Search Results - "Chu, T."
-
1
Mechanisms of selective autophagy and mitophagy: Implications for neurodegenerative diseases
Published in Neurobiology of disease (01-02-2019)“…Over the past 20 years, the concept of mammalian autophagy as a nonselective degradation system has been repudiated, due in part to important discoveries in…”
Get full text
Journal Article -
2
The mitochondrial transcription factor TFAM in neurodegeneration: emerging evidence and mechanisms
Published in FEBS letters (01-03-2018)“…The mitochondrial transcription factor A, or TFAM, is a mitochondrial DNA (mtDNA)‐binding protein essential for genome maintenance. TFAM functions in…”
Get full text
Journal Article -
3
11 TOPS photonic convolutional accelerator for optical neural networks
Published in Nature (London) (07-01-2021)“…Convolutional neural networks, inspired by biological visual cortex systems, are a powerful category of artificial neural networks that can extract the…”
Get full text
Journal Article -
4
Excitotoxicity, calcium and mitochondria: a triad in synaptic neurodegeneration
Published in Translational neurodegeneration (25-01-2022)“…Glutamate is the most commonly engaged neurotransmitter in the mammalian central nervous system, acting to mediate excitatory neurotransmission. However, high…”
Get full text
Journal Article -
5
Metagenomics Reveals the Impact of Wastewater Treatment Plants on the Dispersal of Microorganisms and Genes in Aquatic Sediments
Published in Applied and environmental microbiology (01-03-2018)“…Wastewater treatment plants (WWTPs) release treated effluent containing mobile genetic elements (MGEs), antibiotic resistance genes (ARGs), and microorganisms…”
Get full text
Journal Article -
6
Sweet Control: MicroRNA Regulation of the Glycome
Published in Biochemistry (Easton) (01-09-2020)“…Glycosylation is a sophisticated informational system that controls specific biological functions at the cellular and organismal level. Dysregulation of…”
Get full text
Journal Article -
7
Ultra-dense optical data transmission over standard fibre with a single chip source
Published in Nature communications (22-05-2020)“…Micro-combs - optical frequency combs generated by integrated micro-cavity resonators – offer the full potential of their bulk counterparts, but in an…”
Get full text
Journal Article -
8
Generation of multiphoton entangled quantum states by means of integrated frequency combs
Published in Science (American Association for the Advancement of Science) (11-03-2016)“…Complex optical photon states with entanglement shared among several modes are critical to improving our fundamental understanding of quantum mechanics and…”
Get full text
Journal Article -
9
The establishment of the plasma cell survival niche in the bone marrow
Published in Immunological reviews (01-01-2013)“…Summary Antibodies continuously secreted by plasma cells play a central role in humoral immune protection of the organism. These plasma cells are generated…”
Get full text
Journal Article -
10
Advanced RF and microwave functions based on an integrated optical frequency comb source
Published in Optics express (05-02-2018)“…We demonstrate advanced transversal radio frequency (RF) and microwave functions based on a Kerr optical comb source generated by an integrated micro-ring…”
Get full text
Journal Article -
11
Carbon ion radiotherapy in Japan: an assessment of 20 years of clinical experience
Published in The lancet oncology (01-02-2015)“…Summary Charged particle therapy is generally regarded as cutting-edge technology in oncology. Many proton therapy centres are active in the USA, Europe, and…”
Get full text
Journal Article -
12
A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease
Published in Human molecular genetics (15-04-2010)“…The PTEN-induced putative kinase 1 (PINK1) is a mitochondrially targeted serine–threonine kinase, which is linked to autosomal recessive familial parkinsonism…”
Get full text
Journal Article -
13
Repression of miR-126 and upregulation of adrenomedullin in the stromal endothelium by cancer-stromal cross talks confers angiogenesis of cervical cancer
Published in Oncogene (10-07-2014)“…miR-126 is an endothelial-specific microRNA essential for maintaining vessel integrity during development. Its role of tumor angiogenesis in cancer stroma is…”
Get full text
Journal Article -
14
Do colorectal cancer patients diagnosed as an emergency differ from non-emergency patients in their consultation patterns and symptoms? A longitudinal data-linkage study in England
Published in British journal of cancer (27-09-2016)“…Background: More than 20% of colorectal cancers are diagnosed following an emergency presentation. We aimed to examine pre-diagnostic primary-care…”
Get full text
Journal Article -
15
Integrated frequency comb source based Hilbert transformer for wideband microwave photonic phase analysis
Published in Optics express (24-08-2015)“…We demonstrate a photonic RF Hilbert transformer for broadband microwave in-phase and quadrature-phase generation based on an integrated frequency optical…”
Get full text
Journal Article -
16
Practical system for the generation of pulsed quantum frequency combs
Published in Optics express (07-08-2017)“…The on-chip generation of large and complex optical quantum states will enable low-cost and accessible advances for quantum technologies, such as secure…”
Get full text
Journal Article -
17
Single-cell evaluation of red blood cell bio-mechanical and nano-structural alterations upon chemically induced oxidative stress
Published in Scientific reports (07-05-2015)“…Erythroid cells, specifically red blood cells (RBCs), are constantly exposed to highly reactive radicals during cellular gaseous exchange. Such exposure often…”
Get full text
Journal Article -
18
Kinesiology of Tai Chi Martial Arts – A Scientific Overview
Published in Ido movement for culture : journal of martial arts anthropology (01-01-2024)“…Background. Tai Chi Chuan (TCC) is a stand-up internal martial art, which can handle incoming forces with minimal effort and can overcome hardness with…”
Get full text
Journal Article -
19
Outcomes and intentions in children’s, adolescents’, and adults’ second- and third-party punishment behavior
Published in Cognition (01-10-2014)“…Theories of morality maintain that punishment supports the emergence and maintenance of moral behavior. This study investigated developmental differences in…”
Get full text
Journal Article -
20
Mechanical and in vivo performance of hydroxyapatite implants with controlled architectures
Published in Biomaterials (01-03-2002)“…Internal architecture has a direct impact on the mechanical and biological behaviors of porous hydroxyapatite (HA) implant. However, traditional processing…”
Get full text
Journal Article