Search Results - "Christie, Shaun M."
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V(D)J Recombination: Recent Insights in Formation of the Recombinase Complex and Recruitment of DNA Repair Machinery
Published in Frontiers in cell and developmental biology (29-04-2022)“…V(D)J recombination is an essential mechanism of the adaptive immune system, producing a diverse set of antigen receptors in developing lymphocytes via…”
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Interactions between semaphorins and plexin–neuropilin receptor complexes in the membranes of live cells
Published in The Journal of biological chemistry (01-08-2021)“…Signaling of semaphorin ligands via their plexin–neuropilin receptors is involved in tissue patterning in the developing embryo. These proteins play roles in…”
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Single-virus tracking reveals variant SARS-CoV-2 spike proteins induce ACE2-independent membrane interactions
Published in Science advances (09-12-2022)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) became a global health crisis after its emergence in 2019. Replication of the virus is initiated…”
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Covalently Immobilizing Interferon‑γ Drives Filopodia Production through Specific Receptor–Ligand Interactions Independently of Canonical Downstream Signaling
Published in Bioconjugate chemistry (20-05-2020)“…Immobilizing a signaling protein to guide cell behavior has been employed in a wide variety of studies. This approach draws inspiration from biology, where…”
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Interactions between the Transmembrane Domains of Plexin, Semaphorin, and Neuropilin
Published in Biophysical journal (02-02-2018)Get full text
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Elucidation of Membrane Protein Interactions Under Native and Ligand Stimulated Conditions Using Fluorescence Correlation Spectroscopy
Published 01-01-2020“…The receptors embedded in cell membranes are essential for signaling in response to various stimuli or communicating with neighboring cells. In order to target…”
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Dissertation