Search Results - "Chu, Uyen B"

The Oligomeric States of the Purified Sigma-1 Receptor Are Stabilized by Ligands by Gromek, Katarzyna A., Suchy, Fabian P., Meddaugh, Hannah R., Wrobel, Russell L., LaPointe, Loren M., Chu, Uyen B., Primm, John G., Ruoho, Arnold E., Senes, Alessandro, Fox, Brian G.

“…Sigma-1 receptor (S1R) is a mammalian member of the ERG2 and sigma-1 receptor-like protein family (pfam04622). It has been implicated in drug addiction and…”
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The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes by Chu, Uyen B., Mavlyutov, Timur A., Chu, Ming-Liang, Yang, Huan, Schulman, Amanda, Mesangeau, Christophe, McCurdy, Christopher R., Guo, Lian-Wang, Ruoho, Arnold E.

“…The sigma-2 receptor (S2R) is a potential therapeutic target for cancer and neuronal diseases. However, the identity of the S2R has remained a matter of…”
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Endothelial protective genes induced by statin are mimicked by ERK5 activation as triggered by a drug combination of FTI-277 and GGTI-298 by Chu, Uyen B., Duellman, Tyler, Weaver, Sara J., Tao, Yunting, Yang, Jay

“…Statins are potent inhibitors of cholesterol biosynthesis and are clinically beneficial in preventing cardiovascular diseases, however, the therapeutic utility…”
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The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines by Ruoho, Arnold E, Chu, Uyen B, Ramachandran, Subramaniam, Fontanilla, Dominique, Mavlyutov, Timur, Hajipour, Abdol R

“…The sigma-1 receptor is a 26 kDa endoplasmic reticulum resident membrane protein that has been shown to have chaperone activity in addition to its promiscuous…”
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Sigma Receptor Binding Assays by Chu, Uyen B, Ruoho, Arnold E

“…Sigma receptors, both Sigma-1(S1R) and Sigma-2 (S2R), are small molecule-regulated, primarily endoplasmic reticulum (ER) membrane-associated sites. A number of…”
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Biochemical Pharmacology of the Sigma-1 Receptor by Chu, Uyen B, Ruoho, Arnold E

“…The sigma-1 receptor (S1R) is a 223 amino acid two transmembrane (TM) pass protein. It is a non-ATP-binding nonglycosylated ligand-regulated molecular…”
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Photoaffinity Labeling of the Sigma‑1 Receptor with N‑[3-(4-Nitrophenyl)propyl]‑N‑dodecylamine: Evidence of Receptor Dimers by Chu, Uyen B, Ramachandran, Subramaniam, Hajipour, Abdol R, Ruoho, Arnold E

“…The sigma-1 receptor is a ligand-regulated endoplasmic reticulum (ER) resident chaperone involved in the maintenance of cellular homeostasis. Coupling of the…”
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Noncompetitive Inhibition of Indolethylamine‑N‑methyltransferase by N,N‑Dimethyltryptamine and N,N‑Dimethylaminopropyltryptamine by Chu, Uyen B, Vorperian, Sevahn K, Satyshur, Kenneth, Eickstaedt, Kelsey, Cozzi, Nicholas V, Mavlyutov, Timur, Hajipour, Abdol R, Ruoho, Arnold E

“…Indolethylamine-N-methyltransferase (INMT) is a Class 1 transmethylation enzyme known for its production of N,N-dimethyltryptamine (DMT), a hallucinogen with…”
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The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids by Ramachandran, Subramaniam, Chu, Uyen B., Mavlyutov, Timur A., Pal, Arindam, Pyne, Susan, Ruoho, Arnold E.

