Search Results - "Christine, Wolschke"

Comparison of immune reconstitution between anti-T-lymphocyte globulin and posttransplant cyclophosphamide as acute graft-versus-host disease prophylaxis in allogeneic myeloablative peripheral blood stem cell transplantation by Massoud, Radwan, Gagelmann, Nico, Fritzsche-Friedland, Ulrike, Zeck, Gaby, Heidenreich, Silke, Wolschke, Christine, Ayuk, Francis, Christopeit, Maximilian, Kröger, Nicolaus

“…Anti-T-cell lymphocyte globulin (ATLG) and posttransplant cyclophosphamide (PTCy) are now widely used strategies to prevent graft-versus-host disease (GVHD)…”
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Antibody response after vaccination against SARS-CoV-2 in adults with hematological malignancies: a systematic review and meta-analysis by Gagelmann, Nico, Passamonti, Francesco, Wolschke, Christine, Massoud, Radwan, Niederwieser, Christian, Adjallé, Raissa, Mora, Barbara, Ayuk, Francis, Kröger, Nicolaus

“…Vaccines against SARS-CoV-2 have shown remarkable efficacy and thus constitute an important preventive option against coronavirus disease 2019 (COVID-19),…”
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Impact of high-risk disease on the efficacy of chimeric antigen receptor T-cell therapy for multiple myeloma: a meta-analysis of 723 patients by Gagelmann, Nico, Ayuk, Francis A., Klyuchnikov, Evgeny, Wolschke, Christine, Berger, Susanna Carolina, Kröger, Nicolaus

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TKI Maintenance After Stem-Cell Transplantation for FLT3 -ITD Positive Acute Myeloid Leukemia: A Systematic Review and Meta-Analysis by Gagelmann, Nico, Wolschke, Christine, Klyuchnikov, Evgeny, Christopeit, Maximilian, Ayuk, Francis, Kröger, Nicolaus

“…This analysis aimed to systematically review and synthesize the existing evidence regarding the outcome of tyrosine kinase inhibitor (TKI) maintenance therapy…”
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Long-term CD38 saturation by daratumumab interferes with diagnostic myeloma cell detection by Oberle, Anna, Brandt, Anna, Alawi, Malik, Langebrake, Claudia, Janjetovic, Snjezana, Wolschke, Christine, Schütze, Kerstin, Bannas, Peter, Kröger, Nicolaus, Koch-Nolte, Friedrich, Bokemeyer, Carsten, Binder, Mascha

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Molecular monitoring of T-cell kinetics and migration in severe neurotoxicity after real-world CD19-specific chimeric antigen receptor T cell therapy by Berger, Susanna Carolina, Fehse, Boris, Akyüz, Nuray, Geffken, Maria, Wolschke, Christine, Janson, Dietlinde, Gagelmann, Nico, Luther, Marlene, Wichmann, Dominic, Frenzel, Christian, Thayssen, Guenther, Alegiani, Anna, Badbaran, Anita, Zeschke, Silke, Dierlamm, Judith, Kröger, Nicolaus, Ayuk, Francis A

“…CD19-specific chimeric antigen receptor (CD19-CAR) T-cell therapies mediate durable responses in late-stage B-cell malignancies, but can be complicated by a…”
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Autologous-allogeneic versus autologous tandem stem cell transplantation and maintenance therapy with thalidomide for multiple myeloma patients under 60 years of age: a prospective, phase II study by Kröger, Nicolaus, Wulf, Gerald, Hegenbart, Ute, Burchert, Andreas, Stelljes, Matthias, Gagelmann, Nico, Brecht, Arne, Kaufmann, Martin, Müller, Lutz, Ganser, Arnold, Wolf, Dominik, Bethge, Wolfgang, Bornhäuser, Martin, Kiehl, Michael, Wagner, Eva-Maria, Schmid, Christoph, Reinhardt, Hans Christian, Kobbe, Guido, Salwender, Hans, Heinicke, Thomas, Kropff, Martin, Heinzelmann, Marion, Ayuk, Francis, Trümper, Lorenz, Neubauer, Andreas, Völp, Andreas, Kluychnikov, Evgeny, Schönland, Stefan, Wolschke, Christine

