Search Results - "Chu, In‐Sun"

Activation of EZH2 and SUZ12 Regulated by E2F1 Predicts the Disease Progression and Aggressive Characteristics of Bladder Cancer by Lee, Se-Ra, Roh, Yun-Gil, Kim, Seon-Kyu, Lee, Ju-Seog, Seol, So-Young, Lee, Hyun-Hee, Kim, Won-Tae, Kim, Wun-Jae, Heo, Jeonghoon, Cha, Hee-Jae, Kang, Tae-Hong, Chung, Jin Woong, Chu, In-Sun, Leem, Sun-Hee

“…Previous study identified E2F1 as a key mediator of non-muscle-invasive bladder cancer (NMIBC) progression. The aim of this study was to identify the…”
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Gene Expression Signature-Based Prognostic Risk Score in Gastric Cancer by JAE YONG CHO, JAE YUN LIM, SUNG HOON NOH, EUN SUNG PARK, CHU, In-Sun, WAUN KI HONG, AJANI, Jaffer A, LEE, Ju-Seog, JAE HO CHEONG, PARK, Yun-Yong, YOON, Se-Lyun, SOO MI KIM, KIM, Sang-Bae, KIM, Hoguen, SOON WON HONG, YOUNG NYUN PARK

“…Despite continual efforts to develop a prognostic model of gastric cancer by using clinical and pathologic parameters, a clinical test that can discriminate…”
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Expression Signature of E2F1 and Its Associated Genes Predict Superficial to Invasive Progression of Bladder Tumors by LEE, Ju-Seog, LEEM, Sun-Hee, LEE, Sang-Yeop, KIM, Sang-Cheol, PARK, Eun-Sung, KIM, Sang-Bae, KIM, Seon-Kyu, KIM, Yong-June, KIM, Wun-Jae, CHU, In-Sun

“…In approximately 20% of patients with superficial bladder tumors, the tumors progress to invasive tumors after treatment. Current methods of predicting the…”
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Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling by Lee, Ju‐Seog, Chu, In‐Sun, Heo, Jeonghoon, Calvisi, Diego F., Sun, Zongtang, Roskams, Tania, Durnez, Anne, Demetris, Anthony J., Thorgeirsson, Snorri S.

“…We analyzed global gene expression patterns of 91 human hepatocellular carcinomas (HCCs) to define the molecular characteristics of the tumors and to test the…”
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Lipocalin‐2 negatively modulates the epithelial‐to‐mesenchymal transition in hepatocellular carcinoma through the epidermal growth factor (TGF‐beta1)/Lcn2/Twist1 pathway by Wang, Yun‐Peng, Yu, Goung‐Ran, Lee, Mi‐Jin, Lee, Sang‐Yeop, Chu, In‐Sun, Leem, Sun‐Hee, Kim, Dae‐Ghon

“…Lipocalin‐2 (Lcn2) is preferentially expressed in hepatocellular carcinoma (HCC). However, the functional role of Lcn2 in HCC progression is still poorly…”
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Identification of an immunotherapy-responsive molecular subtype of bladder cancer by Song, Bic-Na, Kim, Seon-Kyu, Mun, Jeong-Yeon, Choi, Young-Deuk, Leem, Sun-Hee, Chu, In-Sun

“…Although various molecular subtypes of bladder cancer (BC) have been investigated, most of these studies have focused on muscle-invasive BC (MIBC). A few…”
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Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation by Cho, Hyun-Jai, Lee, Choon-Soo, Kwon, Yoo-Wook, Paek, Jae Seung, Lee, Sun-Hee, Hur, Jin, Lee, Eun Ju, Roh, Tae-Young, Chu, In-Sun, Leem, Sun-Hee, Kim, Youngsoo, Kang, Hyun-Jae, Park, Young-Bae, Kim, Hyo-Soo

