Search Results - "Chruszcz, M"

Structure of aspartate β‐semialdehyde dehydrogenase from Francisella tularensis by Mank, N. J., Pote, S., Majorek, K.A., Arnette, A. K., Klapper, V. G., Hurlburt, B. K., Chruszcz, M.

“…Aspartate β‐semialdehyde dehydrogenase (ASADH) is an enzyme involved in the diaminopimelate pathway of lysine biosynthesis. It is essential for the viability…”
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IgE Antibody Binding Sites On Mite Group I Allergens Defined By X-ray Crystallography And Site-directed Mutagenesis by Pomés, A, Glesner, J, Vailes, L.D, Minor, W, Chruszcz, M, Chapman, M.D

“…Site-directed mutagenesis analysis of residues from epitopes identified by X-ray crystallography allows the location of amino acids important for…”
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Structural Analysis of Der f 1 and Der p 1 Allergen-Antibody Complexes Explains Cross-reactivity of Group 1 Allergens by Chruszcz, M, Chapman, M.D, Vailes, L.D, Pomés, A, Minor, W

“…In both allergens the epitope is not only formed by the same amino acids, but their conformations are also the same. [...]the amino acids forming the epitope…”
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To automate or not to automate: this is the question by Cymborowski, M, Klimecka, M, Chruszcz, M, Zimmerman, M. D, Shumilin, I. A, Borek, D, Lazarski, K, Joachimiak, A, Otwinowski, Z, Anderson, W, Minor, W

“…New protocols and instrumentation significantly boost the outcome of structural biology, which has resulted in significant growth in the number of deposited…”
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Crystal Structures of Der f 1, Der p 1 and a Der f 1 Allergen-Antibody Complex: Localization of Antibody Binding Epitopes by Chruszcz, M, Chapman, M.D, Stura, E.A, Vailes, L.D, Saint-Remy, J, Minor, W, Pomés, A

“…DNA encoding for Der f 1 has been mutated for expression of single epitope mutants in Pichia pastoris to analyze the effect of specific amino acids on IgE…”
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Structure of isochorismate synthase DhbC from Bacillus anthracis by Domagalski, M. J., Tkaczuk, K. L., Chruszcz, M., Skarina, T., Onopriyenko, O., Cymborowski, M., Grabowski, M., Savchenko, A., Minor, W.

“…The isochorismate synthase DhbC from Bacillus anthracis is essential for the biosynthesis of the siderophore bacillibactin by this pathogenic bacterium. The…”
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Structure of anabolic ornithine carbamoyltransferase from Campylobacter jejuni at 2.7 Å resolution by Shabalin, I. G., Porebski, P. J., Cooper, D. R., Grabowski, M., Onopriyenko, O., Grimshaw, S., Savchenko, A., Chruszcz, M., Minor, W.

“…Anabolic ornithine transcarbamoylase (aOTC) catalyzes the reaction between carbamoyl phosphate (CP) and l‐ornithine (ORN) to form l‐citrulline and phosphate in…”
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Crystal structure of 6-(4-difluoromethoxy-3-methoxyphenyl)-3(2H)- pyridazinone, C12H10F2N2O3 by Doyle C. R., Zimmerman M. D., Chruszcz M., Cymborowski M., Gawlicka-Chruszcz A., Minor W.

“…C12H10F2N2O3, monoclinic, P121/n1 (no. 14), a = 7.239(1) Å, b = 15.838(1) Å, c = 10.099(1) Å, β = 91.991(6)°, V = 1157.2 Å3, Z = 4, Rgt(F) = 0.033, wRref(F2) =…”
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Crystal structure of 6-(4-difluoromethoxy-3-methoxyphenyl)-3(2H)- pyridazinone, C12H10F2N2O3 by Doyle C. R., Zimmerman M. D., Chruszcz M., Cymborowski M., Gawlicka-Chruszcz A., Minor W.

