Search Results - "Chu, Chih‐Sheng"
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1
Interplay between CRP, Atherogenic LDL, and LOX-1 and Its Potential Role in the Pathogenesis of Atherosclerosis
Published in Clinical chemistry (Baltimore, Md.) (01-02-2016)“…Studies have shown that the classic acute-phase protein C-reactive protein (CRP) has proinflammatory effects on vascular cells and may play a causal role in…”
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2
Role of Low‐Density Lipoprotein in Early Vascular Aging Associated With Systemic Lupus Erythematosus
Published in Arthritis & rheumatology (Hoboken, N.J.) (01-06-2020)“…Objective Patients with systemic lupus erythematosus (SLE) often have atherosclerotic complications at a young age but normal low‐density lipoprotein (LDL)…”
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3
Human electronegative LDL induces mitochondrial dysfunction and premature senescence of vascular cells in vivo
Published in Aging cell (01-08-2018)“…Summary Dysregulation of plasma lipids is associated with age‐related cardiovascular diseases. L5, the most electronegative subfraction of chromatographically…”
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4
Increased APOE glycosylation plays a key role in the atherogenicity of L5 low‐density lipoprotein
Published in The FASEB journal (01-07-2020)“…Low‐density lipoprotein (LDL) is heterogeneous, composed of particles with variable atherogenicity. Electronegative L5 LDL exhibits atherogenic properties in…”
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The prognostic value of URR equals that of Kt/V for all-cause mortality in Taiwan after 10-year follow-up
Published in Scientific reports (01-06-2023)“…Kt/V and URR (urea reduction ratio) measurements represent dialysis adequacy. Single-pool Kt/V is theoretically a superior method and is recommended by the…”
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6
Affective Computing Based on Morphological Features of Photoplethysmography for Patients with Hypertension
Published in Sensors (Basel, Switzerland) (01-11-2022)“…Negative and positive emotions are the risk and protective factors for the cause and prognosis of hypertension. This study aimed to use five…”
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7
Range of L5 LDL levels in healthy adults and L5’s predictive power in patients with hyperlipidemia or coronary artery disease
Published in Scientific reports (08-08-2018)“…Electronegative L5 low-density lipoprotein (LDL) level may be a useful biomarker for predicting cardiovascular disease. We determined the range of plasma L5…”
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8
Electronegative Low-Density Lipoprotein L5 Induces Adipose Tissue Inflammation Associated With Metabolic Syndrome
Published in The journal of clinical endocrinology and metabolism (01-12-2017)“…Abstract Context Electronegative low-density lipoprotein (LDL) L5 is a naturally occurring, atherogenic entity found at elevated levels in the plasma of…”
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9
P2Y12 Inhibitor Monotherapy versus Conventional Dual Antiplatelet Therapy in Patients with Acute Coronary Syndrome after Percutaneous Coronary Intervention: A Meta-Analysis
Published in Pharmaceuticals (Basel, Switzerland) (01-02-2023)“…P2Y12 inhibitor monotherapy is a feasible alternative treatment for patients after percutaneous coronary intervention (PCI) in the modern era. Clinical trials…”
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10
Electronegative low‐density lipoprotein of patients with metabolic syndrome induces pathogenesis of aorta through disruption of the stimulated by retinoic acid 6 cascade
Published in Journal of diabetes investigation (01-05-2020)“…Aims/Introduction Electronegative low‐density lipoprotein (L5) is the most atherogenic fraction of low‐density lipoprotein and is elevated in people with…”
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11
Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases
Published in Biomedicines (29-11-2020)“…Dysregulation of glucose and lipid metabolism increases plasma levels of lipoproteins and triglycerides, resulting in vascular endothelial damage. Remarkably,…”
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Enhanced Sphingomyelinase Activity Contributes to the Apoptotic Capacity of Electronegative Low-Density Lipoprotein
Published in Journal of medicinal chemistry (11-02-2016)“…Sphingomyelinase (SMase) catalyzes the degradation of sphingomyelin to ceramide. In patients with metabolic syndrome or diabetes, circulating plasma ceramide…”
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13
Electronegative low density lipoprotein induces renal apoptosis and fibrosis: STRA6 signaling involved[S]
Published in Journal of lipid research (01-08-2016)“…Dyslipidemia has been proven to capably develop and aggravate chronic kidney disease. We also report that electronegative LDL (L5) is the most atherogenic LDL…”
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14
Local Augmented Angiotensinogen Secreted from Apoptotic Vascular Endothelial Cells Is a Vital Mediator of Vascular Remodelling
Published in PloS one (06-07-2015)“…Vascular remodelling is a critical vasculopathy found in atheromatous diseases and allograft failures. The local renin angiotensin system (RAS) has been…”
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15
Electronegative low-density lipoprotein increases C-reactive protein expression in vascular endothelial cells through the LOX-1 receptor
Published in PloS one (08-08-2013)“…Increased plasma C-reactive protein (CRP) levels are associated with the occurrence and severity of acute coronary syndrome. We investigated whether CRP can be…”
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16
VLDL from Metabolic Syndrome Individuals Enhanced Lipid Accumulation in Atria with Association of Susceptibility to Atrial Fibrillation
Published in International journal of molecular sciences (20-01-2016)“…Metabolic syndrome (MetS) represents a cluster of metabolic derangements. Dyslipidemia is an important factor in MetS and is related to atrial fibrillation…”
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17
The impact of estradiol and 1,25(OH)2D3 on metabolic syndrome in middle-aged Taiwanese males
Published in PloS one (28-03-2013)“…In addition to adipocytokines, estradiol (E2) and vitamin D have been reported to affect insulin sensitivity, glucose homeostasis and body weight. However,…”
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Clinical Significance of Electronegative Low-Density Lipoprotein Cholesterol in Atherothrombosis
Published in Biomedicines (30-07-2020)“…Despite the numerous risk factors for atherosclerotic cardiovascular diseases (ASCVD), cumulative evidence shows that electronegative low-density lipoprotein…”
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An Increased Plasma Level of ApoCIII-Rich Electronegative High-Density Lipoprotein May Contribute to Cognitive Impairment in Alzheimer's Disease
Published in Biomedicines (26-11-2020)“…High-density lipoprotein (HDL) plays a vital role in lipid metabolism and anti-inflammatory activities; a dysfunctional HDL impairs cholesterol efflux…”
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Factors Associated With In-hospital Mortality of Children With Acute Fulminant Myocarditis on Extracorporeal Membrane Oxygenation
Published in Frontiers in pediatrics (27-08-2020)“…Aim: To analyze the factors associated with in-hospital mortality of children with acute fulminant myocarditis on venoarterial extracorporeal membrane…”
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