Search Results - "Chu, Xingkun"
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Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer’s disease progression
Published in Cell research (01-10-2019)“…Recently, increasing evidence has suggested the association between gut dysbiosis and Alzheimer’s disease (AD) progression, yet the role of gut microbiota in…”
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Chronic Kidney Disease and Cognitive Impairment: The Kidney-Brain Axis
Published in Kidney diseases (01-07-2022)“…Background: Cognitive impairment, increasingly recognized as a major social burden, is commonly found in chronic kidney disease (CKD) patients. Summary:…”
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Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
Published in Journal of translational medicine (01-11-2024)“…Background Neuromyelitis optica spectrum disorders (NMOSD) are autoimmune conditions that affect the central nervous system. The contribution of peripheral…”
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Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification
Published in Frontiers in pharmacology (27-08-2024)“…Multiple sclerosis (MS), a chronic autoimmune disorder marked by demyelination in the central nervous system, is exceptionally uncommon in China, and remains…”
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Induced dopaminergic neurons: A new promise for Parkinson’s disease
Published in Redox biology (01-04-2017)“…Motor symptoms that define Parkinson’s disease (PD) are caused by the selective loss of nigral dopaminergic (DA) neurons. Cell replacement therapy for PD has…”
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Structural characterization and in vitro anti-inflammatory estimation of an unusual pectin linked by rhamnogalacturonan I and xylogalacturonan from lotus plumule
Published in International journal of biological macromolecules (01-01-2022)“…A novel homogenous polysaccharide LPWF together with its three acid hydrolysis products LPWF1–3 were isolated and prepared from lotus plumule (germs of Nelumbo…”
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Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3β phosphorylation in a tau transgenic Drosophila model of Alzheimer's disease
Published in Translational neurodegeneration (29-11-2016)“…Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disease that causes substantial public health care burdens. Intensive efforts have…”
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GV‐971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities
Published in CNS neuroscience & therapeutics (01-07-2024)“…Aims Growing evidence suggests that an imbalanced gut microbiota composition plays a crucial role in the development of neuromyelitis optica spectrum disorders…”
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Neuroprotective effects of salidroside through PI3K/Akt pathway activation in Alzheimer's disease models
Published in Drug design, development and therapy (01-01-2016)“…Alzheimer's disease (AD) is a devastating neurodegenerative disorder characterized by deposits of aggregated amyloid-β (Aβ) peptide and neurofibrillary tangles…”
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Salidroside reduces tau hyperphosphorylation via up-regulating GSK-3Beta phosphorylation in a tau transgenic Drosophila model of Alzheimers disease
Published in Translational neurodegeneration (01-01-2016)“…Background Alzheimer's disease (AD) is an age-related and progressive neurodegenerative disease that causes substantial public health care burdens. Intensive…”
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Neuroprotective effects of salidroside through P13K/Akt pathway activation in Alzheimer's disease models
Published in Drug design, development and therapy (01-01-2016)Get full text
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