Search Results - "Chugani, Harry T."

Metabolic costs and evolutionary implications of human brain development by Kuzawa, Christopher W., Chugani, Harry T., Grossman, Lawrence I., Lipovich, Leonard, Muzik, Otto, Hof, Patrick R., Wildman, Derek E., Sherwood, Chet C., Leonard, William R., Lange, Nicholas

“…Significance The metabolic costs of brain development are thought to explain the evolution of humans’ exceptionally slow and protracted childhood growth;…”
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Surgical treatment for refractory epileptic spasms: The Detroit series by Chugani, Harry T., Ilyas, Mohammed, Kumar, Ajay, Juhász, Csaba, Kupsky, William J., Sood, Sandeep, Asano, Eishi

“…Summary Objective We reviewed our experience of surgery for epileptic spasms (ES) with or without history of infantile spasms. Methods Data were reviewed from…”
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Statistical mapping of ictal high‐frequency oscillations in epileptic spasms by Nariai, Hiroki, Nagasawa, Tetsuro, Juhász, Csaba, Sood, Sandeep, Chugani, Harry T., Asano, Eishi

“…Summary Purpose:  We assessed 636 epileptic spasms seen in 11 children (median 44 spasms per child) and determined the spatial and temporal characteristics of…”
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Abnormal Brain Connectivity in Children After Early Severe Socioemotional Deprivation: A Diffusion Tensor Imaging Study by Eluvathingal, Thomas J, Chugani, Harry T, Behen, Michael E, Juhasz, Csaba, Muzik, Otto, Maqbool, Mohsin, Chugani, Diane C, Makki, Malek

“…We previously reported that children who were subjected to early socioemotional deprivation in Romanian orphanages showed glucose hypometabolism in limbic and…”
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Role of subdural electrocorticography in prediction of long-term seizure outcome in epilepsy surgery by Asano, Eishi, Juhász, Csaba, Shah, Aashit, Sood, Sandeep, Chugani, Harry T.

“…Since prediction of long-term seizure outcome using preoperative diagnostic modalities remains suboptimal in epilepsy surgery, we evaluated whether interictal…”
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Corpus Callosotomy for Intractable Epilepsy Revisited: The Children’s Hospital of Michigan Series by Luat, Aimee F., Asano, Eishi, Kumar, Ajay, Chugani, Harry T., Sood, Sandeep

“…Corpus callosotomy is a palliative procedure performed to reduce the severity of drug-resistant epilepsy. The authors assessed its efficacy on different…”
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Evolution of Surgical Management for Intractable Epileptic Spasms by Rashid, Salman, MD, Chugani, Harry T, MD

“…The author will have to provide one…”
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A distinct microRNA expression profile is associated with α[11C]-methyl-L-tryptophan (AMT) PET uptake in epileptogenic cortical tubers resected from patients with tuberous sclerosis complex by Bagla, Shruti, Cukovic, Daniela, Asano, Eishi, Sood, Sandeep, Luat, Aimee, Chugani, Harry T., Chugani, Diane C., Dombkowski, Alan A.

“…Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in various organs and arises due to mutations in the TSC1 or TSC2 genes. TSC…”
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TLR7 activation in epilepsy of tuberous sclerosis complex by Dombkowski, Alan A., Cukovic, Daniela, Bagla, Shruti, Jones, McKenzie, Caruso, Joseph A., Chugani, Harry T., Chugani, Diane C.

“…Background Neuroinflammation and toll-like receptors (TLR) of the innate immune system have been implicated in epilepsy. We previously reported high levels of…”
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Developmental Changes in the Transcriptome of Human Cerebral Cortex Tissue: Long Noncoding RNA Transcripts by Lipovich, Leonard, Tarca, Adi L., Cai, Juan, Jia, Hui, Chugani, Harry T., Sterner, Kirstin N., Grossman, Lawrence I., Uddin, Monica, Hof, Patrick R., Sherwood, Chet C., Kuzawa, Christopher W., Goodman, Morris, Wildman, Derek E.