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Double chromodomains cooperate to recognize the methylated histone H3 tail by Cymborowski, Marcin, Mi, Li-Zhi, Khorasanizadeh, Sepideh, Rastinejad, Fraydoon, Minor, Wladek, Clines, Katrina L, Kim, Youngchang, Flanagan, John F, Chruszcz, Maksymilian

“…Chromodomains are modules implicated in the recognition of lysine-methylated histone tails and nucleic acids. CHD (for chromo-ATPase/helicase-DNA-binding)…”
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Crystal Structures of Mite Allergens Der f 1 and Der p 1 Reveal Differences in Surface-Exposed Residues that May Influence Antibody Binding by Chruszcz, Maksymilian, Chapman, Martin D., Vailes, Lisa D., Stura, Enrico A., Saint-Remy, Jean-Marie, Minor, Wladek, Pomés, Anna

“…The group 1 mite allergens Der f 1 and Der p 1 are potent allergens excreted by Dermatophagoides farinae and Dermatophagoides pteronyssinus, respectively. The…”
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The tetramer structure of the Nervy homology two domain, NHR2, is critical for AML1/ETO's activity by Liu, Yizhou, Cheney, Matthew D., Gaudet, Justin J., Chruszcz, Maksymilian, Lukasik, Stephen M., Sugiyama, Daisuke, Lary, Jeff, Cole, James, Dauter, Zbyszek, Minor, Wladek, Speck, Nancy A., Bushweller, John H.

“…AML1/ETO is the chimeric protein resulting from the t(8;21) in acute myeloid leukemia. The Nervy homology 2 (NHR2) domain in ETO mediates oligomerization and…”
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Structure of aspartate [beta]-semialdehyde dehydrogenase from Francisella tularensis by Mank, N J, Pote, S, Majorek, KA, Arnette, A K, Klapper, V G, Hurlburt, B K, Chruszcz, M

“…Aspartate [beta]-semialdehyde dehydrogenase (ASADH) is an enzyme involved in the diaminopimelate pathway of lysine biosynthesis. It is essential for the…”
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Continua of Interactions between Pairs of Atoms in Molecular Crystals by Dominiak, Paulina M., Makal, Anna, Mallinson, Paul R., Trzcinska, Kinga, Eilmes, Julita, Grech, Eugeniusz, Chruszcz, Maksymilian, Minor, Władek, Woźniak, Krzysztof

“…The electron density distributions in crystals of five previously studied DMAN complexes and five Schiff bases (two new ones) have been analysed in terms of…”
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Crystal Structure of RNase T, an Exoribonuclease Involved in tRNA Maturation and End Turnover by Zuo, Yuhong, Zheng, Heping, Wang, Yong, Chruszcz, Maksymilian, Cymborowski, Marcin, Skarina, Tatiana, Savchenko, Alexei, Malhotra, Arun, Minor, Wladek

“…The 3′ processing of most bacterial precursor tRNAs involves exonucleolytic trimming to yield a mature CCA end. This step is carried out by RNase T, a member…”
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Crystal Structure of the MACPF Domain of Human Complement Protein C8a in Complex with the C8g Subunit by Slade, D J, Lovelace, L L, Chruszcz, M, Minor, W, Lebioda, L, Sodetz, J M

“…Human C8 is one of five complement components (C5b, C6, C7, C8, and C9) that assemble on bacterial membranes to form a porelike structure referred to as the…”
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Benefits of structural genomics for drug discovery research by Grabowski, Marek, Chruszcz, Maksymilian, Zimmerman, Matthew D, Kirillova, Olga, Minor, Wladek

“…While three dimensional structures have long been used to search for new drug targets, only a fraction of new drugs coming to the market has been developed…”
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Crystal structure of a covalent intermediate of endogenous human arylsulfatase A by Chruszcz, Maksymilian, Laidler, Piotr, Monkiewicz, Maciej, Ortlund, Eric, Lebioda, Lukasz, Lewinski, Krzysztof

“…The structures of human arylsulfatase A crystals soaked in solutions containing 4-methylumbelliferyl phosphate and O-phospho- dl-tyrosine have been determined…”
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Metal and small-molecule agent environment in macromolecules by Minor, W., Zheng, H., Chruszcz, M.

“…Abstract only…”
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First Principle Calculations for the Non-Heme Iron Centers of Lipoxygenases:  Geometrical and Spectral Properties by Borowski, Tomasz, Król, Marcin, Chruszcz, Maksymilian, Brocławik, Ewa

“…Lipoxygenases (LOs), which are non-heme-iron-containing enzymes, play a vital role in plant and mammalian organisms. Their active sites have been probed by…”
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