Search Results - "Christodoulou, S"

The 1,2,3-triazole ring as a bioisostere in medicinal chemistry by Bonandi, Elisa, Christodoulou, Michael S., Fumagalli, Gaia, Perdicchia, Dario, Rastelli, Giulio, Passarella, Daniele

“…•Triazoles mimic different functional groups, resulting optimal bioisosteres for the synthesis of new active molecules.•Triazoles present a marked stability…”
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Vitamin D and Bone Disease by Drosos, G., Ververidis, A., Goula, T., Christodoulou, S.

“…Vitamin D is important for normal development and maintenance of the skeleton. Hypovitaminosis D adversely affects calcium metabolism, osteoblastic activity,…”
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Exploration of Novel Scaffolds Targeting Cytochrome b of Pyricularia oryzae by Pinna, Cecilia, Laurenzi, Tommaso, Forlani, Fabio, Palazzolo, Luca, Nolan, Claire Beatrice, Christodoulou, Michael S, Cortesi, Paolo, Pinto, Andrea, Eberini, Ivano, Kunova, Andrea, Dallavalle, Sabrina

“…The fulfilment of the European "Farm to Fork" strategy requires a drastic reduction in the use of "at risk" synthetic pesticides; this exposes vulnerable…”
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Quantitative live cell imaging of a tauopathy model enables the identification of a polypharmacological drug candidate that restores physiological microtubule interaction by Pinzi, Luca, Conze, Christian, Bisi, Nicolo, Torre, Gabriele Dalla, Soliman, Ahmed, Monteiro-Abreu, Nanci, Trushina, Nataliya I., Krusenbaum, Andrea, Dolouei, Maryam Khodaei, Hellwig, Andrea, Christodoulou, Michael S., Passarella, Daniele, Bakota, Lidia, Rastelli, Giulio, Brandt, Roland

“…Tauopathies such as Alzheimer’s disease are characterized by aggregation and increased phosphorylation of the microtubule-associated protein tau. Tau’s…”
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Targeting Ovarian Cancer with Chalcone Derivatives: Cytotoxicity and Apoptosis Induction in HGSOC Cells by Merve Aydin, Elif, Canıtez, İdil Su, Colombo, Eleonora, Princiotto, Salvatore, Passarella, Daniele, Dallavalle, Sabrina, Christodoulou, Michael S, Durmaz Şahin, Irem

“…Ovarian cancer ranks as the eighth most prevalent form of cancer in women across the globe and stands as the third most frequent gynecological cancer,…”
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An early evaluation of translocation actions for endangered plant species on Mediterranean islands by Fenu, Giuseppe, Bacchetta, Gianluigi, Charalambos, S. Christodoulou, Fournaraki, Christini, Giusso del Galdo, Gian Pietro, Gotsiou, Panagiota, Kyratzis, Angelos, Piazza, Carole, Vicens, Magdalena, Pinna, Maria Silvia, de Montmollin, Bertrand

“…In situ conservation is widely considered a primary conservation strategy. Plant translocation, specifically, represents an important tool for reducing the…”
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Correlation between Perturbation of Redox Homeostasis and Antibiofilm Capacity of Phytochemicals at Non-Lethal Concentrations by Christodoulou, Michael S, Villa, Federica, Pinto, Andrea, Cappitelli, Francesca

“…Biofilms are the multicellular lifestyle of microorganisms and are present on potentially every type of biotic or abiotic surface. Detrimental biofilms are…”
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A Common Approach to the Conservation of Threatened Island Vascular Plants: First Results in the Mediterranean Basin by Fenu, Giuseppe, Bacchetta, Gianluigi, Christodoulou, Charalambos S., Cogoni, Donatella, Fournaraki, Christini, Gian Pietro, Giusso del Galdo, Gotsiou, Panagiota, Kyratzis, Angelos, Piazza, Carole, Vicens, Magdalena, de Montmollin, Bertrand

“…The Mediterranean islands represent a center of vascular plant diversity featuring a high rate of endemic richness. Such richness is highly threatened,…”
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Using threatened plant species to identify conservation gaps and opportunities on the island of Cyprus by Christodoulou, C. S., Griffiths, G. H., Vogiatzakis, I. N.

