Search Results - "Chua, Melvin L.K"

A Prostate Cancer “ Nimbosus ”: Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies by Chua, Melvin L.K, Lo, Winnie, Pintilie, Melania, Murgic, Jure, Lalonde, Emilie, Bhandari, Vinayak, Mahamud, Osman, Gopalan, Anuradha, Kweldam, Charlotte F, van Leenders, Geert J.L.H, Verhoef, Esther I, Hoogland, Agnes Marije, Livingstone, Julie, Berlin, Alejandro, Dal Pra, Alan, Meng, Alice, Zhang, Junyan, Orain, Michèle, Picard, Valérie, Hovington, Hélène, Bergeron, Alain, Lacombe, Louis, Fradet, Yves, Têtu, Bernard, Reuter, Victor E, Fleshner, Neil, Fraser, Michael, Boutros, Paul C, van der Kwast, Theodorus H, Bristow, Robert G

“…Abstract Background Intraductal carcinoma (IDC) and cribriform architecture (CA) represent unfavorable subpathologies in localized prostate cancer. We recently…”
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Intraductal Carcinoma of the Prostate: Anonymous to Ominous by Chua, Melvin L.K, van der Kwast, Theodorus H, Bristow, Robert G

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The evolution of Epstein-Barr virus detection in nasopharyngeal carcinoma by Li, You Quan, Khin, Ni Sann, Chua, Melvin L K

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A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID‐19) Pandemic: An International Collaborative Group by Al‐Shamsi, Humaid O., Alhazzani, Waleed, Alhuraiji, Ahmad, Coomes, Eric A., Chemaly, Roy F., Almuhanna, Meshari, Wolff, Robert A., Ibrahim, Nuhad K., Chua, Melvin L.K., Hotte, Sebastien J., Meyers, Brandon M., Elfiki, Tarek, Curigliano, Giuseppe, Eng, Cathy, Grothey, Axel, Xie, Conghua

“…The outbreak of coronavirus disease 2019 (COVID‐19) has rapidly spread globally since being identified as a public health emergency of major international…”
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The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression by Espiritu, Shadrielle Melijah G., Liu, Lydia Y., Rubanova, Yulia, Bhandari, Vinayak, Holgersen, Erle M., Szyca, Lesia M., Fox, Natalie S., Chua, Melvin L.K., Yamaguchi, Takafumi N., Heisler, Lawrence E., Livingstone, Julie, Wintersinger, Jeff, Yousif, Fouad, Lalonde, Emilie, Rouette, Alexandre, Salcedo, Adriana, Houlahan, Kathleen E., Li, Constance H., Huang, Vincent, Fraser, Michael, van der Kwast, Theodorus, Morris, Quaid D., Bristow, Robert G., Boutros, Paul C.

“…The majority of newly diagnosed prostate cancers are slow growing, with a long natural life history. Yet a subset can metastasize with lethal consequences. We…”
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A Radiomics Model for Predicting the Response to Bevacizumab in Brain Necrosis after Radiotherapy by Cai, Jinhua, Zheng, Junjiong, Shen, Jun, Yuan, Zhiyong, Xie, Mingwei, Gao, Miaomiao, Tan, Hongqi, Liang, Zhongguo, Rong, Xiaoming, Li, Yi, Li, Honghong, Jiang, Jingru, Zhao, Huiying, Argyriou, Andreas A, Chua, Melvin L K, Tang, Yamei

“…Bevacizumab is considered a promising therapy for brain necrosis after radiotherapy, while some patients fail to derive benefit or even worsen. Hence, we…”
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International Recommendations on Reirradiation by Intensity Modulated Radiation Therapy for Locally Recurrent Nasopharyngeal Carcinoma by Ng, Wai Tong, Soong, Yoke Lim, Ahn, Yong Chan, AlHussain, Hussain, Choi, Horace C.W., Corry, June, Grégoire, Vincent, Harrington, Kevin J., Hu, Chao Su, Jensen, Kenneth, Kwong, Dora L., Langendijk, Johannes A., Le, Quynh Thu, Lee, Nancy Y., Lin, Jin Ching, Lu, Tai Xiang, Mendenhall, William M., O’Sullivan, Brian, Ozyar, Enis, Pan, Jian Ji, Peters, Lester J., Poh, Sharon S., Rosenthal, David I., Sanguineti, Giuseppe, Tao, Yungan, Wee, Joseph T., Yom, Sue S., Chua, Melvin L.K., Lee, Anne W.M.

