Search Results - "Chu, Hencelyn"
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Pre-clinical pharmacokinetics and anti-chlamydial activity of salicylidene acylhydrazide inhibitors of bacterial type III secretion
Published in Journal of antibiotics (01-08-2012)“…Salicylidene acylhydrazides belong to a class of compounds shown to inhibit bacterial type III secretion (T3S) in pathogenic Gram-negative bacteria. This class…”
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Journal Article -
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Identification of Concomitant Infection with Chlamydia trachomatis IncA-Negative Mutant and Wild-Type Strains by Genomic, Transcriptional, and Biological Characterizations
Published in Infection and Immunity (01-12-2008)“…Clinical isolates of Chlamydia trachomatis that lack IncA on their inclusion membrane form nonfusogenic inclusions and have been associated with milder,…”
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Journal Article -
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Host α-adducin is redistributed and localized to the inclusion membrane in Chlamydia-and Chlamydophila-infected cells
Published in Microbiology (Society for General Microbiology) (01-12-2008)“…A large-scale analysis of proteins involved in host-cell signalling pathways was performed using chlamydia-infected murine cells in order to identify host…”
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Journal Article -
4
Protection of Mice From a Chlamydia trachomatis Vaginal Infection Using a Salicylidene Acylhydrazide, a Potential Microbicide
Published in The Journal of infectious diseases (01-11-2011)“…The salicylidene acylhydrazide INP0341 inhibits growth of Chlamydia in HeLa cells, has negligible cell toxicity, and does not inhibit the growth of…”
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Journal Article -
5
Candidate vaginal microbicides with activity against Chlamydia trachomatis and Neisseria gonorrhoeae
Published in International journal of antimicrobial agents (01-08-2010)“…Abstract Vaginal microbicides with activity towards organisms that cause sexually transmitted infections have been proposed as a strategy to reduce…”
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Journal Article -
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Protection of mice from a chlamydia trachomatis vaginal infection using a salicylidene acylhydrazide, a potential Mmcrobicide
Published in The Journal of infectious diseases (2011)“…The salicylidene acylhydrazide INP0341 inhibits growth of Chlamydia in HeLa cells, has negligible cell toxicity, and does not inhibit the growth of…”
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Journal Article -
7
In vitro anti-HIV-1 activity of salicylidene acylhydrazide compounds
Published in International journal of antimicrobial agents (01-10-2012)“…Abstract Salicylidene acylhydrazide compounds have been shown to inhibit bacterial pathogens, including Chlamydia and Neisseria gonorrhoeae . If such compounds…”
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Journal Article -
8
Host {alpha}-adducin is redistributed and localized to the inclusion membrane in Chlamydia- and Chlamydophila-infected cells
Published in Microbiology (Society for General Microbiology) (01-12-2008)“…1 Department of Biomedical Sciences, College of Veterinary Medicine, Oregon State University, Corvallis, OR 97331-4804, USA 2 Department of Microbiology,…”
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Journal Article -
9
Candidate vaginal microbicides with activity against Chlamydia trachomatis and Neisseriagonorrhoeae
Published in International journal of antimicrobial agents (01-08-2010)“…Vaginal microbicides with activity towards organisms that cause sexually transmitted infections have been proposed as a strategy to reduce transmission…”
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Journal Article -
10
Analysis of chlamydial and host proteins associated with infection
Published 01-01-2007“…Chlamydiae are obligate intracellular bacteria that infect a variety of eukaryotic hosts and affect normal host processes. Within host cells, their…”
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Dissertation -
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Analysis of chlamydial and host proteins associated with infection
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Dissertation