“…The role of autologous-allogeneic tandem stem cell transplantation (alloTSCT) followed by maintenance as upfront treatment for multiple myeloma is…”
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Donor Lymphocyte Infusion and Molecular Monitoring for Relapsed Myelofibrosis After Hematopoietic Cell Transplantation by Gagelmann, Nico, Wolschke, Christine, Badbaran, Anita, Janson, Dietlinde, Berger, Carolina, Klyuchnikov, Evgeny, Ayuk, Francis, Fehse, Boris, Kröger, Nicolaus

“…Hematopoietic cell transplantation (HCT) is a curative approach for myelofibrosis patients, but relapse is a major cause of treatment failure. We investigated…”
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Use of ropeginterferon in inducing graft versus myelofibrosis effect in post‐transplant myelofibrosis relapse by Srivastava, Barnali, Wolschke, Christine, Gagelmann, Nico, Badbaran, Anita, Kröger, Nicolaus

“…Key Clinical Message Here, we describe a patient with post‐transplant myelofibrosis with chronic graft‐versus‐host disease (GVHD), who showed successful…”
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Rapid development of cefiderocol resistance in a carbapenem-resistant Pseudomonas aeruginosa isolate associated with mutations in the pyoverdine biosynthesis pathway by Brakert, Luise, Berneking, Laura, Both, Anna, Berinson, Benjamin, Huang, Jiabin, Aepfelbacher, Martin, Wolschke, Christine, Wichmann, Dominic, Rohde, Holger

“…Here we report the in vivo development of cefiderocol resistance within 11 days after therapy initiation in a critically ill patient with bloodstream…”
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Major central nervous system complications after allogeneic stem cell transplantation: A large retrospective study on 888 consecutive adult patients by Mannina, Daniele, Berneking, Laura, Both, Anna, Timm, Wiebke, Urbanowicz, Tatiana, Wolschke, Christine, Ayuketang Ayuk, Francis, Fischer, Nicole, Fiehler, Jens, Grzyska, Ulrich, Rösner, Sabine, Choe, Chi‐Un, Kröger, Nicolaus, Christopeit, Maximilian

“…Objectives Major complications affecting the central nervous system (CNS) present a challenge after allogeneic stem cell transplantation (allo‐SCT). Methods…”
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Antilymphocyte globulin for matched sibling donor transplantation in patients with myelofibrosis by Robin, Marie, Chevret, Sylvie, Koster, Linda, Wolschke, Christine, Yakoub-Agha, Ibrahim, Bourhis, Jean Henri, Chevallier, Patrice, Cornelissen, Jan J, Reményi, Péter, Maertens, Johan, Poiré, Xavier, Craddock, Charles, Socié, Gérard, Itälä-Remes, Maija, Schouten, Harry C, Marchand, Tony, Passweg, Jakob, Blaise, Didier, Damaj, Gandhi, Ozkurt, Zubeyde Nur, Zuckerman, Tsila, Cluzeau, Thomas, Labussière-Wallet, Hélène, Cammenga, Jörg, McLornan, Donal, Chalandon, Yves, Kröger, Nicolaus

“…The use of antihuman T-lymphocyte immunoglobulin in the setting of transplantation from an HLA-matched related donor is still much debated. Acute and chronic…”
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aHSCT is superior to alemtuzumab in maintaining NEDA and improving cognition in multiple sclerosis by Häußler, Vivien, Ufer, Friederike, Pöttgen, Jana, Wolschke, Christine, Friese, Manuel A., Kröger, Nicolaus, Heesen, Christoph, Stellmann, Jan‐Patrick

“…Objective Autologous hematopoietic stem cell transplantation (aHSCT) is increasingly recognized as a potential therapy for patients with highly active multiple…”
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Donor lymphocyte infusions and second transplantation as salvage treatment for relapsed myelofibrosis after reduced-intensity allografting by Klyuchnikov, Evgeny, Holler, Ernst, Bornhäuser, Martin, Kobbe, Guido, Nagler, Arnon, Shimoni, Avichai, Könecke, Christian, Wolschke, Christine, Bacher, Ulrike, Zander, Axel R., Kröger, Nicolaus

“…Summary Thirty myelofibrosis patients (21 males, nine females) with relapse (n = 27) or graft‐rejection (n = 3) after dose‐reduced allografting underwent a…”
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Ruxolitinib for Myelofibrosis Patients Relapsing after Allogeneic Hematopoietic Transplantation by Janson, Dietlinde, Ayuk, Francis A, Wolschke, Christine, Christopeit, Maximilian, Badbaran, Anita, von Pein, Ute-Marie, van Randenborgh, Andre, Kroeger, Nicolaus