“…The human neocortex is characterized by protracted developmental intervals of synaptogenesis and myelination, which allow for an extended period of learning…”
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Predictors of Cognitive Functions in Children With Sturge–Weber Syndrome: A Longitudinal Study by Bosnyák, Edit, MD, Behen, Michael E., PhD, Guy, William C., PhD, Asano, Eishi, MD, PhD, Chugani, Harry T., MD, Juhász, Csaba, MD, PhD

“…Abstract Background Sturge–Weber syndrome is often accompanied by seizures and neurocognitive deterioration, although previous studies have suggested that…”
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Transient focal cortical increase of interictal glucose metabolism in Sturge‐Weber syndrome: Implications for epileptogenesis by Alkonyi, Bálint, Chugani, Harry T., Juhász, Csaba

“…Summary Purpose:  To investigate clinical correlates and longitudinal course of interictal focal cortical glucose hypermetabolism in children with Sturge‐Weber…”
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Local Brain Functional Activity Following Early Deprivation: A Study of Postinstitutionalized Romanian Orphans by Chugani, Harry T., Behen, Michael E., Muzik, Otto, Juhász, Csaba, Nagy, Ferenc, Chugani, Diane C.

“…Early global deprivation of institutionalized children may result in persistent specific cognitive and behavioral deficits. In order to examine brain…”
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Hypermetabolism on Pediatric PET Scans of Brain Glucose Metabolism: What Does It Signify? by Chugani, Harry T

“…When one is interpreting clinical F-FDG PET scans of the brain (excluding tumors) in children, the typical abnormality seen is hypometabolism of various brain…”
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Post-Traumatic Epilepsy in Children—Experience From a Tertiary Referral Center by Park, Jun T., MD, Chugani, Harry T., MD

“…Abstract Background Post-traumatic epilepsy after a traumatic brain injury occurs in 10%-20% of children. Unfortunately, a biomarker that could provide…”
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Short-latency median-nerve somatosensory-evoked potentials and induced gamma-oscillations in humans by Fukuda, Miho, Nishida, Masaaki, Juhász, Csaba, Muzik, Otto, Sood, Sandeep, Chugani, Harry T., Asano, Eishi

“…Recent studies have suggested that cortical gamma-oscillations are tightly linked with various forms of physiological activity. In the present study, the…”
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Origin and Propagation of Epileptic Spasms Delineated on Electrocorticography by Asano, Eishi, Juhász, Csaba, Shah, Aashit, Muzik, Otto, Chugani, Diane C., Shah, Jagdish, Sood, Sandeep, Chugani, Harry T.

“…Purpose: Ictal electrographic changes were analyzed on intracranial electrocorticography (ECoG) in children with medically refractory epileptic spasms to…”
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Congruence of happy and sad emotion in music and faces modifies cortical audiovisual activation by Jeong, Jeong-Won, Diwadkar, Vaibhav A., Chugani, Carla D., Sinsoongsud, Piti, Muzik, Otto, Behen, Michael E., Chugani, Harry T., Chugani, Diane C.

“…The powerful emotion inducing properties of music are well-known, yet music may convey differing emotional responses depending on environmental factors. We…”
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In Memoriam: Charles Kennedy (August 27, 1920, to October 6, 2015) by Chugani, Harry T., MD, Lavenstein, Bennett, MD

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Dynamic gene expression in the human cerebral cortex distinguishes children from adults by Sterner, Kirstin N, Weckle, Amy, Chugani, Harry T, Tarca, Adi L, Sherwood, Chet C, Hof, Patrick R, Kuzawa, Christopher W, Boddy, Amy M, Abbas, Asad, Raaum, Ryan L, Grégoire, Lucie, Lipovich, Leonard, Grossman, Lawrence I, Uddin, Monica, Goodman, Morris, Wildman, Derek E

“…In comparison with other primate species, humans have an extended juvenile period during which the brain is more plastic. In the current study we sought to…”
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