Search Results - "Chu, Jeffrey S C"

GenBlastA: enabling BLAST to identify homologous gene sequences by She, Rong, Chu, Jeffrey S-C, Wang, Ke, Pei, Jian, Chen, Nansheng

“…BLAST is an extensively used local similarity search tool for identifying homologous sequences. When a gene sequence (either protein sequence or nucleotide…”
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Mutational landscape of intrahepatic cholangiocarcinoma by Zou, Shanshan, Li, Jiarui, Zhou, Huabang, Frech, Christian, Jiang, Xiaolan, Chu, Jeffrey S. C., Zhao, Xinyin, Li, Yuqiong, Li, Qiaomei, Wang, Hui, Hu, Jingyi, Kong, Guanyi, Wu, Mengchao, Ding, Chuanfan, Chen, Nansheng, Hu, Heping

“…Intrahepatic cholangiocarcinoma (ICC) is a fatal primary liver cancer (PLC) that affects 5–10% of all PLCs. Here we sequence tumour and matching control sample…”
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Single-molecule real-time transcript sequencing facilitates common wheat genome annotation and grain transcriptome research by Dong, Lingli, Liu, Hongfang, Zhang, Juncheng, Yang, Shuangjuan, Kong, Guanyi, Chu, Jeffrey S C, Chen, Nansheng, Wang, Daowen

“…The large and complex hexaploid genome has greatly hindered genomics studies of common wheat (Triticum aestivum, AABBDD). Here, we investigated transcripts in…”
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Genomics insights into different cellobiose hydrolysis activities in two Trichoderma hamatum strains by Cheng, Peng, Liu, Bo, Su, Yi, Hu, Yao, Hong, Yahui, Yi, Xinxin, Chen, Lei, Su, Shengying, Chu, Jeffrey S C, Chen, Nansheng, Xiong, Xingyao

“…Efficient biomass bioconversion is a promising solution to alternative energy resources and environmental issues associated with lignocellulosic wastes. The…”
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Genome-wide variations in a natural isolate of the nematode Caenorhabditis elegans by Vergara, Ismael A, Tarailo-Graovac, Maja, Frech, Christian, Wang, Jun, Qin, Zhaozhao, Zhang, Ting, She, Rong, Chu, Jeffrey S C, Wang, Ke, Chen, Nansheng

“…Increasing genetic and phenotypic differences found among natural isolates of C. elegans have encouraged researchers to explore the natural variation of this…”
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Convergent evolution of RFX transcription factors and ciliary genes predated the origin of metazoans by Chu, Jeffrey S C, Baillie, David L, Chen, Nansheng

“…Intraflagellar transport (IFT) genes, which are critical for the development and function of cilia and flagella in metazoans, are tightly regulated by the…”
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Allelic ratios and the mutational landscape reveal biologically significant heterozygous SNVs by Chu, Jeffrey S-C, Johnsen, Robert C, Chua, Shu Yi, Tu, Domena, Dennison, Mark, Marra, Marco, Jones, Steven J M, Baillie, David L, Rose, Ann M

“…The issue of heterozygosity continues to be a challenge in the analysis of genome sequences. In this article, we describe the use of allele ratios to…”
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RNA-seq analysis of the C. briggsae transcriptome by Uyar, Bora, Chu, Jeffrey S C, Vergara, Ismael A, Chua, Shu Yi, Jones, Martin R, Wong, Tammy, Baillie, David L, Chen, Nansheng

“…Curation of a high-quality gene set is the critical first step in genome research, enabling subsequent analyses such as ortholog assignment, cis-regulatory…”
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Genome-Wide Mutational Signature of the Chemotherapeutic Agent Mitomycin C in Caenorhabditis elegans by Tam, Annie S, Chu, Jeffrey S C, Rose, Ann M

“…Cancer therapy largely depends on chemotherapeutic agents that generate DNA lesions. However, our understanding of the nature of the resulting lesions as well…”
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Spindle assembly checkpoint genes reveal distinct as well as overlapping expression that implicates MDF-2/Mad2 in postembryonic seam cell proliferation in Caenorhabditis elegans by Tarailo-Graovac, Maja, Wang, Jun, Chu, Jeffrey S C, Tu, Domena, Baillie, David L, Chen, Nansheng

“…The spindle assembly checkpoint (SAC) delays anaphase onset by inhibiting the activity of the anaphase promoting complex/cyclosome (APC/C) until all of the…”
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