“…Introduction The Janus-Activated Kinase (JAK) 1/2 -inhibitor ruxolitinib is approved for the treatment of symptomatic myelofibrosis (MF) regardless of the JAK2…”
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High Molecular and Cytogenetic Risk in Myelofibrosis Does Not Benefit From Higher Intensity Conditioning Before Hematopoietic Cell Transplantation: An International Collaborative Analysis by Gagelmann, Nico, Salit, Rachel B., Schroeder, Thomas, Badbaran, Anita, Rautenberg, Christina, Panagiota, Victoria, Wolschke, Christine, Thol, Felicitas, Cassinat, Bruno, Robin, Marie, Heuser, Michael, Reinhardt, Hans Christian, Scott, Bart L., Kröger, Nicolaus

“…There is no direct evidence to recommend specific conditioning intensities in myelofibrosis undergoing allogeneic hematopoietic cell transplantation,…”
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Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation by Atanackovic, Djordje, Arfsten, Julia, Cao, Yanran, Gnjatic, Sacha, Schnieders, Frank, Bartels, Katrin, Schilling, Georgia, Faltz, Christiane, Wolschke, Christine, Dierlamm, Judith, Ritter, Gerd, Eiermann, Thomas, Hossfeld, Dieter Kurt, Zander, Axel R., Jungbluth, Achim A., Old, Lloyd J., Bokemeyer, Carsten, Kröger, Nicolaus

“…Immunotherapies using cancer-testis (CT) antigens as targets represent a potentially useful treatment in patients with multiple myeloma (MM) who commonly show…”
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Sorafenib As Maintenance Therapy Post Allogeneic Stem Cell Transplantation for FLT3-ITD Positive AML: Results from the Randomized, Double-Blind, Placebo-Controlled Multicentre Sormain Trial by Burchert, Andreas, Bug, Gesine, Finke, Jürgen, Stelljes, Matthias, Rollig, Christoph, Wäsch, Ralph, Bornhäuser, Martin, Berg, Tobias, Lang, Fabian, Ehninger, Gerhard, Serve, Hubert, Zeiser, Robert, Wagner, Eva-Maria, Kroeger, Nicolaus, Wolschke, Christine, Schleuning, Michael, Elmaagacli, Ahmet, Götze, Katharina S., Schmid, Christoph, Jost, Edgar, Wolf, Dominik, Böhm, Alexandra, Thiede, Christian, Haferlach, Torsten, Bethge, Wolfgang, Harnisch, Susanne, Wittenberg, Michael, Rospleszcz, Susanne, Neubauer, Andreas, Brugger, Markus, Strauch, Konstantin, Schade-Brittinger, Carmen, Metzelder, Stephan K

“…▪ Introduction: Most patients with FLT3-ITD-positive AML, who relapse after allogenic stem cell transplantation (allo-SCT) die from their disease. Whether…”
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Myeloablative and Reduced-Intensity Conditioned Allogeneic Hematopoietic Stem Cell Transplantation in Myelofibrosis: A Retrospective Study by the Chronic Malignancies Working Party of the European Society for Blood and Marrow Transplantation by McLornan, Donal, Szydlo, Richard, Koster, Linda, Chalandon, Yves, Robin, Marie, Wolschke, Christine, Beelen, Dietrich, Socié, Gerard, Bornhäuser, Martin, Angelucci, Emanuele, Niederwieser, Dietger, Gerbitz, Arnim, Finke, Jürgen, Vitek, Antonin, Itälä-Remes, Maija, Radujkovic, Aleksandar, Kanz, Lothar, Potter, Victoria, Chevallier, Patrice, Stelljes, Matthias, Petersen, Eefke, Robinson, Stephen, Poiré, Xavier, Klyuchnikov, Evgeny, Hernández-Boluda, Juan Carlos, Czerw, Tomasz, Hayden, Patrick, Kröger, Nicolaus, Yakoub-Agha, Ibrahim

“…•In this largest cohort of myelofibrosis transplants analyzed to date, no significant difference in 5-year probabilities of overall survival (OS) was noted…”
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Comparison of Different Rabbit Anti-Thymocyte Globulin Formulations in Allogeneic Stem Cell Transplantation: Systematic Literature Review and Network Meta-Analysis by Gagelmann, Nico, Ayuk, Francis, Wolschke, Christine, Kröger, Nicolaus

“…•Different brands have different effects.•No increased risk of relapse. Since 2000, various phase III randomized controlled trials (RCTs) have investigated the…”
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