Search Results - "Chuang, Eric Y."
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1
Altered gut microbiota and inflammatory cytokine responses in patients with Parkinson's disease
Published in Journal of neuroinflammation (27-06-2019)“…Emerging evidence suggests that gut microbiome composition alterations affect neurodegeneration through neuroinflammation in the pathogenesis of Parkinson's…”
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2
miRSystem: an integrated system for characterizing enriched functions and pathways of microRNA targets
Published in PloS one (01-08-2012)“…Many prediction tools for microRNA (miRNA) targets have been developed, but inconsistent predictions were observed across multiple algorithms, which can make…”
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3
Hypoxia-Induced MALAT1 Promotes the Proliferation and Migration of Breast Cancer Cells by Sponging MiR-3064-5p
Published in Frontiers in oncology (03-05-2021)“…Hypoxia, a common process during tumor growth, can lead to tumor aggressiveness and is tightly associated with poor prognosis. Long noncoding RNAs (lncRNAs)…”
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4
Identification of a Novel Biomarker, SEMA5A, for Non―Small Cell Lung Carcinoma in Nonsmoking Women
Published in Cancer epidemiology, biomarkers & prevention (01-10-2010)“…Although cigarette smoking is the major risk factor for lung cancer, only 7% of female lung cancer patients in Taiwan have a history of smoking. The genetic…”
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5
CLIN_SKAT: an R package to conduct association analysis using functionally relevant variants
Published in BMC bioinformatics (23-10-2022)“…Abstract Background Availability of next generation sequencing data, allows low-frequency and rare variants to be studied through strategies other than the…”
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6
Twnbiome: a public database of the healthy Taiwanese gut microbiome
Published in BMC bioinformatics (14-12-2023)“…With new advances in next generation sequencing (NGS) technology at reduced costs, research on bacterial genomes in the environment has become affordable…”
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7
Discovery and prioritization of genetic determinants of kidney function in 297,355 individuals from Taiwan and Japan
Published in Nature communications (29-10-2024)“…Current genome-wide association studies (GWAS) for kidney function lack ancestral diversity, limiting the applicability to broader populations. The East-Asian…”
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8
Deregulated microRNAs in triple-negative breast cancer revealed by deep sequencing
Published in Molecular cancer (10-02-2015)“…MicroRNAs (miRNAs) are short, non-coding RNA molecules that play critical roles in human malignancy. However, the regulatory characteristics of miRNAs in…”
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9
Inhibition of DNMTs increases neoantigen-reactive T-cell toxicity against microsatellite-stable colorectal cancer in combination with radiotherapy
Published in Biomedicine & pharmacotherapy (01-08-2024)“…The therapeutic efficacy of immunotherapy is limited in the majority of colorectal cancer patients due to the low mutational and neoantigen burdens in this…”
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10
anamiR: integrated analysis of MicroRNA and gene expression profiling
Published in BMC bioinformatics (14-05-2019)“…With advancements in high-throughput technologies, the cost of obtaining expression profiles of both mRNA and microRNA in the same individual has substantially…”
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Predicting Breast Cancer Gene Expression Signature by Applying Deep Convolutional Neural Networks From Unannotated Pathological Images
Published in Frontiers in oncology (01-12-2021)“…We proposed a highly versatile two-step transfer learning pipeline for predicting the gene signature defining the intrinsic breast cancer subtypes using…”
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12
A risk prediction model of gene signatures in ovarian cancer through bagging of GA-XGBoost models
Published in Journal of advanced research (01-05-2021)“…[Display omitted] Ovarian cancer (OC) is one of the most frequent gynecologic cancers among women, and high-accuracy risk prediction techniques are essential…”
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13
Development of a Gene-Based Prediction Model for Recurrence of Colorectal Cancer Using an Ensemble Learning Algorithm
Published in Frontiers in oncology (22-02-2021)“…It is difficult to determine which patients with stage I and II colorectal cancer are at high risk of recurrence, qualifying them to undergo adjuvant…”
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14
Concurrent gene signatures for han chinese breast cancers
Published in PloS one (03-10-2013)“…The interplay between copy number variation (CNV) and differential gene expression may be able to shed light on molecular process underlying breast cancer and…”
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15
Molecular characteristics and metastasis predictor genes of triple-negative breast cancer: a clinical study of triple-negative breast carcinomas
Published in PloS one (25-09-2012)“…Triple-negative breast cancer is a subtype of breast cancer with aggressive tumor behavior and distinct disease etiology. Due to the lack of an effective…”
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16
Comparison of DNA stabilizers and storage conditions on preserving fecal microbiota profiles
Published in Journal of the Formosan Medical Association (01-12-2020)“…Appropriate storage of fecal samples is a critical step for the unbiased analysis of microbial communities in metagenomic studies. Rapid freezing at −80 °C is…”
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17
Regulatory mechanisms and function of hypoxia-induced long noncoding RNA NDRG1-OT1 in breast cancer cells
Published in Cell death & disease (20-09-2022)“…Hypoxia is a classic feature of the tumor microenvironment that has profound effects on cancer progression and is tightly associated with poor prognosis. Long…”
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18
Exposure-associated DNA methylation among people exposed to multiple industrial pollutants
Published in Clinical epigenetics (20-08-2024)“…Current research on the epigenetic repercussions of exposure to a combination of pollutants is limited. This study aims to discern DNA methylation probes…”
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Join Classifier of Type and Index Mutation on Lung Cancer DNA Using Sequential Labeling Model
Published in IEEE access (2022)“…The sequential labeling model is commonly used for time series or sequence data where each instance label is classified using previous instance label. In this…”
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20
High-sensitivity in vivo THz transmission imaging of early human breast cancer in a subcutaneous xenograft mouse model
Published in Optics express (24-10-2011)“…We performed in vivo THz transmission imaging study on a subcutaneous xenograft mouse model for early human breast cancer detection. With a THz-fiber-scanning…”
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