Search Results - "Christopher, Josie A."

Inferring differential subcellular localisation in comparative spatial proteomics using BANDLE by Crook, Oliver M., Davies, Colin T. R., Breckels, Lisa M., Christopher, Josie A., Gatto, Laurent, Kirk, Paul D. W., Lilley, Kathryn S.

“…The steady-state localisation of proteins provides vital insight into their function. These localisations are context specific with proteins translocating…”
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CFTR Rescue by Lumacaftor (VX-809) Induces an Extensive Reorganization of Mitochondria in the Cystic Fibrosis Bronchial Epithelium by Braccia, Clarissa, Christopher, Josie A, Crook, Oliver M, Breckels, Lisa M, Queiroz, Rayner M L, Liessi, Nara, Tomati, Valeria, Capurro, Valeria, Bandiera, Tiziano, Baldassari, Simona, Pedemonte, Nicoletta, Lilley, Kathryn S, Armirotti, Andrea

“…Cystic Fibrosis (CF) is a genetic disorder affecting around 1 in every 3000 newborns. In the most common mutation, F508del, the defective anion channel, CFTR,…”
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Subcellular Transcriptomics and Proteomics: A Comparative Methods Review by Christopher, Josie A., Geladaki, Aikaterini, Dawson, Charlotte S., Vennard, Owen L., Lilley, Kathryn S.

“…The internal environment of cells is molecularly crowded, which requires spatial organization via subcellular compartmentalization. These compartments harbor…”
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Localization of Organelle Proteins by Isotope Tagging: Current status and potential applications in drug discovery research by Elzek, Mohamed A.W., Christopher, Josie A., Breckels, Lisa M., Lilley, Kathryn S.

“…Spatial proteomics has provided important insights into the relationship between protein function and subcellular location. Localization of Organelle Proteins…”
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Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemia by Borek, Weronika E., Nobre, Luis, Pedicona, S. Federico, Campbell, Amy E., Christopher, Josie A., Nawaz, Nazrath, Perkins, David N., Moreno-Cardoso, Pedro, Kelsall, Janet, Ferguson, Harriet R., Patel, Bela, Gallipoli, Paolo, Arruda, Andrea, Ambinder, Alex J., Thompson, Andrew, Williamson, Andrew, Ghiaur, Gabriel, Minden, Mark D., Gribben, John G., Britton, David J., Cutillas, Pedro R., Dokal, Arran D.

“…Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with intensive…”
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Phosphoproteomics predict response to midostaurin plus chemotherapy in independent cohorts of FLT3-mutated acute myeloid leukaemiaResearch in context by Weronika E. Borek, Luis Nobre, S. Federico Pedicona, Amy E. Campbell, Josie A. Christopher, Nazrath Nawaz, David N. Perkins, Pedro Moreno-Cardoso, Janet Kelsall, Harriet R. Ferguson, Bela Patel, Paolo Gallipoli, Andrea Arruda, Alex J. Ambinder, Andrew Thompson, Andrew Williamson, Gabriel Ghiaur, Mark D. Minden, John G. Gribben, David J. Britton, Pedro R. Cutillas, Arran D. Dokal

“…Background: Acute myeloid leukaemia (AML) is a bone marrow malignancy with poor prognosis. One of several treatments for AML is midostaurin combined with…”
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