“…The sigma1 receptor is distinguished for its ability to bind various pharmacological agents including drugs of abuse such as cocaine and methamphetamine. Some…”
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Identification of regions of the sigma-1 receptor ligand binding site using a novel photoprobe by Pal, Arindam, Hajipour, Abdol R, Fontanilla, Dominique, Ramachandran, Subramaniam, Chu, Uyen B, Mavlyutov, Timur, Ruoho, Arnold E

“…sigma Receptors, once considered a class of opioid receptors, are now regarded as a unique class of receptors that contain binding sites for a wide range of…”
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Juxtaposition of the Steroid Binding Domain-like I and II Regions Constitutes a Ligand Binding Site in the σ-1 Receptor by Pal, Arindam, Chu, Uyen B., Ramachandran, Subramaniam, Grawoig, David, Guo, Lian-Wang, Hajipour, Abdol R., Ruoho, Arnold E.

“…σ-1 receptors represent unique binding sites that are capable of interacting with a wide range of compounds to mediate different cellular events. The…”
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Probing the Steroid Binding Domain-like I (SBDLI) of the Sigma-1 Receptor Binding Site Using N-Substituted Photoaffinity Labels by Fontanilla, Dominique, Hajipour, Abdol R, Pal, Arindam, Chu, Uyen B, Arbabian, Marty, Ruoho, Arnold E

“…Radioiodinated photoactivatable photoprobes can provide valuable insights regarding protein structure. Previous work in our laboratory showed that the cocaine…”
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Characterization of Interactions of 4-Nitrophenylpropyl-N-alkylamine with Sigma Receptors by Chu, Uyen B, Hajipour, Abdol R, Ramachandran, Subramaniam, Ruoho, Arnold E

“…Sigma receptors are small membrane proteins implicated in a number of pathophysiological conditions, including drug addiction, psychosis, and cancer; thus,…”
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Synthesis and characterization of N,N-dialkyl and N-alkyl- N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors by Hajipour, Abdol R., Fontanilla, Dominique, Chu, Uyen B., Arbabian, Marty, Ruoho, Arnold E.

“…The sigma-1 receptor is a unique non-opioid, non-PCP binding site that has been implicated in many different pathophysiological conditions including psychosis,…”
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In vitro interaction of tubulin with the photoreceptor cGMP phosphodiesterase γ-subunit by Chu, Uyen B., Song, Jikui, Mavlyutov, Timur A., Guo, Lian-Wang

“…The α and β tubulins compose the microtubule cytoskeleton which is involved in many cellular processes such as vesicular transport. The photoreceptor cells in…”
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A valid method of laparoscopic simulation training and competence assessment by ADRALES, Gina L, PARK, Adrian E, CHU, Uyen B, WITZKE, Donald B, DONNELLY, Michael B, HOSKINS, James D, MASTRANGELO, Michael J, GANDSAS, Alejandro

“…The purpose of our study was to evaluate the construct validity of laparoscopic technical performance measures and the face validity of three laparoscopic…”
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TRICHOSPORON COLONIZATION IN PATIENTS WITH CYSTIC FIBROSIS: TO TREAT OR NOT TO TREAT? THAT IS THE CLINICAL QUESTION by RAMBIE, AIMEE, SAINATO, REBECCA, COLBURN, ZACHARY, B CABOOT, JASON, HICKEY, PATRICK, JS SAKAI, JOSHUA, B CHU, UYEN

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Minimally invasive parathyroidectomy and parathyroid imaging by Chu, Uyen B., Mastrangelo, Michael J.

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Laparoscopic incisional hernia repair: a technical advance by Chu, Uyen B, Adrales, Gina L, Schwartz, Richard W, Park, Adrian E

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Photoaffinity labeling of the Sigma-1 Receptor with N-(3-(4-nitrophenyl)propyl)-N-dodecylamine (4-NPPC12) – Evidence for Receptor Dimers by Chu, Uyen B., Ramachandran, Subramaniam, Hajipour, Abdol R., Ruoho, Arnold E.

“…The sigma-1 receptor is a ligand-regulated ER resident chaperone involved in the maintenance of cellular homeostasis. Coupling of the sigma-1 receptor with…”
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