“…The cornerstone of EU nature conservation, the Natura 2000 (N2K) network is far from complete in many EU countries, including Cyprus, particularly where new…”
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Biological Properties of New Chiral 2-Methyl-5,6,7,8-tetrahydroquinolin-8-amine-based Compounds by Facchetti, Giorgio, Christodoulou, Michael S, Mendoza, Lina Barragán, Cusinato, Federico, Dalla Via, Lisa, Rimoldi, Isabella

“…The synthesis of a small library of 8-substituted 2-methyl-5,6,7,8-tetrahydroquinoline derivatives is presented. All the compounds were tested for their…”
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Spontaneous miscarriages in patients with bladder pain syndrome/interstitial cystitis - effect of stress on inflammation? by Theoharides, P C, Christodoulou, S, Athanasiou, A

“…Interstitial cystitis/painful bladder syndrome (IC/PBS) affects mostly women and is characterized by pelvic pain or pressure and frequency of voiding in the…”
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Vancomycin-Iridium (III) Interaction: An Unexplored Route for Enantioselective Imine Reduction by Facchetti, Giorgio, Pellegrino, Sara, Bucci, Raffaella, Nava, Donatella, Gandolfi, Raffaella, Christodoulou, Michael S, Rimoldi, Isabella

“…The chiral structure of antibiotic vancomycin (Van) was exploited as an innovative coordination sphere for the preparation of an IrCp* based hybrid catalysts…”
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Fatty Acids/Tetraphenylethylene Conjugates: Hybrid AIEgens for the Preparation of Peptide-Based Supramolecular Gels by Impresari, Elisa, Bossi, Alberto, Lumina, Edoardo Mario, Ortenzi, Marco Aldo, Kothuis, Josine Marie, Cappelletti, Graziella, Maggioni, Daniela, Christodoulou, Michael S, Bucci, Raffaella, Pellegrino, Sara

“…Aggregation-induced emissive materials are gaining particular attention in the last decades due to their wide application in different fields, from optical…”
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Design and Synthesis of Hsp90 Inhibitors with B‐Raf and PDHK1 Multi‐Target Activity by Pinzi, Luca, Foschi, Francesca, Christodoulou, Michael S., Passarella, Daniele, Rastelli, Giulio

“…The design of multi‐target ligands has become an innovative approach for the identification of effective therapeutic treatments against complex diseases, such…”
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Management Implications at a Protected, Peri-Urban, Salt Lake Ecosystem: The Case of Larnaca’s Salt Lakes (Cyprus) by Bekri, Eleni S., Kokkoris, Ioannis P., Christodoulou, Charalambos S., Sophocleous-Lemonari, Antonia, Dimopoulos, Panayotis

“…Larnaca’s salt lakes constitute one of the most important protected areas in Cyprus and in the southeast Mediterranean. It is in continuity with the urban area…”
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Chalcone Derivatives Activate and Desensitize the Transient Receptor Potential Ankyrin 1 Cation Channel, Subfamily A, Member 1 TRPA1 Ion Channel: Structure-Activity Relationships in vitro and Anti-Nociceptive and Anti-inflammatory Activity in vivo by Moriello, Aniello Schiano, Luongo, Livio, Guida, Francesca, Christodoulou, Michael S, Perdicchia, Dario, Maione, Sabatino, Passarella, Daniele, Marzo, Vincenzo Di, Petrocellis, Luciano De

“…Eleven compounds belonging to the chalcone family were tested for their ability to activate and subsequently desensitize the rat transient receptor potential…”
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Asymmetric Hydrogenation of 1-aryl substituted-3,4-Dihydroisoquinolines with Iridium Catalysts Bearing Different Phosphorus-Based Ligands by Giorgio Facchetti, Michael S. Christodoulou, Eleonora Binda, Marco Fusè, Isabella Rimoldi

“…Starting from the chiral 5,6,7,8-tetrahydroquinolin-8-ol core, a series of amino-phosphorus-based ligands was realized. The so-obtained amino-phosphine ligand…”
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Nanolipid-Trehalose Conjugates and Nano-Assemblies as Putative Autophagy Inducers by Colombo, Eleonora, Biocotino, Michele, Frapporti, Giulia, Randazzo, Pietro, Christodoulou, Michael S, Piccoli, Giovanni, Polito, Laura, Seneci, Pierfausto, Passarella, Daniele

“…The disaccharide trehalose is an autophagy inducer, but its pharmacological application is severely limited by its poor pharmacokinetics properties. Thus,…”
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Micellization Behavior of Complex Comblike Block Copolymer Architectures by Zamurovic, M, Christodoulou, S, Vazaios, A, Iatrou, E, Pitsikalis, M, Hadjichristidis, N

“…Complex comblike block copolymers of various architectures containing polystyrene, PS, and polyisoprene, PI, or polybutadiene, PB, components were synthesized…”
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Natural Products and Cancer Stem Cells by Marucci, Cristina, Fumagalli, Gaia, Calogero, Francesco, Silvani, Alessandra, Christodoulou, Michael S, Martinet, Nadine, Passarella, Daniele

“…The development of modern technologies casts a new light on the natural products as an invaluable source of lead compounds that could guide drug discovery…”
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