Search Results - "Chu, Michelle L"
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The role of PDF neurons in setting the preferred temperature before dawn in Drosophila
Published in eLife (02-05-2017)“…Animals have sophisticated homeostatic controls. While mammalian body temperature fluctuates throughout the day, small ectotherms, such as achieve a body…”
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Directed evolution reveals the mechanism of HitRS signaling transduction in Bacillus anthracis
Published in PLoS pathogens (23-12-2020)“…Two component systems (TCSs) are a primary mechanism of signal sensing and response in bacteria. Systematic characterization of an entire TCS could provide a…”
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Drosophila DH31 Neuropeptide and PDF Receptor Regulate Night-Onset Temperature Preference
Published in The Journal of neuroscience (16-11-2016)“…Body temperature exhibits rhythmic fluctuations over a 24 h period (Refinetti and Menaker, 1992) and decreases during the night, which is associated with sleep…”
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Feeding-State-Dependent Modulation of Temperature Preference Requires Insulin Signaling in Drosophila Warm-Sensing Neurons
Published in Current biology (05-03-2018)“…Starvation is life-threatening and therefore strongly modulates many aspects of animal behavior and physiology [1]. In mammals, hunger causes a reduction in…”
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Calcitonin receptors are ancient modulators for rhythms of preferential temperature in insects and body temperature in mammals
Published in Genes & development (15-01-2018)“…Daily body temperature rhythm (BTR) is essential for maintaining homeostasis. BTR is regulated separately from locomotor activity rhythms, but its molecular…”
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DnaJ and ClpX Are Required for HitRS and HssRS Two-Component System Signaling in Bacillus anthracis
Published in Infection and immunity (25-01-2022)“…Bacillus anthracis is the causative agent of anthrax. This Gram-positive bacterium poses a substantial risk to human health due to high mortality rates and the…”
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Heme sensing in Bacillus thuringiensis: a supplementary HssRS-regulated heme resistance system
Published in FEMS microbiology letters (01-05-2016)“…Several Gram-positive pathogens scavenge host-derived heme to satisfy their nutritional iron requirement. However, heme is a toxic molecule capable of damaging…”
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