Search Results - "Chu, Angel Ka Yan"
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Endosteal stem cells at the bone-blood interface: A double-edged sword for rapid bone formation: Bone marrow endosteal stem cells provide a robust source of bone-making osteoblasts both in normal and abnormal bone formation
Published in BioEssays (01-03-2024)“…Endosteal stem cells are a subclass of bone marrow skeletal stem cell populations that are particularly important for rapid bone formation occurring in growth…”
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Bone marrow endosteal stem cells dictate active osteogenesis and aggressive tumorigenesis
Published in Nature communications (25-04-2023)“…The bone marrow contains various populations of skeletal stem cells (SSCs) in the stromal compartment, which are important regulators of bone formation. It is…”
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Intercellular Interactions of an Adipogenic CXCL12‐Expressing Stromal Cell Subset in Murine Bone Marrow
Published in Journal of bone and mineral research (01-06-2021)“…ABSTRACT Bone marrow houses a multifunctional stromal cell population expressing C‐X‐C motif chemokine ligand 12 (CXCL12), termed CXCL12‐abundant reticular…”
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Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer
Published in Nature cancer (01-11-2020)“…Pancreatic ductal adenocarcinoma (PDA) is characterized by an immune-suppressive tumor microenvironment that renders it largely refractory to immunotherapy. We…”
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The fate of early perichondrial cells in developing bones
Published in Nature communications (28-11-2022)“…In endochondral bone development, bone-forming osteoblasts and bone marrow stromal cells have dual origins in the fetal cartilage and its surrounding…”
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Single-Cell Transcriptomic Analysis Reveals Developmental Relationships and Specific Markers of Mouse Periodontium Cellular Subsets
Published in Frontiers in dental medicine (01-08-2021)“…The periodontium is essential for supporting the functionality of the tooth, composed of diversity of mineralized and non-mineralized tissues such as the…”
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Endosteal stem cells at the bone‐blood interface: A double‐edged sword for rapid bone formation
Published in BioEssays (01-03-2024)“…Endosteal stem cells are a subclass of bone marrow skeletal stem cell populations that are particularly important for rapid bone formation occurring in growth…”
Get full text
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Abstract 3442: Multimodal mapping of the immune landscape in human pancreatic cancer
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Background: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer related death in the US. Unfortunately, recent clinical…”
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TET2 promotes tumor antigen presentation and T cell IFN-γ which is enhanced by vitamin C
Published in JCI insight (10-10-2024)“…Immune evasion by tumors is promoted by low T cell infiltration, ineffective T cell activity directed against the tumor and reduced tumor antigen presentation…”
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