“…Reirradiation for locally recurrent nasopharyngeal carcinoma (NPC) is challenging because prior radiation dose delivered in the first course is often close to…”
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Multidisciplinary team meetings — challenges of implementation science by Iyer, N. Gopalakrishna, Chua, Melvin L. K.

“…Multidisciplinary team meetings have several flaws; herein, we propose approaches for cancer centres to transform these limitations into improvements in the…”
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A nomogram to predict symptomatic epilepsy in patients with radiation-induced brain necrosis by Huang, Xiaolong, Zhang, Xiaoni, Wang, Xicheng, Rong, Xiaoming, Li, Yi, Li, Honghong, Jiang, Jingru, Cai, Jinhua, Zhuo, Xiaohuang, Pi, Yaxuan, Lin, Jinpeng, Chua, Melvin L.K., Argyriou, Andreas A., Lattanzi, Simona, Simone, Charles B., Glass, Jon, Palmer, Joshua D., Chow, Edward, Brown, Paul D., Yue, Zongwei, Tang, Yamei

“…OBJECTIVETo develop and validate a nomogram to predict epilepsy in patients with radiation-induced brain necrosis (RN). METHODSThe nomogram was based on a…”
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Surgery as an alternative to radiotherapy in early‐stage nasopharyngeal carcinoma: innovation at the expense of uncertainty by Huang, Luo, Chua, Melvin L.K.

“…[...]to human papilloma virus-associated oropharyngeal squamous cell carcinoma, Epstein-Barr virus (EBV)-associated NPC is exquisitely sensitive to RT…”
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Improved outcomes with dose escalation in localized prostate cancer treated with precision image-guided radiotherapy by Raziee, Hamid, Moraes, Fabio Y, Murgic, Jure, Chua, Melvin L.K, Pintilie, Melania, Chung, Peter, Ménard, Cynthia, Bayley, Andrew, Gospodarowicz, Mary, Warde, Padraig, Craig, Tim, Catton, Charles, Bristow, Robert G, Jaffray, David A, Berlin, Alejandro

“…Abstract Background and purpose Dose-escalated radiotherapy (DE) improves outcomes in localized prostate cancer (PCa). The impact of DE in the context of…”
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Targeting DNA Repair for Precision Radiotherapy – Balancing the Therapeutic Ratio by Mahamud, Osman, So, Jonathan, Chua, Melvin L.K, Bristow, Robert G

“…Abstract Genomic instability is underpinned by defects in the DNA damage response (DDR) and DNA repair pathways. Subsequent clonal selection and adaption can…”
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Clinical outcomes of coronavirus disease 2019 (COVID‐19) in cancer patients with prior exposure to immune checkpoint inhibitors by Wu, Qiuji, Chu, Qian, Zhang, Hongyan, Yang, Bin, He, Xudong, Zhong, Yahua, Yuan, Xianglin, Chua, Melvin L.K., Xie, Conghua

“…Abbreviations COVID-19 coronavirus disease 2019 CTLA-4 cytotoxic T-lymphocyte-associated protein 4 ICI immune checkpoint inhibitor IL-6 interleukin-6 PD-1…”
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Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study by Miao, Jingjing, Wang, Lin, Ong, Enya H.W., Hu, Chaosu, Lin, Shaojun, Chen, Xiaozhong, Chen, Yuanyuan, Zhong, Yahua, Jin, Feng, Lin, Qin, Lin, Shaomin, Hu, Xuefeng, Zhang, Ning, Wang, Rensheng, Wang, Cong, Guo, Xiang, Yit, Nelson L.F., Shi, Hanping, Tan, Sze Huey, Mai, Haiqiang, Xie, Conghua, Chua, Melvin L.K., Zhao, Chong

