Search Results - "Chu, Liangzhao"

Overexpression of CD2/CD27 could inhibit the activation of nitrogen metabolism pathways and suppress M2 polarization of macrophages, thereby preventing brain metastasis of breast cancer by Huang, Guanyou, Wu, Yujuan, Gan, Hongchuan, Chu, Liangzhao

“…•CD2 and CD27 are the core immune genes involved in brain metastases of BC.•CD2 and CD27 expression are closely associated with brain metastases of BC.•Reduced…”
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Mitochondrial RNA modification-based signature to predict prognosis of lower grade glioma: a multi-omics exploration and verification study by Zhou, Xingwang, Ling, Yuanguo, Cui, Junshuan, Wang, Xiang, Long, Niya, Teng, Wei, Liu, Jian, Xiang, Xin, Yang, Hua, Chu, Liangzhao

“…Mitochondrial RNA modification (MRM) plays a crucial role in regulating the expression of key mitochondrial genes and promoting tumor metastasis. Despite its…”
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USP10 deubiquitinates RUNX1 and promotes proneural-to-mesenchymal transition in glioblastoma by Qiu, Wenjin, Xiao, Zumu, Yang, Yushi, Jiang, Lishi, Song, Shibin, Qi, Xiaolan, Chen, Yimin, Yang, Hua, Liu, Jian, Chu, Liangzhao

“…The mesenchymal (MES) subtype of glioblastoma (GBM) is a highly aggressive, malignant and proliferative cancer that is resistant to chemotherapy. Runt-related…”
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Therapeutic effects of orexin-A in sepsis-associated encephalopathy in mice by Guo, Jing, Kong, Zhuo, Yang, Sha, Da, Jingjing, Chu, Liangzhao, Han, Guoqiang, Liu, Jian, Tan, Ying, Zhang, Jiqin

“…Sepsis-associated encephalopathy (SAE) causes acute and long-term cognitive deficits. However, information on the prevention and treatment of cognitive…”
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The role of tumor-associated macrophages in glioma cohort: through both traditional RNA sequencing and single cell RNA sequencing by Hou, Yunan, Qiu, Wenjin, Ling, Yuanguo, Qi, Xiaolan, Liu, Jian, Yang, Hua, Chu, Liangzhao

“…Gliomas are the leading cause in more than 50% of malignant brain tumor cases. Prognoses, recurrences, and mortality are usually poor for gliomas that have…”
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CircPOSTN/miR-361-5p/TPX2 axis regulates cell growth, apoptosis and aerobic glycolysis in glioma cells by Long, Niya, Chu, Liangzhao, Jia, Jun, Peng, Shuo, Gao, Yuan, Yang, Hua, Yang, Yaoming, Zhao, Yan, Liu, Jian

“…Glioma is the most primary central nervous system tumor in adults. The 5 year survival rate for glioma patients remains poor, although treatment strategies had…”
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TPPP3 promote epithelial-mesenchymal transition via Snail1 in glioblastoma by Xu, Xu, Hou, Yunan, Long, Niya, Jiang, Lishi, Yan, Zhangwei, Xu, Yuan, Lv, Ying, Xiang, Xin, Yang, Hua, Liu, Jian, Qi, Xiaolan, Chu, Liangzhao

“…Tubulin polymerization promoting protein 3 (TPPP3), a member of the tubulin polymerization family, participates in cell progressions in several human cancers,…”
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Knockdown of CREB3 activates endoplasmic reticulum stress and induces apoptosis in glioblastoma by Hu, Yaxin, Chu, Liangzhao, Liu, Jian, Yu, Lei, Song, Shi-Bin, Yang, Hua, Han, Feng

“…Glioblastoma is a highly malignant type of central nervous system tumor. In the present study, the results of RNA sequencing indicated that cAMP responsive…”
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PRL1 Promotes Glioblastoma Invasion and Tumorigenesis via Activating USP36-Mediated Snail2 Deubiquitination by Qiu, Wenjin, Cai, Xiaomin, Xu, Kaya, Song, Shibin, Xiao, Zumu, Hou, Yunan, Qi, Xiaolan, Liu, Feng, Chen, Yimin, Yang, Hua, Chu, Liangzhao, Liu, Jian

“…Regenerating liver phosphatase 1 (PRL1) is an established oncogene in various cancers, although its biological function and the underlying mechanisms in…”
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Machine learning unveils immune-related signature in multicenter glioma studies by Yang, Sha, Wang, Xiang, Huan, Renzheng, Deng, Mei, Kong, Zhuo, Xiong, Yunbiao, Luo, Tao, Jin, Zheng, Liu, Jian, Chu, Liangzhao, Han, Guoqiang, Zhang, Jiqin, Tan, Ying

