Search Results - "Christopher Hall, J"
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Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages
Published in Cell host & microbe (13-09-2012)“…Neutrophils are typically the first responders in host defense against invading pathogens, which they destroy by both oxidative and nonoxidative mechanisms…”
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The Diverse Roles of Phagocytes During Bacterial and Fungal Infections and Sterile Inflammation: Lessons From Zebrafish
Published in Frontiers in immunology (05-06-2020)“…The immediate and natural reaction to both infectious challenges and sterile insults (wounds, tissue trauma or crystal deposition) is an acute inflammatory…”
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Immunoresponsive Gene 1 Augments Bactericidal Activity of Macrophage-Lineage Cells by Regulating β-Oxidation-Dependent Mitochondrial ROS Production
Published in Cell metabolism (06-08-2013)“…Evidence suggests the bactericidal activity of mitochondria-derived reactive oxygen species (mROS) directly contributes to killing phagocytozed bacteria…”
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Applications of single-chain variable fragment antibodies in therapeutics and diagnostics
Published in Biotechnology advances (01-07-2009)“…Antibodies (Abs) are some of the most powerful tools in therapy and diagnostics and are currently one of the fastest growing classes of therapeutic molecules…”
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5
Transient inflammatory response mediated by interleukin-1β is required for proper regeneration in zebrafish fin fold
Published in eLife (23-02-2017)“…Cellular responses to injury are crucial for complete tissue regeneration, but their underlying processes remain incompletely elucidated. We have previously…”
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Antibody Binding to the O-Specific Antigen of Pseudomonas aeruginosa O6 Inhibits Cell Growth
Published in Antimicrobial agents and chemotherapy (24-03-2020)“…is an opportunistic pathogen that is inherently resistant to many antibiotics and represents an increasing threat due to the emergence of drug-resistant…”
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Infection-Responsive Expansion of the Hematopoietic Stem and Progenitor Cell Compartment in Zebrafish Is Dependent upon Inducible Nitric Oxide
Published in Cell stem cell (03-02-2012)“…Hematopoietic stem cells (HSCs) are rare multipotent cells that contribute to all blood lineages. During inflammatory stress, hematopoietic stem and progenitor…”
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Glyphosate resistance in Ambrosia trifida: Part 2. Rapid response physiology and non‐target‐site resistance
Published in Pest management science (01-05-2018)“…BACKGROUND The glyphosate‐resistant rapid response (GR RR) resistance mechanism in Ambrosia trifida is not due to target‐site resistance (TSR) mechanisms. This…”
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Quantitative characterization of the X‐ray beam at the Australian Synchrotron Imaging and Medical Beamline (IMBL)
Published in Journal of synchrotron radiation (01-01-2017)“…A critical early phase for any synchrotron beamline involves detailed testing, characterization and commissioning; this is especially true of a beamline as…”
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10
Live imaging of Runx1 expression in the dorsal aorta tracks the emergence of blood progenitors from endothelial cells
Published in Blood (12-08-2010)“…Blood cells of an adult vertebrate are continuously generated by hematopoietic stem cells (HSCs) that originate during embryonic life within the…”
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Extension of hydrogen borrowing alkylation reactions for the total synthesis of (-)-γ-lycorane
Published in Chemical communications (Cambridge, England) (19-04-2022)“…The total synthesis of (-)-γ-lycorane (10 steps) and synthesis of (±)-γ-lycorane (8 steps) was completed from cyclohexenone. A new two step hydrogen borrowing…”
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12
Zebrafish facial lymphatics develop through sequential addition of venous and non‐venous progenitors
Published in EMBO reports (01-05-2019)“…Lymphatic vessels are known to be derived from veins; however, recent lineage‐tracing experiments propose that specific lymphatic networks may originate from…”
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13
Evolution of Resistance to Auxinic Herbicides: Historical Perspectives, Mechanisms of Resistance, and Implications for Broadleaf Weed Management in Agronomic Crops
Published in Weed science (01-10-2011)“…Auxinic herbicides are widely used for control of broadleaf weeds in cereal crops and turfgrass. These herbicides are structurally similar to the natural plant…”
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In vivo neutralization of α-cobratoxin with high-affinity llama single-domain antibodies (VHHs) and a VHH-Fc antibody
Published in PloS one (22-07-2013)“…Small recombinant antibody fragments (e.g. scFvs and VHHs), which are highly tissue permeable, are being investigated for antivenom production as conventional…”
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Apple fruit copper amine oxidase isoforms: peroxisomal MdAO1 prefers diamines as substrates, whereas extracellular MdAO2 exclusively utilizes monoamines
Published in Plant and cell physiology (01-01-2015)“…4-Aminobutyrate (GABA) accumulates in apple fruit during controlled atmosphere storage. A potential source of GABA is the polyamine putrescine, which can be…”
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Macrophages enhance Vegfa-driven angiogenesis in an embryonic zebrafish tumour xenograft model
Published in Disease models & mechanisms (01-12-2018)“…Tumour angiogenesis has long been a focus of anti-cancer therapy; however, anti-angiogenic cancer treatment strategies have had limited clinical success…”
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Utility of the P19 suppressor of gene-silencing protein for production of therapeutic antibodies in Nicotiana expression hosts
Published in Plant biotechnology journal (01-12-2012)“…To study how the P19 suppressor of gene-silencing protein can be used effectively for the production of therapeutic glycoproteins, the following factors were…”
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Pyruvate Enolate Arylation and Alkylation: OBO Ester Protected Pyruvates as Useful Reagents in Organic Synthesis
Published in Organic letters (06-10-2017)“…A protected pyruvate equivalent is described that allows arylation and arylation/alkylation reactions to be performed at the methyl group. Utilization of the…”
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Epidermal cells help coordinate leukocyte migration during inflammation through fatty acid-fuelled matrix metalloproteinase production
Published in Nature communications (23-05-2014)“…In addition to satisfying the metabolic demands of cells, mitochondrial metabolism helps regulate immune cell function. To date, such cell-intrinsic…”
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Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling
Published in Blood (21-11-2013)“…Establishment and stabilization of endothelial tubes with patent lumens is vital during vertebrate development. Ras-interacting protein 1 (RASIP1) has been…”
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