Search Results - "Chu, Qiaoyun"

Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia by Wang, Yuanyuan, Bai, Changsen, Ruan, Yuxia, Liu, Miao, Chu, Qiaoyun, Qiu, Li, Yang, Chuanzhen, Li, Binghui

“…Under hypoxia, most of glucose is converted to secretory lactate, which leads to the overuse of glutamine-carbon. However, under such a condition how glutamine…”
Get full text

Identification of purine biosynthesis as an NADH-sensing pathway to mediate energy stress by Yang, Ronghui, Yang, Chuanzhen, Ma, Lingdi, Zhao, Yiliang, Guo, Zihao, Niu, Jing, Chu, Qiaoyun, Ma, Yingmin, Li, Binghui

“…An enhanced NADH/NAD + ratio, termed reductive stress, is associated with many diseases. However, whether a downstream sensing pathway exists to mediate…”
Get full text

Hypoxia-induced downregulation of PGK1 crotonylation promotes tumorigenesis by coordinating glycolysis and the TCA cycle by Guo, Zihao, Zhang, Yang, Wang, Haoyue, Liao, Liming, Ma, Lingdi, Zhao, Yiliang, Yang, Ronghui, Li, Xuexue, Niu, Jing, Chu, Qiaoyun, Fu, Yanxia, Li, Binghui, Yang, Chuanzhen

“…Protein post-translational modifications (PTMs) are crucial for cancer cells to adapt to hypoxia; however, the functional significance of lysine crotonylation…”
Get full text

SY-707, an ALK/FAK/IGF1R inhibitor, suppresses growth and metastasis of breast cancer cells by Liu, Ping, Sun, Yinghui, Liu, Shuang, Niu, Jing, Liu, Xijie, Chu, Qiaoyun

“…Focal adhesion kinase (FAK), a multi-functional cytoplasmic tyrosine kinase, plays a critical role in cancer migration, proliferation and metastasis via…”
Get full text

TMEM92 acts as an immune-resistance and prognostic marker in pancreatic cancer from the perspective of predictive, preventive, and personalized medicine by Zhang, Simeng, Wan, Xing, Lv, Mengzhu, Li, Ce, Chu, Qiaoyun, Wang, Guan

“…Background Pancreatic cancer presents extremely poor prognosis due to the difficulty of early diagnosis, low resection rate, and high rates of recurrence and…”
Get full text

CDK5 positively regulates Notch1 signaling in pancreatic cancer cells by phosphorylation by Chu, Qiaoyun, Wang, Liyong, Zhang, Jie, Wang, Wei, Wang, Youxin

“…The marked overexpression of cyclin‐dependent kinase 5 (CDK5) or Notch1 receptor, which plays critical roles in pancreatic ductal adenocarcinoma (PDAC)…”
Get full text

Periodic Changes in the N-Glycosylation of Immunoglobulin G During the Menstrual Cycle by Jurić, Julija, Peng, Hongli, Song, Manshu, Vučković, Frano, Šimunović, Jelena, Trbojević-Akmačić, Irena, Wang, Youxin, Liu, Jiaonan, Gao, Qing, Wang, Hao, Chu, Qiaoyun, Pezer, Marija, Wang, Wei, Lauc, Gordan

“…Immunoglobulin G (IgG) is the most abundant plasma glycoprotein and a prominent humoral immune mediator. Glycan composition affects the affinity of IgG to…”
Get full text

Association between dopaminergic genes ( and ) and stuttering among Han Chinese by Lan, Jie, Song, Manshu, Pan, Chunhui, Zhuang, Guoqing, Wang, Youxin, Ma, Wenzhan, Chu, Qiaoyun, Lai, Qingxuan, Xu, Feng, Li, Yanli, Liu, Lixin, Wang, Wei

“…Normal function of the dopaminergic system is necessary for speech fluency. There was evidence that the activities of dopamine transporter (DAT) and dopamine…”
Get full text

hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation by Xing, Yingying, Chu, Qiaoyun, Feng, Run, Wang, Wei, Liu, Lixin, Lu, Zhongbing

“…hCLP46 （human CAP10-1ike protein 46 kDa） was initially isolated and identified from human acute myeloid leukemia transformed from myelodysplastic syndrome…”
Get full text

