Search Results - "Christoffels, A"

Understanding biobanking : an assessment of the public engagement speaking book intervention Biobanking and Me by Luus, R., Anderson, D., Christoffels, A., Bedeker, A., Mgwatyu, Y., Blignaut, R., Lose, T.

“…Background. Meaningful engagement with donors of biological samples intended for human-sample biobanking increases knowledge, and allows donors to make…”
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Exploring the potential of T7 bacteriophage protein Gp2 as a novel inhibitor of mycobacterial RNA polymerase by du Plessis, J., Cloete, R., Burchell, L., Sarkar, P., Warren, R.M., Christoffels, A., Wigneshweraraj, S., Sampson, S.L.

“…Over the past six decades, there has been a decline in novel therapies to treat tuberculosis, while the causative agent of this disease has become increasingly…”
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Antimalarial drug development from phytomedicine: Chemoinformatic and pharmacological studies by Egieyeh, S.A, Syce, J, Malan, S, Christoffels, A

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Database for exploration of functional context of genes implicated in ovarian cancer by Kaur, Mandeep, Radovanovic, Aleksandar, Essack, Magbubah, Schaefer, Ulf, Maqungo, Monique, Kibler, Tracey, Schmeier, Sebastian, Christoffels, Alan, Narasimhan, Kothandaraman, Choolani, Mahesh, Bajic, Vladimir B

“…Ovarian cancer (OC) is becoming the most common gynecological cancer in developed countries and the most lethal gynecological malignancy. It is also the fifth…”
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Cyprinid gonad differentiation: A comparative genomic study by Bartfai, R., Wang, X., Sreenivasan, R., Cai, M., Srinivasan, H., Hossain, M.S., Komen, J., Christoffels, A., Orban, L.

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A comprehensive approach to clustering of expressed human gene sequence: the sequence tag alignment and consensus knowledge base by Miller, R T, Christoffels, A G, Gopalakrishnan, C, Burke, J, Ptitsyn, A A, Broveak, T R, Hide, W A

“…The expressed human genome is being sequenced and analyzed by disparate groups producing disparate data. The majority of the identified coding portion is in…”
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STACK: Sequence Tag Alignment and Consensus Knowledgebase by Christoffels, A.

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Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes by Christoffels, Alan, Koh, Esther G L, Chia, Jer-Ming, Brenner, Sydney, Aparicio, Samuel, Venkatesh, Byrappa

“…With about 24,000 extant species, teleosts are the largest group of vertebrates. They constitute more than 99% of the ray-finned fishes (Actinopterygii) that…”
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Whole-Genome Shotgun Assembly and Analysis of the Genome of Fugu rubripes by Aparicio, Samuel, Chapman, Jarrod, Stupka, Elia, Putnam, Nik, Chia, Jer-ming, Dehal, Paramvir, Christoffels, Alan, Rash, Sam, Hoon, Shawn, Smit, Arian, Maarten D. Sollewijn Gelpke, Roach, Jared, Oh, Tania, Ho, Isaac Y., Wong, Marie, Detter, Chris, Verhoef, Frans, Predki, Paul, Tay, Alice, Lucas, Susan, Richardson, Paul, Smith, Sarah F., Clark, Melody S., Yvonne J. K. Edwards, Doggett, Norman, Zharkikh, Andrey, Tavtigian, Sean V., Pruss, Dmitry, Barnstead, Mary, Evans, Cheryl, Baden, Holly, Powell, Justin, Glusman, Gustavo, Rowen, Lee, Hood, Leroy, Tan, Y. H., Elgar, Greg, Hawkins, Trevor, Venkatesh, Byrappa, Rokhsar, Daniel, Brenner, Sydney

“…The compact genome of Fugu rubripes has been sequenced to over 95% coverage, and more than 80% of the assembly is in multigene-sized scaffolds. In this…”
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GOBLET: the Global Organisation for Bioinformatics Learning, Education and Training by Attwood, Teresa K, Atwood, Teresa K, Bongcam-Rudloff, Erik, Brazas, Michelle E, Corpas, Manuel, Gaudet, Pascale, Lewitter, Fran, Mulder, Nicola, Palagi, Patricia M, Schneider, Maria Victoria, van Gelder, Celia W G

“…In recent years, high-throughput technologies have brought big data to the life sciences. The march of progress has been rapid, leaving in its wake a demand…”
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Understanding biobanking: An assessment of the public engagement speaking book intervention Biobanking and Me by Bedeker, A, Anderson, D, Lose, T, Mgwatyu, Y, Luus, R, Blignaut, R, Christoffels, A

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Extensive expansion of the claudin gene family in the teleost fish, Fugu rubripes by Loh, Yong Hwee, Christoffels, Alan, Brenner, Sydney, Hunziker, Walter, Venkatesh, Byrappa

“…In humans, the claudin superfamily consists of 19 homologous proteins that commonly localize to tight junctions of epithelial and endothelial cells. Besides…”
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DDPC: Dragon Database of Genes associated with Prostate Cancer by Maqungo, Monique, Kaur, Mandeep, Kwofie, Samuel K, Radovanovic, Aleksandar, Schaefer, Ulf, Schmeier, Sebastian, Oppon, Ekow, Christoffels, Alan, Bajic, Vladimir B

“…Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms…”
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Bioinformatic prediction of microRNA targets in Anopheles gambiae: towards an understanding of parasitic control by blood-sucking mosquito by Ali, M., Ganesh, A., Christoffels, A.

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eVOC: a controlled vocabulary for unifying gene expression data by Kelso, Janet, Visagie, Johann, Theiler, Gregory, Christoffels, Alan, Bardien, Soraya, Smedley, Damian, Otgaar, Darren, Greyling, Gary, Jongeneel, C Victor, McCarthy, Mark I, Hide, Tania, Hide, Winston

“…Expression data contribute significantly to the biological value of the sequenced human genome, providing extensive information about gene structure and the…”
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Comparative genomics in cyprinids: common carp ESTs help the annotation of the zebrafish genome by Christoffels, Alan, Bartfai, Richard, Srinivasan, Hamsa, Komen, Hans, Orban, Laszlo

“…Automatic annotation of sequenced eukaryotic genomes integrates a combination of methodologies such as ab-initio methods and alignment of homologous genes…”
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STACK: Sequence Tag Alignment and Consensus Knowledgebase by Christoffels, A, van Gelder, A, Greyling, G, Miller, R, Hide, T, Hide, W

“…STACK is a tool for detection and visualisation of expressed transcript variation in the context of developmental and pathological states. The datasystem…”
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Evolution and Structural Analyses of Glossina morsitans (Diptera; Glossinidae) Tetraspanins by Murungi, Edwin K, Kariithi, Henry M, Adunga, Vincent, Obonyo, Meshack, Christoffels, Alan

“…Tetraspanins are important conserved integral membrane proteins expressed in many organisms. Although there is limited knowledge about the full repertoire,…”
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Hox Gene Clusters in the Indonesian Coelacanth, Latimeria menadoensis by Esther G. L. Koh, Lam, Kevin, Christoffels, Alan, Erdmann, Mark V., Brenner, Sydney, Venkatesh, Byrappa

“…The Hox genes encode transcription factors that play a key role in specifying body plans of metazoans. They are organized into clusters that contain up to 13…”
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Assessment of the parallelization approach of d2_cluster for high-performance sequence clustering by Carpenter, John E., Christoffels, Alan, Weinbach, Yael, Hide, Winston A.

“…The exponential increase in expressed sequence tag (EST) sequence data amplifies the computational cost of clustering sequences such that new algorithms are…”
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