“…The concept of reprogramming of somatic cells has opened a new era in regenerative medicine. Transduction of defined factors has successfully achieved…”
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A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cells by Thorgeirsson, Snorri S, Lee, Ju-Seog, Heo, Jeonghoon, Libbrecht, Louis, Chu, In-Sun, Kaposi-Novak, Pal, Calvisi, Diego F, Mikaelyan, Arsen, Roberts, Lewis R, Demetris, Anthony J, Sun, Zongtang, Nevens, Frederik, Roskams, Tania

“…The variability in the prognosis of individuals with hepatocellular carcinoma (HCC) suggests that HCC may comprise several distinct biological phenotypes…”
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E2F1 Promotes Progression of Bladder Cancer by Modulating RAD54L Involved in Homologous Recombination Repair by Mun, Jeong-Yeon, Baek, Seung-Woo, Park, Won Young, Kim, Won-Tae, Kim, Seon-Kyu, Roh, Yun-Gil, Jeong, Mi-So, Yang, Gi-Eun, Lee, Jong-Ho, Chung, Jin Woong, Choi, Yung Hyun, Chu, In-Sun, Leem, Sun-Hee

“…DNA repair defects are important factors in cancer development. High DNA repair activity can affect cancer progression and chemoresistance. DNA double-strand…”
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Histone deacetylase 6 functions as a tumor suppressor by activating c-Jun NH2-terminal kinase-mediated beclin 1-dependent autophagic cell death in liver cancer by Jung, Kwang Hwa, Noh, Ji Heon, Kim, Jeong Kyu, Eun, Jung Woo, Bae, Hyun Jin, Chang, Young Gyoon, Kim, Min Gyu, Park, Won Sang, Lee, Jung Young, Lee, Sang-Yeop, Chu, In-Sun, Nam, Suk Woo

“…Ubiquitin‐binding histone deacetylase 6 (HDAC6) is uniquely endowed with tubulin deacetylase activity and plays an important role in the clearance of misfolded…”
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Genomic predictors for recurrence patterns of hepatocellular carcinoma: model derivation and validation by Kim, Ji Hoon, Sohn, Bo Hwa, Lee, Hyun-Sung, Kim, Sang-Bae, Yoo, Jeong Eun, Park, Yun-Yong, Jeong, Woojin, Lee, Sung Sook, Park, Eun Sung, Kaseb, Ahmed, Kim, Baek Hui, Kim, Wan Bae, Yeon, Jong Eun, Byun, Kwan Soo, Chu, In-Sun, Kim, Sung Soo, Wang, Xin Wei, Thorgeirsson, Snorri S, Luk, John M, Kang, Koo Jeong, Heo, Jeonghoon, Park, Young Nyun, Lee, Ju-Seog

“…Typically observed at 2 y after surgical resection, late recurrence is a major challenge in the management of hepatocellular carcinoma (HCC). We aimed to…”
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Regulation of Cell Proliferation and Migration by Keratin19-Induced Nuclear Import of Early Growth Response-1 in Breast Cancer Cells by JU, Ji-Hyun, WONSEOK YANG, LEE, Kyung-Min, SUNHWA OH, KEESOO NAM, SHIM, Sarah, SOON YOUNG SHIN, MYUNG CHAN GYE, CHU, In-Sun, INCHEOL SHIN

“…Keratin19 (KRT19) is the smallest known type I intermediate filament and is used as a marker for reverse transcriptase PCR-mediated detection of disseminated…”
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Application of comparative functional genomics to identify best-fit mouse models to study human cancer by Thorgeirsson, Snorri S, Lee, Ju-Seog, Chu, In-Sun, Mikaelyan, Arsen, Calvisi, Diego F, Heo, Jeonghoon, Reddy, Janardan K

