Search Results - "Christoulas, Dimitrios"
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Biology and treatment of myeloma related bone disease
Published in Metabolism, clinical and experimental (01-03-2018)“…Myeloma bone disease (MBD) is the most common complication of multiple myeloma (MM), resulting in skeleton-related events (SREs) such as severe bone pain,…”
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Sickle-cell disease and the heart: review of the current literature
Published in British journal of haematology (01-06-2012)“…Summary Sickle cell disease (SCD) is an inherited chronic haemolytic anaemia whose clinical manifestations arise from the tendency of the haemoglobin to…”
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Clinical features, outcome, and prognostic factors for survival and evolution to multiple myeloma of solitary plasmacytomas: A report of the Greek myeloma study group in 97 patients
Published in American journal of hematology (01-08-2014)“…Solitary plasmacytoma (SP) is a rare plasma cell dyscrasia characterized by the presence of bone or extramedullary plasma cell tumors. The treatment of choice…”
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Lenalidomide and dexamethasone for the treatment of refractory/relapsed multiple myeloma: dosing of lenalidomide according to renal function and effect on renal impairment
Published in European journal of haematology (01-07-2010)“…Objectives: Lenalidomide and dexamethasone (LenDex) is an active regimen for relapsed/refractory multiple myeloma (MM). However, there is limited data for the…”
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Increased angiogenesis and enhanced bone formation in patients with IgM monoclonal gammopathy and urticarial skin rash: new insight into the biology of Schnitzler syndrome
Published in Haematologica (Roma) (01-11-2012)“…Schnitzler syndrome is a rare plasma cell disorder the pathogenesis of which is still not fully understood. We evaluated the circulating levels of four major…”
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Pulmonary hypertension in patients with sickle cell/ β thalassemia : incidence and correlation with serum n-terminal pro-brain natriuretic peptide concentrations
Published in Haematologica (Roma) (01-06-2007)“…Pulmonary hypertension (PH) is increasingly observed in sickle cell disease (SCD) and beta-thalassemia (beta-thal), but there is no information on its…”
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Cystatin-C is an independent prognostic factor for survival in multiple myeloma and is reduced by bortezomib administration
Published in Haematologica (Roma) (01-03-2009)“…On behalf of the Greek Myeloma Study Group Correspondence: Evangelos Terpos, Department of Hematology and Medical Research, 251 General Air Force Hospital, 3…”
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Low Bone Mineral Density and High Bone Turnover in Patients With Non‐Hodgkin's Lymphoma (NHL) Who Receive Frontline Therapy: Results of a Multicenter Prospective Study
Published in HemaSphere (01-12-2019)“…Chemotherapy associated osteoporosis is a severe problem in patients with malignant diseases as it increases the risk for fractures and deteriorates quality of…”
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Serum Dickkopf-1 is increased and correlates with reduced bone mineral density in patients with thalassemia-induced osteoporosis. Reduction post-zoledronic acid administration
Published in Haematologica (Roma) (01-05-2009)“…1 Thalassemia Center, Laikon General Hospital, Athens 2 Department of Medical Research, 251 General Air Force Hospital, Athens 3 Department of Clinical…”
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The prognostic significance of chromosome 17 abnormalities in patients with myelodysplastic syndrome treated with 5‐azacytidine: Results from the Hellenic 5‐azacytidine registry
Published in Cancer medicine (Malden, MA) (01-05-2019)“…In patients with myelodysplastic syndrome (MDS), the prognostic significance of chromosome 17 abnormalities has not yet been fully elucidated, except for…”
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Effects of proteasome inhibitors on bone cancer
Published in BoneKEy reports (14-08-2013)“…Bone metastasis is a frequent complication of cancer, occurring in up to 70% of patients with advanced breast or prostate cancer, while bone disease is also…”
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Normalization of the serum angiopoietin-1 to angiopoietin-2 ratio reflects response in refractory/resistant multiple myeloma patients treated with bortezomib
Published in Haematologica (Roma) (01-03-2008)“…1 Department of Haematology, 251 General Air Force Hospital, Athens 2 Department of Haematology, National and Kapodistrian University of Athens School of…”
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The effect of prolonged administration of hydroxyurea on morbidity and mortality in adult patients with sickle cell syndromes: results of a 17-year, single-center trial (LaSHS)
Published in Blood (25-03-2010)“…The aim of this prospective study was to evaluate the long-term efficacy and safety of hydroxyurea (HU) in patients with sickle cell disease (SCD). Thirty-four…”
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Quantitative Diffusion-weighted Imaging of the Bone Marrow: An Adjunct Tool for the Diagnosis of a Diffuse MR Imaging Pattern in Patients with Multiple Myeloma
Published in Radiology (01-02-2017)“…Purpose To evaluate the apparent diffusion coefficients (ADCs) of magnetic resonance (MR) imaging patterns in the bone marrow of patients with multiple myeloma…”
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Elevated circulating sclerostin correlates with advanced disease features and abnormal bone remodeling in symptomatic myeloma: Reduction post-bortezomib monotherapy
Published in International journal of cancer (15-09-2012)“…Sclerostin is a Wingless and Int‐1 inhibitor, which is produced by osteocytes and inhibits osteoblast‐driven bone formation. Sclerostin is implicated in the…”
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Effect of induction therapy with lenalidomide, doxorubicin and dexamethasone on bone remodeling and angiogenesis in newly diagnosed multiple myeloma
Published in International journal of cancer (15-07-2019)“…There is limited data regarding the efficacy and safety of lenalidomide, adriamycin and dexamethasone (RAD) combination on newly diagnosed multiple myeloma…”
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Activin-A is elevated in patients with thalassemia major and double heterozygous sickle cell/beta-thalassemia and correlates with markers of hemolysis and bone mineral density
Published in Annals of hematology (01-07-2019)“…Despite the advances in the management of hemoglobinopathies, further insight into disease pathophysiology is necessary to improve our therapeutic approach…”
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The Chronic Kidney Disease Epidemiology Collaboration cystatin C (CKD-EPI-CysC) equation has an independent prognostic value for overall survival in newly diagnosed patients with symptomatic multiple myeloma; is it time to change from MDRD to CKD-EPI-CysC equations?
Published in European journal of haematology (01-10-2013)“…Objectives The estimation of glomerular filtration rate (eGFR) in multiple myeloma (MM) is based on equations that use serum creatinine (sCr), such as the…”
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