Search Results - "Christoffel, Volker"
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In vitro assays for bioactivity-guided isolation of endocrine active compounds in Vitex agnus-castus
Published in Maturitas (01-11-2006)“…Extracts of Vitex agnus-castus (VAC) are used for the treatment of premenstrual symptoms. The mechanism of action was proposed to be dopaminergic and…”
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Apigenin drives the production of reactive oxygen species and initiates a mitochondrial mediated cell death pathway in prostate epithelial cells
Published in The Prostate (01-05-2005)“…BACKGROUND Phytoestrogens may reduce tumorigenesis in prostate cancer. We screened five phytoestrogens for their effect on cell growth and apoptosis in PWR‐1E,…”
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Cannabidiol revisited
Published in IUCrData (28-02-2017)“…The crystal structure of cannabidiol, C 21 H 30 O 2 , {systematic name: 2-[(1 R ,6 R )-3-methyl-6-(prop-1-en-2-yl)cyclohex-2-enyl]-5-pentylbenzene-1,3-diol},…”
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Step by step removal of hyperforin and hypericin: activity profile of different Hypericum preparations in behavioral models
Published in Life sciences (1973) (20-06-2003)“…Herbal extracts of Hypericum perfora tum L. (St. John's wort, SJW) are now successfully competing for status as a standard antidepressant therapy. Because of…”
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In vitro effects of the Cimicifuga racemosa extract BNO 1055
Published in Maturitas (14-03-2003)“…Objectives: Extracts of Black cohosh ( Cimicifuga racemosa or CR) have been used for the treatment of climacteric complaints since decades. Efficacy,…”
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Journal Article Conference Proceeding -
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Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer
Published in Carcinogenesis (New York) (01-08-2005)“…Isoflavones have been shown to exert antiproliferative effects on cancer cells by steroid receptor signaling. In this study, we demonstrate the potential of…”
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Evidence for estrogen receptor beta-selective activity of Vitex agnus-castus and isolated flavones
Published in Planta medica (01-10-2003)“…Recent cell culture experiments indicated that extracts of Vitex agnus-castus (VAC) may contain yet unidentified phytoestrogens. Estrogenic actions are…”
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Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro
Published in The Journal of urology (01-12-2004)“…Phytoestrogens are nonsteroidal plant derived compounds with estrogenic activity that have been implicated in protecting against prostate cancer progression…”
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Cimicifuga extract BNO 1055: reduction of hot flushes and hints on antidepressant activity
Published in Maturitas (14-03-2003)“…Ethanolic- and isopropanolic-aqueous extracts of Cimicifuga racemosa are used for the treatment of climacteric complaints. As hot flushes and psychic…”
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Journal Article Conference Proceeding -
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The flavonoid apigenin inhibits the proliferation of prostatic stromal cells via the MAPK-pathway and cell-cycle arrest in G1/S
Published in Maturitas (01-11-2006)“…Phytoestrogen apigenin, a member of flavonoids, has been described for its ability to induce growth arrest in carcinomas of colon, breast and prostate. In…”
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Journal Article Conference Proceeding -
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Phytoestrogens: endocrine disrupters or replacement for hormone replacement therapy?
Published in Maturitas (01-09-2008)“…This review presents findings with clear statements from the literature as well as own results of effects of soy, red clover and their isoflavones as well as…”
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Phytoestrogens: endocrine disrupters or replacement for hormone replacement therapy?
Published in Maturitas (14-03-2003)“…Objectives: This review presents findings with clear statements from the literature as well as own results of effects of soy, red clover and their isoflavones…”
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Journal Article Conference Proceeding -
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Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: discrimination between drug and ethanol effects
Published in Planta medica (01-08-1999)“…The effect of an extract of Thymus vulgaris on induced spasms was investigated on guinea-pig trachea preparations. By the experimental setup used, effects of…”
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Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays
Published in Planta medica (01-05-2005)“…The aim of this study was to identify genomic aberrations in endometrial cancer cells treated with the phyto-estrogenic compounds tectorigenin, irigenin and…”
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Reprint of Phytoestrogens: endocrine disrupters or replacement for hormone replacement therapy?
Published in Maturitas (2008)“…Abstract Objectives: This review presents findings with clear statements from the literature as well as own results of effects of soy, red clover and their…”
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Evidence for selective estrogen receptor modulator activity in a black cohosh (Cimicifuga racemosa) extract: comparison with estradiol-17beta
Published in European journal of endocrinology (01-10-2003)“…Some phytoestrogens are believed to have selective estrogen receptor modulator (SERM) activity with no action in the uterus but beneficial effects in the…”
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A phosphodiester bridge between two arabinose residues as a structural element of an extracellular glycöprotein of Volvox carteri
Published in European journal of biochemistry (01-05-1989)“…The sulphated glycoprotein SSG 185 is the monomeric precursor of a highly aggregated structural element in the extracellular matrix of the multicellular green…”
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