Search Results - "Christie, Christine K."

Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice by Halim, Danny, Wilson, Michael P., Oliver, Daniel, Brosens, Erwin, Verheij, Joke B. G. M., Han, Yu, Nanda, Vivek, Lyu, Qing, Doukas, Michael, Stoop, Hans, Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Slivano, Orazio J., Burns, Alan J., Christie, Christine K., de Mesy Bentley, Karen L., Brooks, Alice S., Tibboel, Dick, Xu, Suowen, Jin, Zheng Gen, Djuwantono, Tono, Yan, Wei, Alves, Maria M., Hofstra, Robert M. W., Miano, Joseph M.

“…Megacystis microcolon intestinal hypoperistalsis syndrome (MMIHS) is a congenital visceral myopathy characterized by severe dilation of the urinary bladder and…”
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CRISPR-Cas9 Genome Editing of a Single Regulatory Element Nearly Abolishes Target Gene Expression in Mice—Brief Report by Han, Yu, Slivano, Orazio J, Christie, Christine K, Cheng, Albert W, Miano, Joseph M

“…OBJECTIVE—To ascertain the importance of a single regulatory element in the control of Cnn1 expression using CRISPR/Cas9 (clustered regularly interspaced short…”
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CRISPR-Cas9–Mediated Epitope Tagging Provides Accurate and Versatile Assessment of Myocardin—Brief Report by Lyu, Qing, Dhagia, Vidhi, Han, Yu, Guo, Bing, Wines-Samuelson, Mary E, Christie, Christine K, Yin, Qiangzong, Slivano, Orazio J, Herring, Paul, Long, Xiaochun, Gupte, Sachin A, Miano, Joseph M

“…OBJECTIVE—Unreliable antibodies often hinder the accurate detection of an endogenous protein, and this is particularly true for the cardiac and smooth muscle…”
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SENCR stabilizes vascular endothelial cell adherens junctions through interaction with CKAP4 by Lyu, Qing, Xu, Suowen, Lyu, Yuyan, Choi, Mihyun, Christie, Christine K., Slivano, Orazio J., Rahman, Arshad, Jin, Zheng-Gen, Long, Xiaochun, Xu, Yawei, Miano, Joseph M.

“…SENCR is a human-specific, vascular cell-enriched long-noncoding RNA (lncRNA) that regulates vascular smooth muscle cell and endothelial cell (EC) phenotypes…”
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Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function by Guo, Bing, Lyu, Qing, Slivano, Orazio J, Dirkx, Ronald, Christie, Christine K, Czyzyk, Jan, Hezel, Aram F, Gharavi, Ali G, Small, Eric M, Miano, Joseph M

“…Podocytes contain an intricate actin cytoskeleton that is essential for the specialized function of this cell type in renal filtration. Serum response factor…”
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G-Protein–Coupled Receptor-2–Interacting Protein-1 Is Required for Endothelial Cell Directional Migration and Tumor Angiogenesis via Cortactin-Dependent Lamellipodia Formation by Majumder, Syamantak, Sowden, Mark P, Gerber, Scott A, Thomas, Tamlyn, Christie, Christine K, Mohan, Amy, Yin, Guoyong, Lord, Edith M, Berk, Bradford C, Pang, Jinjiang

“…OBJECTIVE—Recent evidence suggests G-protein–coupled receptor-2–interacting protein-1 (GIT1) overexpression in several human metastatic tumors, including…”
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CRISPR-Cas9 Mediated Epitope Tagging Provides Accurate and Versatile Assessment of Myocardin by Lyu, Qing, Dhagia, Vidhi, Han, Yu, Guo, Bing, Wines-Samuelson, Mary E, Christie, Christine K, Yin, Qiangzong, Slivano, Orazio J, Herring, Paul, Long, Xiaochun, Gupte, Sachin A, Miano, Joseph M

“…OBJECTIVE—Unreliable antibodies often hinder the accurate detection of an endogenous protein, and this is particularly true for the cardiac and smooth muscle…”
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CRISPR-Cas9 Genome Editing of a Single Regulatory Element Nearly Abolishes Target Gene Expression in Mice by Han, Yu, Slivano, Orazio J., Christie, Christine K., Cheng, Albert W., Miano, Joseph M.

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