“…Genetically modified mice have been extensively used for analyzing the molecular events that occur during tumor development. In many, if not all, cases,…”
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Transcriptional Profiling of Advanced Urothelial Cancer Predicts Prognosis and Response to Immunotherapy by Baek, Seung-Woo, Jang, In-Hwan, Kim, Seon-Kyu, Nam, Jong-Kil, Leem, Sun-Hee, Chu, In-Sun

“…Recent investigations reported that some subtypes from the Lund or The Cancer Genome Atlas (TCGA) classifications were most responsive to PD-L1 inhibitor…”
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Fanconi Anemia Pathway Activation by FOXM1 is Critical to Bladder Cancer Recurrence and Anticancer Drug Resistance by Roh, Yun-Gil, Mun, Jeong-Yeon, Kim, Seon-Kyu, Park, Won Young, Jeong, Mi-So, Kim, Tae Nam, Kim, Won-Tae, Choi, Yung Hyun, Chu, In-Sun, Leem, Sun-Hee

“…Although the 5-year survival rate of patients diagnosed with nonmuscle invasive bladder cancer (NMIBC) has reached 85%, more than 50% of patients suffer from…”
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Sulfatase 1 and sulfatase 2 in hepatocellular carcinoma: Associated signaling pathways, tumor phenotypes, and survival by Yang, Ju Dong, Sun, Zhifu, Hu, Chunling, Lai, Jinping, Dove, Rebecca, Nakamura, Ikuo, Lee, Ju-Seog, Thorgeirsson, Snorri S., Kang, Koo Jeong, Chu, In-Sun, Roberts, Lewis R.

“…The heparin‐degrading endosulfatases sulfatase 1 (SULF1) and sulfatase 2 (SULF2) have opposing effects in hepatocarcinogenesis despite structural similarity…”
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Heterogeneous Niche Activity of Ex-Vivo Expanded MSCs as Factor for Variable Outcomes in Hematopoietic Recovery by Kim, Jung-Ho, Lee, Ho-Sun, Choi, Hyun-Kyung, Kim, Jin-A, Chu, In-Sun, Leem, Sun-Hee, Oh, Il-Hoan

“…Ex-vivo expanded mesenchymal stromal cells (MSCs) are increasingly used for paracrine support of hematopoietic stem cell (HSC) regeneration, but inconsistent…”
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Gene Expression–Based Recurrence Prediction of Hepatitis B Virus–Related Human Hepatocellular Carcinoma by HYUN GOO WOO, EUN SUNG PARK, YOON, Jung-Hwan, LEE, Hyo-Suk, CHUNG YONG KIM, YI, Nam-Joon, SUH, Kyung-Suk, KUHN UK LEE, CHU, In-Sun, ROSKAMS, Tania, THORGEIRSSON, Snorri S, YOON JUN KIM, JAE HEE CHEON, JU HAN KIM, LEE, Ju-Seog, BUM JOON PARK, KIM, Won, SU CHEOL PARK, YOUNG JIN CHUNG, BYEONG GWAN KIM

“…Purpose: The poor prognosis of hepatocellular carcinoma (HCC) is, in part, due to the high rate of recurrence even after “curative resection” of tumors…”
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Development and validation of a prognostic gene-expression signature for lung adenocarcinoma by Park, Yun-Yong, Park, Eun Sung, Kim, Sang Bae, Kim, Sang Cheol, Sohn, Bo Hwa, Chu, In-Sun, Jeong, Woojin, Mills, Gordon B, Byers, Lauren Averett, Lee, Ju-Seog

“…Although several prognostic signatures have been developed in lung cancer, their application in clinical practice has been limited because they have not been…”
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YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer by Baek, Seung-Woo, Mun, Jeong-Yeon, Jang, In-Hwan, Yang, Gi-Eun, Jeong, Mi-So, Kim, Seon-Kyu, Nam, Jong-Kil, Chu, In-Sun, Leem, Sun-Hee

“…Despite the availability of several treatments for non-muscle-invasive bladder cancer (NMIBC), many patients are still not responsive to treatments, and the…”
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