Search Results - "Chu, Catherine J."
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The natural history of epilepsy in tuberous sclerosis complex
Published in Epilepsia (Copenhagen) (01-07-2010)“…Summary Background: Although epilepsy affects most patients with tuberous sclerosis complex (TSC), little is known about the natural history of epilepsy in…”
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Contemporary Profile of Seizures in Neonates: A Prospective Cohort Study
Published in The Journal of pediatrics (01-07-2016)“…Objective To determine the contemporary etiology, burden, and short-term outcomes of seizures in neonates monitored with continuous video-electroencephalogram…”
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3
Distinguishing between different percolation regimes in noisy dynamic networks with an application to epileptic seizures
Published in PLoS computational biology (01-06-2023)“…In clinical neuroscience, epileptic seizures have been associated with the sudden emergence of coupled activity across the brain. The resulting functional…”
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Seizures in Preterm Neonates: A Multicenter Observational Cohort Study
Published in Pediatric neurology (01-07-2017)“…Abstract Objective The purpose of this study was to characterize seizures among preterm neonates enrolled in the Neonatal Seizure Registry , a prospective…”
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Local and distant responses to single pulse electrical stimulation reflect different forms of connectivity
Published in NeuroImage (Orlando, Fla.) (15-08-2021)“…Measuring connectivity in the human brain involves innumerable approaches using both noninvasive (fMRI, EEG) and invasive (intracranial EEG or iEEG) recording…”
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6
Human seizures self-terminate across spatial scales via a critical transition
Published in Proceedings of the National Academy of Sciences - PNAS (18-12-2012)“…Why seizures spontaneously terminate remains an unanswered fundamental question of epileptology. Here we present evidence that seizures self-terminate via a…”
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Physiology of functional and effective networks in epilepsy
Published in Clinical neurophysiology (01-02-2015)“…Highlights • The relationships between functional and structural networks provide insights into brain abnormalities that are observed in epilepsy. • Functional…”
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The probability of seizures during EEG monitoring in critically ill adults
Published in Clinical neurophysiology (01-03-2015)“…Highlights • Seizures occurred in 27% of 625 acutely ill patients. Most were detected within the first 30 min. • The 72 h risk for seizures decays to <5% over…”
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The impact of hypsarrhythmia on infantile spasms treatment response: Observational cohort study from the National Infantile Spasms Consortium
Published in Epilepsia (Copenhagen) (01-12-2017)“…Summary Objective The multicenter National Infantile Spasms Consortium prospective cohort was used to compare outcomes and phenotypic features of patients with…”
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A semi-automated method for rapid detection of ripple events on interictal voltage discharges in the scalp electroencephalogram
Published in Journal of neuroscience methods (01-02-2017)“…•Spike-ripple events, in which fast oscillations co-occur with voltage discharges, can be detected automatically in the scalp EEG.•A combination of multiple…”
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Treatment Duration After Acute Symptomatic Seizures in Neonates: A Multicenter Cohort Study
Published in The Journal of pediatrics (01-02-2017)“…We aimed to define determinants of duration of treatment for acute symptomatic neonatal seizures in a contemporary multicenter observational cohort study…”
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12
Delta rhythmicity is a reliable EEG biomarker in Angelman syndrome: a parallel mouse and human analysis
Published in Journal of neurodevelopmental disorders (08-05-2017)“…Clinicians have qualitatively described rhythmic delta activity as a prominent EEG abnormality in individuals with Angelman syndrome, but this phenotype has…”
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Computational Evidence for a Competitive Thalamocortical Model of Spikes and Spindle Activity in Rolandic Epilepsy
Published in Frontiers in computational neuroscience (18-06-2021)“…Rolandic epilepsy (RE) is the most common idiopathic focal childhood epilepsy syndrome, characterized by sleep-activated epileptiform spikes and seizures and…”
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Physiological consequences of abnormal connectivity in a developmental epilepsy
Published in Annals of neurology (01-03-2015)“…Objective Many forms of epilepsy are associated with aberrant neuronal connections, but the relationship between such pathological connectivity and the…”
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15
Robust disruptions in electroencephalogram cortical oscillations and large-scale functional networks in autism
Published in BMC neurology (27-06-2015)“…Autism spectrum disorders (ASD) are increasingly prevalent and have a significant impact on the lives of patients and their families. Currently, the diagnosis…”
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Abnormal coherence and sleep composition in children with Angelman syndrome: a retrospective EEG study
Published in Molecular autism (27-04-2018)“…Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability, speech and motor impairments, epilepsy, abnormal sleep, and…”
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Preliminary evidence of a relationship between sleep spindles and treatment response in epileptic encephalopathy
Published in Annals of clinical and translational neurology (01-09-2023)“…Epileptic encephalopathy with spike-wave activation in sleep (EE-SWAS) is a challenging neurodevelopmental disease characterized by abundant epileptiform…”
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Source EEG reveals that Rolandic epilepsy is a regional epileptic encephalopathy
Published in NeuroImage clinical (01-01-2022)“…[Display omitted] •Children with RE have fewer spindles but they have typical time–frequency features.•Spindle deficits extend to multiple cortical regions in…”
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Delta power robustly predicts cognitive function in Angelman syndrome
Published in Annals of clinical and translational neurology (01-07-2021)“…Objective Angelman syndrome (AS) is a severe neurodevelopmental disorder caused by loss of function of the maternally inherited UBE3A gene in neurons…”
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Transient, developmental functional and structural connectivity abnormalities in the thalamocortical motor network in Rolandic epilepsy
Published in NeuroImage clinical (01-01-2022)“…•Children with active Rolandic epilepsy have increasing thalamocortical functional connectivity in the motor circuit with age.•Children with resolved Rolandic…”
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