

“…Macrophages in tumor microenvironment have pivotal roles in tumor growth, metastasis, and angiogenesis. We investigated the interacting mechanism of macrophage…”
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Leptin Elongates Hypothalamic Neuronal Cilia via Transcriptional Regulation and Actin Destabilization by Kang, Gil Myoung, Han, Yu Mi, Ko, Hyuk Whan, Kim, Joon, Oh, Byung Chul, Kwon, Ijoo, Kim, Min-Seon

“…Terminally differentiated neurons have a single, primary cilium. The primary cilia of hypothalamic neurons play a critical role in sensing metabolic signals…”
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TLR7-dependent eosinophil degranulation links psoriatic skin inflammation to small intestinal inflammatory changes in mice by Kim, Hee Joo, Jang, Jinsun, Na, Kunhee, Lee, Eun-Hui, Gu, Hyeon-Jung, Lim, Yoon Hee, Joo, Seul-A, Baek, Seung Eun, Roh, Joo-Young, Maeng, Han-Joo, Kim, Yun Hak, Lee, Young-Jae, Oh, Byung-Chul, Jung, YunJae

“…Recent evidence of gut microbiota dysbiosis in the context of psoriasis and the increased cooccurrence of inflammatory bowel disease and psoriasis suggest a…”
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Development of a novel testis-on-a-chip that demonstrates reciprocal crosstalk between Sertoli and Leydig cells in testicular tissue by Park, Se-Ra, Kook, Myung Geun, Kim, Soo-Rim, Lee, Choon-Mi, Lee, Jin Woo, Park, Jung-Kyu, Park, Chan Hum, Oh, Byung-Chul, Jung, YunJae, Hong, In-Sun

“…The reciprocal crosstalk between testicular Sertoli and Leydig cells plays a vital role in supporting germ cell development and maintaining testicular…”
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Unveiling the potential effects of acetylsalicylic acid: insights into regeneration in endometrial stem cells by Park, Se-Ra, Kim, Soo-Rim, Min, Eun-Kyung, Oh, Byung-Chul, Jung, YunJae, Kim, Yong Ho, Lee, Hwa-Yong

“…Abstract Background Although acetylsalicylic acid has been widely used for decades to treat and prevent various diseases, its potential effects on endometrial…”
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Crystal structure of the VanR transcription factor and the role of its unique α‐helix in effector recognition by Kwak, Yun Mi, Park, Sun Cheol, Na, Hye‐won, Kang, Seung Goo, Lee, Geun‐Shik, Ko, Hyun‐Jeong, Kim, Pyeung‐Hyeun, Oh, Byung‐Chul, Yoon, Sung‐il

“…VanR is a negative transcriptional regulator of bacteria that belongs to the PadR family and modulates the expression of vanillate transport and degradation…”
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Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling by Huang, Hu, Kong, Dong, Byun, Kyung Hee, Ye, Chianping, Koda, Shuichi, Lee, Dae Ho, Oh, Byung-Chul, Lee, Sam W, Lee, Bonghee, Zabolotny, Janice M, Kim, Min Seon, Bjørbæk, Christian, Lowell, Bradford B, Kim, Young-Bum

“…Leptin regulates energy balance. The authors show that Rho-kinase 1 (ROCK1) regulates leptin signaling by increasing activation of signaling molecules…”
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Exploring Memory Function Beyond Immune Cells: ANGPTL4‐Mediated Memory Functions in Tissue Resident Stem Cells by Park, Se‐Ra, Min, Eun‐kyung, Kim, Soo‐Rim, Kim, Suk‐Kyung, Na, Kun‐Hee, Park, Chan Hum, Jung, YunJae, Oh, Byung‐Chul, Hong, In‐Sun

“…Adapted immune cells are known to develop memory functions that increase resistance to subsequent infections after initial pathogen exposure, however, it is…”
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Bone Morphogenetic Protein-2 Stimulates Runx2 Acetylation by Jeon, Eun-Joo, Lee, Kwang-Youl, Choi, Nam-Sook, Lee, Mi-Hye, Kim, Hyun-Nam, Jin, Yun-Hye, Ryoo, Hyun-Mo, Choi, Je-Yong, Yoshida, Minoru, Nishino, Norikazu, Oh, Byung-Chul, Lee, Kyeong-Sook, Lee, Yong Hee, Bae, Suk-Chul

“…Runx2/Cbfa1/Pebp2aA is a global regulator of osteogenesis and is crucial for regulating the expression of bone-specific genes. Runx2 is a major target of the…”
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