Search Results - "Christie, C"
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MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer
Published in Cold Spring Harbor perspectives in medicine (01-11-2016)“…During development, precise spatiotemporal patterns of gene expression are coordinately controlled by cis-regulatory modules known as enhancers. Their crucial…”
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Author Correction: Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation
Published in Nature reviews. Immunology (01-04-2024)Get full text
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Using BCG vaccination to protect against COVID-19: when reality fails to meet expectation
Published in Nature reviews. Immunology (01-02-2024)“…While anticipating the development of a COVID-19-specific vaccine, several randomized controlled trials (RCTs) explored the potential of BCG vaccination to…”
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Uncoupling histone H3K4 trimethylation from developmental gene expression via an equilibrium of COMPASS, Polycomb and DNA methylation
Published in Nature genetics (01-06-2020)“…The COMPASS protein family catalyzes histone H3 Lys 4 (H3K4) methylation and its members are essential for regulating gene expression. MLL2/COMPASS methylates…”
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Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability
Published in Nature genetics (01-11-2017)“…Ali Shilatifard and colleagues generate Drosophila lines expressing catalytically deficient Trr, which normally deposits H3K4me1 at enhancers. Trr mutants…”
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Wonder as a tool to engage preservice elementary teachers in science learning and teaching
Published in Science education (Salem, Mass.) (01-11-2017)“…This exploratory project considers the use of wonder as a pedagogical tool with preservice elementary teachers (PSETs). An ongoing vexation facing science…”
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A cytoplasmic COMPASS is necessary for cell survival and triple-negative breast cancer pathogenesis by regulating metabolism
Published in Genes & development (15-10-2017)“…Mutations and translocations within the COMPASS (complex of proteins associated with Set1) family of histone lysine methyltransferases are associated with a…”
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Histone H3K4 methylation-dependent and -independent functions of Set1A/COMPASS in embryonic stem cell self-renewal and differentiation
Published in Genes & development (01-09-2017)“…Of the six members of the COMPASS (complex of proteins associated with Set1) family of histone H3 Lys4 (H3K4) methyltransferases identified in mammals, Set1A…”
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Interpreting the Results of Trials of BCG Vaccination for Protection Against COVID-19
Published in The Journal of infectious diseases (15-11-2023)“…Abstract BCG vaccination has beneficial off-target (“nonspecific”) effects on nonmycobacterial infections. On this premise, trials set out to investigate…”
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Neighborhood Disadvantage and Poor Health: The Consequences of Race, Gender, and Age among Young Adults
Published in International journal of environmental research and public health (01-07-2022)“…The objective of this study is to examine the relationship between neighborhood disadvantage and poor self-rated health for a nationally representative sample…”
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The prevalence of self-reported mental illness among those imprisoned in New South Wales across three health surveys, from 2001 to 2015
Published in Australian and New Zealand journal of psychiatry (01-04-2023)“…Objective: The prevalence of mental illness among those in prison is much higher than in the community; however, very few studies have examined whether rates…”
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Postdischarge interventions for children hospitalized with severe acute malnutrition: a systematic review and meta-analysis
Published in The American journal of clinical nutrition (01-03-2021)“…Children hospitalized with severe acute malnutrition (SAM) have poor long-term outcomes following discharge, with high rates of mortality, morbidity, and…”
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MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer
Published in Cold Spring Harbor perspectives in medicine (01-11-2016)Get full text
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Hybrid Perovskites with Larger Organic Cations Reveal Autocatalytic Degradation Kinetics and Increased Stability under Light
Published in Inorganic chemistry (08-09-2020)“…Hybrid organic–inorganic perovskites have shown incredible promise as active materials for photovoltaic devices, but their instability to light remains a…”
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The effects of sustained virological response to direct‐acting anti‐viral therapy on the risk of extrahepatic manifestations of hepatitis C infection
Published in Alimentary pharmacology & therapeutics (01-06-2019)“…Summary Background Direct‐acting anti‐viral (DAA) therapy may have a beneficial role in extrahepatic manifestations of hepatitis C virus (HCV) infection…”
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JNK activation and translocation to mitochondria mediates mitochondrial dysfunction and cell death induced by VDAC opening and sorafenib in hepatocarcinoma cells
Published in Biochemical pharmacology (01-01-2020)“…[Display omitted] The multikinase inhibitor sorafenib, and opening of voltage dependent anion channels (VDAC) by the erastin-like compound X1 promotes…”
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SET1A/COMPASS and shadow enhancers in the regulation of homeotic gene expression
Published in Genes & development (15-04-2017)“…The homeotic (Hox) genes are highly conserved in metazoans, where they are required for various processes in development, and misregulation of their expression…”
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A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation
Published in Genes & development (01-10-2017)“…Histone H3 Lys4 (H3K4) methylation is a chromatin feature enriched at gene -regulatory sequences such as promoters and enhancers. Here we identify an…”
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The impact of sleep, physical activity and sedentary behaviour on symptoms of depression and anxiety before and during the COVID-19 pandemic in a sample of South African participants
Published in Scientific reports (15-12-2021)“…During lockdowns associated with the COVID-19 pandemic, individuals have experienced poor sleep quality and sleep regularity, changes in lifestyle behaviours,…”
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Autonomic specificity of basic emotions: Evidence from pattern classification and cluster analysis
Published in Biological psychology (01-07-2010)“…Autonomic nervous system (ANS) specificity of emotion remains controversial in contemporary emotion research, and has received mixed support over decades of…”
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