“…Background Induction chemotherapy (IC) and concurrent chemoradiotherapy (CCRT) is the standard of care for locoregionally advanced nasopharyngeal carcinoma…”
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Particle beam therapy for nasopharyngeal cancer: A systematic review and meta-analysis by Ng, Wai Tong, But, Barton, Wong, Charlene H.L., Choi, Cheuk-Wai, Chua, Melvin L.K., Blanchard, Pierre, Lee, Anne W.M.

“…•Particle beam therapy yields excellent short-term treatment outcomes among NPC patients.•Particle beam therapy is generally safe in primary and recurrent NPC…”
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Corrigendum to “Surveillance one year post focal cryotherapy for clinically significant prostate cancer using mpMRI and PIRADS v2.1: An initial experience from a prospective phase II mandatory biopsy study” [Eur. J. Radiol. Open 11 (2023) 100529] by Velaga, Jyothirmayi, Tay, Kae Jack, Hang, Guanqi, Tan, Yu Guang, Yuen, John S.P., Chua, Melvin L.K., Gupta, Rajan T., Polascik, Thomas J., Ngo, Nye Thane, Law, Yan Mee

“…[This corrects the article DOI: 10.1016/j.ejro.2023.100529.]…”
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Correlation between DNA damage responses of skin to a test dose of radiation and late adverse effects of earlier breast radiotherapy by Somaiah, Navita, Chua, Melvin L.K, Bourne, Sara, Daley, Frances, A’ Hern, Roger, Nuta, Otilia, Gothard, Lone, Boyle, Sue, Herskind, Carsten, Pearson, Ann, Warrington, Jim, Helyer, Sarah, Owen, Roger, Rothkamm, Kai, Yarnold, John

“…Abstract Aim To correlate residual double strand breaks (DSB) 24 h after 4 Gy test doses to skin in vivo and to lymphocytes in vitro with adverse effects of…”
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ASCO's Leadership Development Program: Focusing on the Next Generation of Leaders in Asia Pacific by de Guzman, Roselle B, Chua, Melvin L K, Goldstein, David, Aung, Soe, Eaton, Vanessa, Park, Keunchil

“…The demand for high-quality and more comprehensive oncology care will continue to rise globally. Effective leadership is particularly important. The evolving…”
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Challenges and Opportunities With the Use of Hypofractionated Radiation Therapy in Cancer Care: Regional Perspectives From South Korea, Japan, Singapore, and Australia by Akimoto, Tetsuo, Aoyama, Hidefumi, Chua, Melvin L.K., Jayamanne, Dasantha, Mizowaki, Takashi, Morris, Lucinda, Onishi, Hiroshi, Song, Si Yeol, Zeidan, Youssef H., Sharma, Ricky A.

“…Hypofractionated radiotherapy schedules provide higher per-fraction radiation doses delivered in fewer fractions than conventional schedules. This novel…”
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Development of a risk classification system combining TN-categories and circulating EBV DNA for non-metastatic NPC in 10,149 endemic cases by Chen, Fo-Ping, Lin, Li, Liang, Jin-Hui, Tan, Sze Huey, Ong, Enya H.W., Luo, Ying-Shan, Huang, Luo, Sim, Adelene Y.L., Wang, Hai-Tao, Gao, Tian-Sheng, Deng, Bin, Zhou, Guan-Qun, Kou, Jia, Chua, Melvin L.K., Sun, Ying

“…Background: The objective of this study was to construct a risk classification system integrating cell-free Epstein-Barr virus (cfEBV) DNA with T- and N-…”
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