“…In glioma molecular subtyping, existing biomarkers are limited, prompting the development of new ones. We present a multicenter study-derived consensus…”
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Circular RNA circPOSTN promotes neovascularization by regulating miR-219a-2-3p/STC1 axis and stimulating the secretion of VEGFA in glioblastoma by Long, Niya, Xu, Xu, Lin, Hongyi, Lv, Ying, Zou, Shenghui, Cao, Han, Chen, Xueshu, Zhao, Yan, Qi, Xiaolan, Yang, Hua, Liu, Jian, Chu, Liangzhao

“…Glioblastoma (GBM), the most malignant type of astrocytic tumor, is one of the deadliest cancers prevalent in adults. Along with tumor growth, patients with…”
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Causal role of peripheral immune cells in epilepsy: A large-scale genetic correlation study by Zhao, Ting, Cui, Junshuan, Lan, Shengjiao, Chu, Liangzhao, Tian, Shufen, Zhou, Xingwang

“…•The Maturation stages of T cell serve as a protective factor for epilepsy and generalized epilepsy.•Myeloid cell is specifically protective for generalized…”
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Long noncoding RNA SNHG12 facilitates the tumorigenesis of glioma through miR-101-3p/FOXP1 axis by Sun, Yuchen, Liu, Jian, Chu, Liangzhao, Yang, Wenxiu, Liu, Hongjiang, Li, Chen, Yang, Jipeng

“…The increasing vital roles of long coding RNA (lncRNAs) in the glioma tumorigenesis have renewedly and roundly recognized. Nevertheless, the in-depth that…”
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Radiosurgical Biologically Effective Dose on Trigeminal Root Division and Section for Outcomes of Idiopathic Trigeminal Neuralgia Type 1: A Multicentre Retrospective Cohort Study by Tang, Ke, Zhang, Nan, Yuan, Xiaodong, Chu, Liangzhao, Qian, Zenghui, Li, Yang

“…The wide variability in the efficacy of Gamma Knife surgery (GKS) treating trigeminal neuralgia type 1 (TN1) has not been completely elucidated. We aimed to…”
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Effects of Gastrodin on BV2 cells under oxygen-glucose deprivation and its mechanism by Lv, Ying, Cao, Han, Chu, Liangzhao, Peng, Han, Shen, Xiangchun, Yang, Hua

“…•Microglia play key role in the occurrence, development and outcome of ischemic cerebrovascular disease.•Gastrodin has a dual effect on microglia with…”
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EphB3 receptor suppressor invasion, migration and proliferation in glioma by inhibiting EGFR-PI3K/AKT signaling pathway by Xiao, Zumu, Huang, Shengxuan, Qiu, Wenjin, Pang, Mengru, Zeng, Xi, Xu, Xu, Yang, Yushi, Yang, Binglin, Chu, Liangzhao

“…[Display omitted] •EphB3 receptor is downregulated in glioma tissues and cell lines with increasing tumor grade.•Knockdown of EphB3 gene enhances invasion,…”
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Whole-Exome Sequencing Reveals Novel Variations in Patients with Familial Von Hippel−Lindau Syndrome by Zhou, Yuhao, Liu, Jian, Chu, Liangzhao, Dong, Minghao, Feng, Luqian

“…Von Hippel−Lindau (VHL) syndrome is a rare disease that occurs in an autosomal-dominant genetic pattern. Due to the high genetic variability of VHL diseases,…”
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Repurposing flubendazole for glioblastoma ferroptosis by affecting xCT and TFRC proteins by Teng, Wei, Ling, Yuanguo, Long, Niya, Cen, Wu, Zhang, Hongzhi, Jiang, Lishi, Liu, Jian, Zhou, Xingwang, Chu, Liangzhao

“…Abstract New uses of old drugs hold great promise for clinical translation. Flubendazole, an FDA‐approved antiparasitic drug, has been shown to target p53 and…”
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Curcumin-polydopamine nanoparticles alleviate ferroptosis by iron chelation and inhibition of oxidative stress damage by Lei, Li, Yuan, Jiali, Yang, Qingqing, Tu, Qiuxia, Yu, Haijun, Chu, Liangzhao, Tang, Lei, Zhang, Chunlin

“…Ferroptosis, characterized by elevated iron levels and lipid peroxidation (LPO), is a recently identified regulatory mechanism of cell death. Its substantial…”
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MicroRNA‑451 relieves inflammation in cerebral ischemia‑reperfusion via the Toll‑like receptor 4/MyD88/NF‑κB signaling pathway by Li, Wenyan, Dong, Minghao, Chu, Liangzhao, Feng, Luqian, Sun, Xiaochuan

“…The present study was designed to investigate the role of microRNA‑451 (miRNA‑451) on cerebral ischemia‑reperfusion and to explore its possible mechanism. The…”
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