Search Results - "Christina A. Herrick"

TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis by Liu, Boyi, Escalera, Jasmine, Balakrishna, Shrilatha, Fan, Lu, Caceres, Ana I., Robinson, Eve, Sui, Aiwei, McKay, M. Craig, McAlexander, M. Allen, Herrick, Christina A., Jordt, Sven E.

“…Allergic contact dermatitis is a common skin disease associated with inflammation and persistent pruritus. Transient receptor potential (TRP) ion channels in…”
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TLR4 Signaling in Stromal Cells Is Critical for the Initiation of Allergic Th2 Responses to Inhaled Antigen by Tan, Anna M, Chen, Hui-Chen, Pochard, Pierre, Eisenbarth, Stephanie C, Herrick, Christina A, Bottomly, H. Kim

“…Allergic asthma is an inflammatory lung disease driven by Th2. We have shown that both Th1 and Th2 sensitization to inhaled OVA depend on the presence and…”
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Skin Exposure to Isocyanates: Reasons for Concern by Dhimiter Bello, Christina A. Herrick, Smith, Thomas J., Woskie, Susan R., Streicher, Robert P., Mark R. Cullen, Youcheng Liu, Redlich, Carrie A.

“…Objective: Isocyanates (di- and poly-), important chemicals used worldwide to produce polyurethane products, are a leading cause of occupational asthma…”
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Role of Macrophage Migration Inhibitory Factor in the Th2 Immune Response to Epicutaneous Sensitization by Das, Rituparna, Moss, Jeremy E., Robinson, Eve, Roberts, Scott, Levy, Rebecca, Mizue, Yuka, Leng, Lin, McDonald, Courtney, Tigelaar, Robert E., Herrick, Christina A., Bucala, Richard

“…We examined the role of macrophage migration inhibitory factor (MIF) in the generation of the Th2 response using MIF-deficient mice in a model of epicutaneous…”
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A novel mouse model of diisocyanate-induced asthma showing allergic-type inflammation in the lung after inhaled antigen challenge by Herrick, Christina A., Xu, Lan, Wisnewski, Adam V., Das, Jyoti, Redlich, Carrie A., Bottomly, Kim

“…Background: Exposure to diisocyanates, a group of highly reactive, low-molecular-weight compounds, is a major cause of occupational asthma. In contrast to…”
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Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses by Wisnewski, Adam V, Xu, Lan, Robinson, Eve, Liu, Jian, Redlich, Carrie A, Herrick, Christina A

“…Methylene diphenyl diisocyanate (MDI), a reactive chemical used for commercial polyurethane production, is a well-recognized cause of occupational asthma. The…”
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To respond or not to respond: T cells in allergic asthma by Herrick, Christina A, Bottomly, Kim

“…The incidence of allergic asthma has almost doubled in the past two decades. Numerous epidemiological studies have linked the recent surge in atopic disease…”
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Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen by Eisenbarth, Stephanie C, Piggott, Damani A, Huleatt, James W, Visintin, Irene, Herrick, Christina A, Bottomly, Kim

“…Allergic asthma is an inflammatory lung disease initiated and directed by T helper cells type 2 (Th2). The mechanism involved in generation of Th2 responses to…”
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EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation by Dokmeci, Elif, Xu, Lan, Robinson, Eve, Golubets, Kseniya, Bottomly, Kim, Herrick, Christina A

“…Despite extensive investigation of the signals required for development of T helper type 1 (Th1) and type 2 (Th2) immune responses, the mechanisms involved are…”
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MyD88-dependent induction of allergic Th2 responses to intranasal antigen by Piggott, Damani A, Eisenbarth, Stephanie C, Xu, Lan, Constant, Stephanie L, Huleatt, James W, Herrick, Christina A, Bottomly, Kim

“…MyD88 is a common Toll-like receptor (TLR) adaptor molecule found to be essential for induction of adaptive Th1 immunity. Conversely, innate control of…”
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Lung/skin connections in occupational lung disease by Redlich, Carrie A, Herrick, Christina A

“…PURPOSE OF REVIEWExposure to occupational and environmental agents can cause a spectrum of lung diseases that are predominantly immune-mediated. Research and…”
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The immune system and atopic dermatitis by Dokmeci, Elif, Herrick, Christina A

“…Atopic dermatitis (AD) is a chronic inflammatory skin disease with a complex pathogenesis. It is clinically well-defined and represents one manifestation of…”
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Resident lung antigen-presenting cells have the capacity to promote Th2 T cell differentiation in situ by Constant, Stephanie L, Brogdon, Jennifer L, Piggott, Damani A, Herrick, Christina A, Visintin, Irene, Ruddle, Nancy H, Bottomly, Kim

“…Antigen exposure via airway epithelia is often associated with a failure to prime or with the preferential priming of Th2 cells. We previously reported that…”
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IL-4-Dependent Th2 Collateral Priming to Inhaled Antigens Independent of Toll-Like Receptor 4 and Myeloid Differentiation Factor 88 by Eisenbarth, Stephanie C, Zhadkevich, Alex, Ranney, Patricia, Herrick, Christina A, Bottomly, Kim

“…Allergic asthma is an inflammatory lung disease thought to be initiated and directed by type 2 helper T cells responding to environmental Ags. The mechanisms…”
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IL-13 Is Necessary, Not Simply Sufficient, for Epicutaneously Induced Th2 Responses to Soluble Protein Antigen by Herrick, Christina A, Xu, Lan, McKenzie, Andrew N. J, Tigelaar, Robert E, Bottomly, Kim

“…Th2 responses are clearly involved in the pathogenesis of atopic disease. Thus, understanding the factors responsible for Th2 sensitization at sites of…”
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Differential roles for CD4 and CD8 T cells after diisocyanate sensitization: Genetic control of TH2-induced lung inflammation by Herrick, Christina A., Das, Jyoti, Xu, Lan, Wisnewski, Adam V., Redlich, Carrie A., Bottomly, Kim

“…Background: Exposure to diisocyanates is a major cause of occupational asthma. We previously developed a novel mouse model of diisocyanate-induced asthma…”
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Human γ/δ T-cell proliferation and IFN-γ production induced by hexamethylene diisocyanate by Wisnewski, Adam V, Herrick, Christina A, Liu, Qing, Chen, Liang, Bottomly, Kim, Redlich, Carrie A

“…The human immune response to isocyanate, a leading cause of occupational asthma, remains incompletely characterized, including the cell types involved and the…”
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Neuropeptide-mediated regulation of hapten-specific IgE responses in mice. I. Substance P-mediated isotype-specific suppression of BPO-specific IgE antibody-forming cell responses induced in vivo and in vitro by Carucci, J A, Auci, D L, Herrick, C A, Durkin, H G

“…The ability of substance P (SP) to regulate peak benzyl-penicilloyl (BPO)-specific IgE antibody-forming cell (AFC) responses in vivo and the ability of SP and…”
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EBI3 deficiency leads to diminished T helper type 1 and increased T helper type 2 mediated airway inflammation: EBI3 deficiency leads to diminished Th1, increased Th2 by Dokmeci, Elif, Xu, Lan, Robinson, Eve, Golubets, Kseniya, Bottomly, Kim, Herrick, Christina A.

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Th2 responses induced by epicutaneous or inhalational protein exposure are differentially dependent on IL-4 by Herrick, C A, MacLeod, H, Glusac, E, Tigelaar, R E, Bottomly, K

“…Atopic individuals are predisposed to mounting vigorous Th2-type immune responses to environmental allergens. To determine the factors responsible, animal…”
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