Erratum to： hCLP46 increases Smad3 protein stability via inhibiting its ubiquitin-proteasomal degradation by Xing, Yingying, Chu, Qiaoyun, Feng, Run, Wang, Wei, Liu, Lixin, Lu, Zhongbing

“…In the original publication of the article, co-authors affiliations are appeared incorrectly. Correct affiliations are provided in this erratum…”
Get full text

De novo pyrimidine biosynthetic complexes support cancer cell proliferation and ferroptosis defence by Yang, Chuanzhen, Zhao, Yiliang, Wang, Liao, Guo, Zihao, Ma, Lingdi, Yang, Ronghui, Wu, Ying, Li, Xuexue, Niu, Jing, Chu, Qiaoyun, Fu, Yanxia, Li, Binghui

“…De novo pyrimidine biosynthesis is achieved by cytosolic carbamoyl-phosphate synthetase II, aspartate transcarbamylase and dihydroorotase (CAD) and uridine…”
Get full text

Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth by Liu, Miao, Wang, Yuanyuan, Yang, Chuanzhen, Ruan, Yuxia, Bai, Changsen, Chu, Qiaoyun, Cui, Yanfen, Chen, Ceshi, Ying, Guoguang, Li, Binghui

“…Cancer cells often proliferate under hypoxia and reprogram their metabolism. However, how to find targets to effectively block the hypoxia-associated metabolic…”
Get full text

Repurposing a tricyclic antidepressant in tumor and metabolism disease treatment through fatty acid uptake inhibition by Chu, Qiaoyun, An, Jing, Liu, Ping, Song, Yihan, Zhai, Xuewei, Yang, Ronghui, Niu, Jing, Yang, Chuanzhen, Li, Binghui

“…Fatty acid uptake is essential for cell physiological function, but detailed mechanisms remain unclear. Here, we generated an acetyl-CoA carboxylases (ACC1/2)…”
Get full text

Stearate‐derived very long‐chain fatty acids are indispensable to tumor growth by Chu, Qiaoyun, Liu, Ping, Song, Yihan, Yang, Ronghui, An, Jing, Zhai, Xuewei, Niu, Jing, Yang, Chuanzhen, Li, Binghui

“…Reprogramming of lipid metabolism is emerging as a hallmark of cancer, yet involvement of specific fatty acids (FA) species and related enzymes in…”
Get full text

Stearate‐derived very long‐chain fatty acids are indispensable to tumor growth by Chu, Qiaoyun, Liu, Ping, Song, Yihan, Yang, Ronghui, An, Jing, Zhai, Xuewei, Niu, Jing, Yang, Chuanzhen, Li, Binghui

Get full text

Erratum To: Stearate‐derived very long‐chain fatty acids are indispensable to tumor growth by Chu, Qiaoyun, Liu, Ping, Song, Yihan, Yang, Ronghui, An, Jing, Zhai, Xuewei, Niu, Jing, Yang, Chuanzhen, Li, Binghui

“…Graphical Abstract…”
Get full text

hCLP46 regulates U937 cell proliferation via Notch signaling pathway by Ma, Wenzhan, Du, Jie, Chu, Qiaoyun, Wang, Youxin, Liu, Lixin, Song, Manshu, Wang, Wei

“…► Knock down of hCLP46 by RNAi impairs mammalian Notch signaling. ► hCLP46 affects neither cell surface Notch1 expression nor ligand–receptor binding. ► Knock…”
Get full text

Human CAP10-Like Protein 46 kDa Gene Promotes Malignancy in Colorectal Cancer by Fang, Honghong, Chu, Qiaoyun, Zhang, Jie, Wang, Hao, Yu, Xinwei, Ge, Siqi, Song, Manshu, Wu, Lijuan, Lang, Minglin, Chang, Naibai, Wang, Youxin, Wang, Wei

“…Colon cancer patients have major unmet needs in terms of robust diagnostics and molecular biomarkers for personalized therapeutics. We have previously reported…”
Get more information

Overexpression of human CAP10-like protein 46 KD in T-acute lymphoblastic leukemia and acute myelogenous leukemia by Wang, Youxin, Chang, Naibai, Zhang, Tian, Liu, Hui, Ma, Wenzhan, Chu, Qiaoyun, Lai, Qingxuan, Liu, Lixin, Wang, Wei

“…We earlier identified a novel gene human CAP10-like protein 46 KD (hCLP46) from human acute myelogenous leukemia (AML) transformed from myelodysplastic…”
Get more information