Search Results - "Christof M. Niemeyer"
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Semisynthetic DNA-Protein Conjugates for Biosensing and Nanofabrication
Published in Angewandte Chemie (International ed.) (08-02-2010)“…Conjugation with artificial nucleic acids allows proteins to be modified with a synthetically accessible, robust tag. This attachment is addressable in a…”
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DNA Origami: The Art of Folding DNA
Published in Angewandte Chemie International Edition (02-01-2012)“…The advent of DNA origami technology greatly simplified the design and construction of nanometer‐sized DNA objects. The self‐assembly of a DNA‐origami…”
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Cascades in Compartments: En Route to Machine‐Assisted Biotechnology
Published in Angewandte Chemie International Edition (23-10-2017)“…Biological compartmentalization is a fundamental principle of life that allows cells to metabolize, propagate, or communicate with their environment. Much…”
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Assembly and Purification of Enzyme-Functionalized DNA Origami Structures
Published in Angewandte Chemie International Edition (01-06-2015)“…The positioning of enzymes on DNA nanostructures for the study of spatial effects in interacting biomolecular assemblies requires chemically mild…”
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Chemical Strategies for Generating Protein Biochips
Published in Angewandte Chemie (International ed.) (01-12-2008)“…Protein biochips are at the heart of many medical and bioanalytical applications. Increasing interest has been focused on surface activation and subsequent…”
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Rational Design of DNA Nanoarchitectures
Published in Angewandte Chemie International Edition (13-03-2006)“…DNA has many physical and chemical properties that make it a powerful material for molecular constructions at the nanometer length scale. In particular, its…”
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Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
Published in Angewandte Chemie International Edition (19-11-2001)“…Based on fundamental chemistry, biotechnology and materials science have developed over the past three decades into today's powerful disciplines which allow…”
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Self‐Assembling All‐Enzyme Hydrogels for Flow Biocatalysis
Published in Angewandte Chemie International Edition (21-12-2018)“…Continuous flow biocatalysis is an emerging field of industrial biotechnology that uses enzymes immobilized in flow channels for the production of value‐added…”
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Cultivation of Exoelectrogenic Bacteria in Conductive DNA Nanocomposite Hydrogels Yields a Programmable Biohybrid Materials System
Published in ACS applied materials & interfaces (01-04-2020)“…The use of living microorganisms integrated within electrochemical devices is an expanding field of research, with applications in microbial fuel cells,…”
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An Orthogonal Covalent Connector System for the Efficient Assembly of Enzyme Cascades on DNA Nanostructures
Published in Small (Weinheim an der Bergstrasse, Germany) (01-12-2021)“…Combining structural DNA nanotechnology with the virtually unlimited variety of enzymes offers unique opportunities for generating novel biocatalytic devices…”
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Applications of Protein Biochips in Biomedical and Biotechnological Research
Published in Angewandte Chemie (International ed.) (05-10-2009)“…Progress in the development of protein-immobilization strategies and methods has made protein biochips increasingly accessible. The integration of these assay…”
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Orthogonal Protein Decoration of DNA Origami
Published in Angewandte Chemie (International ed.) (03-12-2010)“…If the face fits: Self‐labeling fusion proteins have been used for the site‐specific decoration of DNA origami. This method even allows individual faces of the…”
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13
On the Generation of Free Radical Species from Quantum Dots
Published in Small (Weinheim an der Bergstrasse, Germany) (01-07-2005)“…Radical discoveries? Semiconductor quantum dots (QDs) produce free radicals upon UV irradiation in aqueous solution. While CdS QDs generate superoxide and…”
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14
Carbon-nanotube reinforcement of DNA-silica nanocomposites yields programmable and cell-instructive biocoatings
Published in Nature communications (04-12-2019)“…Biomedical applications require substrata that allow for the grafting, colonization and control of eukaryotic cells. Currently available materials are often…”
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15
Designed Intercalators for Modification of DNA Origami Surface Properties
Published in Chemistry : a European journal (22-06-2015)“…The modification of the backbone properties of DNA origami nanostructures through noncovalent interactions with designed intercalators, based on acridine…”
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Biocatalytic Foams from Microdroplet-Formulated Self-Assembling Enzymes
Published in Advanced materials (Weinheim) (01-09-2023)“…Industrial biocatalysis plays an important role in the development of a sustainable economy, as enzymes can be used to synthesize an enormous range of complex…”
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Orthogonal Protein Decoration of DNA Nanostructures
Published in Small (Weinheim an der Bergstrasse, Germany) (18-11-2011)“…The development of robust DNA–protein coupling techniques is mandatory for applications of DNA nanostructures in biomedical diagnostics, fundamental…”
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18
Apoenzyme Reconstitution as a Chemical Tool for Structural Enzymology and Biotechnology
Published in Angewandte Chemie (International ed.) (16-02-2009)“…Enzymes with artificial cofactors: Nondiffusible organic cofactors of enzymes can often be replaced by artifical analogues to generate semisynthetic enzymes…”
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An Immobilised Silicon‐Carbon Bond‐Forming Enzyme for Anaerobic Flow Biocatalysis
Published in ChemCatChem (05-05-2023)“…The recent development of tailored cytochrome enzymes has enabled “new‐to‐nature” reactivities, such as the biocatalytic formation of carbon‐silicon bonds…”
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Microfluidic Chips for Life Sciences—A Comparison of Low Entry Manufacturing Technologies
Published in Small (Weinheim an der Bergstrasse, Germany) (01-08-2019)“…Microfluidic water‐in‐oil droplets are a versatile tool for biological and biochemical applications due to the advantages of extremely small monodisperse…”
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