Search Results - "Chu, Mingxing"
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Photoperiod Induces the Epigenetic Change of the GNAQ Gene in OVX+E2 Ewes
Published in International journal of molecular sciences (01-11-2023)“…GNAQ, a member of the alpha subunit encoding the q-like G protein, is a critical gene in cell signaling, and multiple studies have shown that upregulation of…”
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2
Lin28 gene and mammalian puberty
Published in Molecular reproduction and development (01-05-2020)“…Lin28a and Lin28b, homologs of the Caenorhabditis elegans Lin28 gene, play important roles in cell pluripotency, reprogramming, and tumorigenicity. Recently,…”
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3
Key mRNAs and lncRNAs of pituitary that affect the reproduction of FecB + + small tail han sheep
Published in BMC genomics (22-04-2024)“…The pituitary directly regulates the reproductive process through follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Transcriptomic research on…”
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Photoperiod Induces DNA Methylation Changes in the Melatonin Receptor 1A Gene in Ewes
Published in Animals (Basel) (01-06-2023)“…Research has shown that MTNR1A plays an essential role in the estrus cycle and seasonal reproduction changes in sheep. However, few people have focused on the…”
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Integrated analyses of miRNA-mRNA expression profiles of ovaries reveal the crucial interaction networks that regulate the prolificacy of goats in the follicular phase
Published in BMC genomics (11-11-2021)“…Abstract Background Litter size is an important index of mammalian prolificacy and is determined by the ovulation rate. The ovary is a crucial organ for…”
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6
Transcriptome study digs out BMP2 involved in adipogenesis in sheep tails
Published in BMC genomics (21-06-2022)“…Abstract Background Hu sheep and Tibetan sheep in China are characterized by fat tails and thin tails, respectively. Several transcriptomes have been conducted…”
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Differentially Expressed Circular RNA Profile Signatures Identified in Prolificacy Trait of Yunshang Black Goat Ovary at Estrus Cycle
Published in Frontiers in physiology (04-04-2022)“…CircRNAs acting as miRNA sponges play important roles in the growth process of animal individuals. The prolificacy trait of goats is involved in many pathways,…”
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Trend analysis of the role of circular RNA in goat skeletal muscle development
Published in BMC genomics (10-03-2020)“…Circular RNA (circRNA) is produced during the splicing of mRNA (in addition to linear splicing) and is part of the gene regulatory network. The temporal…”
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Integration analysis of pituitary proteome and transcriptome reveals fertility-related biomarkers in FecB mutant Small Tail Han sheep
Published in Frontiers in endocrinology (Lausanne) (23-07-2024)“…The Booroola fecundity mutation (FecB) in Small Tail Han sheep has been shown to enhance ovulation rates and litter sizes by affecting the…”
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10
Photoperiods induced the circRNA differential expression in the thyroid gland of OVX+E2 ewes
Published in Frontiers in endocrinology (Lausanne) (29-08-2022)“…Circular RNAs (circRNAs) are non-coding RNAs newly identified and play important roles in RNA regulation. However, little is known regarding photoperiods…”
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miRNA-mRNA analysis of sheep adrenal glands reveals the network regulating reproduction
Published in BMC genetics (17-06-2022)“…Abstract Background The adrenal gland participates in the process of sheep reproduction. MicroRNAs (miRNAs), endogenous small noncoding RNAs, regulate gene…”
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12
Genetic diversity, tissue-specific expression, and functional analysis of the ATP7A gene in sheep
Published in Frontiers in genetics (20-09-2023)“…In humans, variation of the gene may cause cranial exostosis, which is similar to "human horn," but the function of the gene in sheep is still unknown. Tissue…”
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13
Integrative Proteomics and Transcriptomics Profiles of the Oviduct Reveal the Prolificacy-Related Candidate Biomarkers of Goats ( Capra hircus ) in Estrous Periods
Published in International journal of molecular sciences (28-11-2022)“…The oviduct is a dynamic reproductive organ for mammalian reproduction and is required for gamete storage, maturation, fertilization, and early embryonic…”
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14
Single-cell RNA-seq reveals the effects of the FecB mutation on the transcriptome profile in ovine cumulus cells
Published in Scientific reports (07-06-2024)“…Genetic variations in the ovine ovulation rate, which are associated with the FecB mutation, provide useful models by which to explore the mechanisms…”
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15
Rapid evolution of a retro-transposable hotspot of ovine genome underlies the alteration of BMP2 expression and development of fat tails
Published in BMC genomics (02-04-2019)“…Sheep have developed the ability to store fat in their tails, which is a unique way of reserving energy to survive a harsh environment. However, the mechanism…”
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Comprehensive Analysis of LncRNA Reveals the Temporal-Specific Module of Goat Skeletal Muscle Development
Published in International journal of molecular sciences (14-08-2019)“…A series of complex processes regulate muscle development, and lncRNAs play essential roles in the regulation of skeletal myogenesis. Using RNA sequencing, we…”
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Uterus proliferative period ceRNA network of Yunshang black goat reveals candidate genes on different kidding number trait
Published in Frontiers in endocrinology (Lausanne) (12-05-2023)“…Pregnancy loss that occurs in the uterus is an important and widespread problem in humans and farm animals and is also a key factor affecting the fecundity of…”
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18
Litter Size of Sheep ( Ovis aries ): Inbreeding Depression and Homozygous Regions
Published in Genes (18-01-2021)“…Ovine litter size (LS) is an important trait showing variability within breeds. It remains largely unknown whether inbreeding depression on LS exists based on…”
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Screening of Litter-Size-Associated SNPs in NOX4, PDE11A and GHR Genes of Sheep
Published in Animals (Basel) (29-02-2024)“…In previous studies, , and genes have been screened as important candidate genes for litter size in sheep by using the GWAS method; however, neither their…”
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20
Metabolic Effects of FecB Gene on Follicular Fluid and Ovarian Vein Serum in Sheep (Ovis aries)
Published in International journal of molecular sciences (11-02-2018)“…The gene has been discovered as an important gene in sheep for its high relationship with the ovulation rate, but its regulatory mechanism remains unknown. In…”
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