Search Results - "Chu, David C K"

MeCP2 Controls an Epigenetic Pathway That Promotes Myofibroblast Transdifferentiation and Fibrosis by Mann, Jelena, Chu, David C.K, Maxwell, Aidan, Oakley, Fiona, Zhu, Nian–Ling, Tsukamoto, Hidekazu, Mann, Derek A

“…Background & Aims Myofibroblast transdifferentiation generates hepatic myofibroblasts, which promote liver fibrogenesis. The peroxisome proliferator-activated…”
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A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A by Zeybel, Müjdat, Luli, Saimir, Sabater, Laura, Hardy, Timothy, Oakley, Fiona, Leslie, Jack, Page, Agata, Moran Salvador, Eva, Sharkey, Victoria, Tsukamoto, Hidekazu, Chu, David C.K., Singh, Uma Sharan, Ponzoni, Mirco, Perri, Patrizia, Di Paolo, Daniela, Mendivil, Edgar J., Mann, Jelena, Mann, Derek A.

“…The progression of fibrosis in chronic liver disease is dependent upon hepatic stellate cells (HSCs) transdifferentiating to a myofibroblast-like phenotype…”
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Epigenetic downregulation of human disabled homolog 2 switches TGF-beta from a tumor suppressor to a tumor promoter by Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J

“…The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer…”
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Epigenetic downregulation of human disabled homolog 2 switches TGF-[Beta] from a tumor suppressor to a tumor promoter by Hannigan, Adèle, Smith, Paul, Kalna, Gabriela, Lo Nigro, Cristiana, Orange, Clare, O'Brien, Darren I, Shah, Reshma, Syed, Nelofer, Spender, Lindsay C, Herrera, Blanca, Thurlow, Johanna K, Lattanzio, Laura, Monteverde, Martino, Maurer, Meghan E, Buffa, Francesca M, Mann, Jelena, Chu, David C K, West, Catharine M L, Patridge, Max, Oien, Karin A, Cooper, Jonathan A, Frame, Margaret C, Harris, Adrian L, Hiller, Louise, Nicholson, Linda J, Gasco, Milena, Crook, Tim, Inman, Gareth J

“…The cytokine TGF-beta acts as a tumor suppressor in normal epithelial cells and during the early stages of tumorigenesis. During malignant progression, cancer…”
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SPECT imaging of herpes simplex virus type1 thymidine kinase gene expression by [(123)I]FIAU(1) by Choi, Seok Rye, Zhuang, Zhi-Ping, Chacko, Ann-Marie, Acton, Paul D, Tjuvajev-Gelovani, Juri, Doubrovin, Mikhai, Chu, David C K, Kung, Hank F

“…Introduction of suicide genes, such as herpes simplex virus type1 thymidine kinase (HSV1-tk), in tumor cells has provided a useful method for tumor gene…”
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