Search Results - "Chu, Xiaoqin"
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Formulation, production, in vitro release and in vivo pharmacokinetics of cinnamaldehyde sub-micron emulsions
Published in Pharmaceutical development and technology (02-07-2020)“…Objective: The purpose of this study was to study the effects of formulation of cinnamaldehyde submicron emulsion (CA-SME) and optimize the preparation process…”
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Study on the transdermal penetration mechanism of ibuprofen nanoemulsions
Published in Drug development and industrial pharmacy (04-03-2019)“…Objective: The purpose of this study was to research the mechanism of percutaneous penetration of Ibuprofen (IBU) nanoemulsion. Method: Transdermal penetration…”
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3
Hexagonal liquid crystalline system containing cinnamaldehyde for enhancement of skin permeation of sinomenine hydrochloride
Published in Pharmaceutical development and technology (03-07-2022)“…Sinomenine hydrochloride (SH) is usually applied to treat rheumatoid arthritis (RA) with severe side effects due to oral administration. Cinnamaldehyde (CA) as…”
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4
Cubic and hexagonal liquid crystal gels for ocular delivery with enhanced effect of pilocarpine nitrate on anti-glaucoma treatment
Published in Drug delivery (01-01-2019)“…The objective of this work was to investigate phytantriol-based liquid crystal (LC) gels including cubic (Q 2 ) and hexagonal (H 2 ) phase for ocular delivery…”
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5
Research on the quality markers of antioxidant activity of Kai-Xin-San based on the spectrum-effect relationship
Published in Frontiers in pharmacology (27-12-2023)“…Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern…”
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6
A Novel Phytantriol-Based In Situ Liquid Crystal Gel for Vaginal Delivery
Published in AAPS PharmSciTech (01-07-2019)“…The purpose of this paper was to evaluate the potential of in situ liquid crystal (LC) gels based on phytantriol (PYT) for vaginal delivery. The PYT-based in…”
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7
The in vitro intestinal cell model: different co-cultured cells create different applications
Published in Journal of drug targeting (01-06-2024)“…As a vitro absorption model, the Caco-2 cells originate from a human colon adenocarcinomas and can differentiate into a cell layer with enterocyte-like…”
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SEDDS facilitate cinnamaldehyde crossing the mucus barrier: The perspective of mucus and Caco-2/HT29 co-culture models
Published in International journal of pharmaceutics (25-02-2022)“…[Display omitted] Self-emulsifying drug delivery systems (SEDDS) have potential applications in the delivery of hydrophobic components. Oral drugs are readily…”
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Models to evaluate the barrier properties of mucus during drug diffusion
Published in International journal of pharmaceutics (15-04-2021)“…[Display omitted] Mucus is widely disseminated in the nasal cavity, oral cavity, respiratory tract, eyes, gastrointestinal tract, and reproductive tract to…”
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10
Pharmacodynamic and pharmacokinetic study of Shaoyao Gancao decoction for repairing intestinal barrier damage in ulcerative colitis
Published in Molecular immunology (01-11-2024)“…To study the therapeutic effect and mechanism of Shaoyao Gancao Decoction (SGD) on ulcerative colitis (UC) mice based on the perspective of intestinal barrier,…”
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11
Improved uptake and bioavailability of cinnamaldehyde via solid lipid nanoparticles for oral delivery
Published in Pharmaceutical development and technology (26-11-2022)“…The purpose of this experiment was to explore the effect of Solid lipid nanoparticles (SLNs) on improving the oral absorption and bioavailability of…”
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Preparation of cubic liquid crystal nanoparticles of puerarin and its protective effect on ischemic stroke
Published in Nanomedicine (01-11-2024)“…The low oral bioavailability of puerarin (Pur) affects its efficacy. Preparation of puerarin cubic liquid crystal nanoparticles (Pur-Cub) enhances the…”
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Characterization of Lipid-Based Lyotropic Liquid Crystal and Effects of Guest Molecules on Its Microstructure: a Systematic Review
Published in AAPS PharmSciTech (01-07-2018)“…Liquid crystals (LCs) are conventionally divided into thermotropic or lyotropic, based on the organization and sequence of the controlled molecular system…”
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14
In vitro and in vivo evaluation of cinnamaldehyde Microemulsion–Mucus interaction
Published in Journal of food biochemistry (01-10-2022)“…The current investigation explores the possible mechanism of the microemulsion drug delivery system to improve the oral bioavailability of cinnamaldehyde (CA),…”
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15
Cubic Liquid Crystalline Gels Based on Glycerol Monooleate for Intra-articular Injection
Published in AAPS PharmSciTech (01-02-2018)“…In situ gels containing sinomenine hydrochloride (SMH) for intra-articular (IA) administration to treat rheumatoid arthritis (RA) were designed and…”
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16
Construction of various lipid carriers to study the transdermal penetration mechanism of sinomenine hydrochloride
Published in Journal of microencapsulation (01-05-2024)“…To investigate the transdermal mechanisms and compare the differences in transdermal delivery of Sinomenine hydrochloride (SN) between solid lipid…”
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Exploring the pathogenesis of RA through the gut-articular axis-dysbiosis a potential factor
Published in Clinical anatomy (New York, N.Y.) (27-08-2024)“…Rheumatoid arthritis (RA) is a chronic autoimmune disease with a complex etiology. It has been suggested that the pathogenesis of RA begins in the mucosa and…”
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Liposome and microemulsion loaded with ibuprofen: from preparation to mechanism of drug transport
Published in Journal of microencapsulation (18-08-2022)“…To compare the difference between liposome (LP) and microemulsion (ME) in delivering ibuprofen (IBU) transdermally and explore relative mechanism. IBU-LP and…”
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Preparation, Synergism, and Biocompatibility of in situ Liquid Crystals Loaded with Sinomenine and 5-Fluorouracil for Treatment of Liver Cancer
Published in International journal of nanomedicine (01-01-2021)“…Transarterial chemoembolization is the preferred treatment for patients with middle and advanced-stage hepatocellular carcinoma (HCC); however, most hepatic…”
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20
Chinese herb couple against diabetes: integrating network pharmacology and mechanism study
Published in Journal of biomolecular structure & dynamics (12-02-2024)“…Cassia twig is a dry twig of , a plant. Astragalus L is one of the largest genuses of flowering plants in the family. Roots of A. membranaceus Bge. var…”
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