Search Results - "Christiansen, Freddy B"

Environment-sensitive epigenetics and the heritability of complex diseases by Furrow, Robert E, Christiansen, Freddy B, Feldman, Marcus W

“…Genome-wide association studies have thus far failed to explain the observed heritability of complex human diseases. This is referred to as the "missing…”
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Selection at Work in Self-Incompatible Arabidopsis lyrata. II. Spatial Distribution of S Haplotypes in Iceland by Schierup, Mikkel H, Bechsgaard, Jesper S, Christiansen, Freddy B

“…We survey the distribution of haplotypes at the self-incompatibility (SI) locus of Arabidopsis lyrata (Brassicaceae) at 12 locations spread over the species'…”
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Selection at Work in Self-Incompatible Arabidopsis lyrata: Mating Patterns in a Natural Population by Schierup, Mikkel H, Bechsgaard, Jesper S, Nielsen, Lene H, Christiansen, Freddy B

“…Identification and characterization of the self-incompatibility genes in Brassicaceae species now allow typing of self-incompatibility haplotypes in natural…”
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Influenza drift and epidemic size: the race between generating and escaping immunity by Boni, Maciej F., Gog, Julia R., Andreasen, Viggo, Christiansen, Freddy B.

“…Influenza in humans is characterised by strongly annual dynamics and antigenic evolution leading to partial escape from prior host immunity. The variability of…”
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Mate availability and fecundity selection in multi-allelic self-incompatibility systems in plants by Vekemans, X, Schierup, M.H, Christiansen, F.B

“…We investigate mate availability in different models of multiallelic self-incompatibility systems in mutation-selection-drift balance in finite populations…”
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Slow Coevolution of a Viral Pathogen and Its Diploid Host by Acrivos, Andreas, Christiansen, Freddy B.

“…We study a population exposed to a lethal infectious disease. Host response is carried at one locus with two alleles while the pathogen occurs in two variants…”
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POPULATION GENETIC PERSPECTIVES ON THE EVOLUTION OF RECOMBINATION by Feldman, Marcus W, Otto, Sarah P, Christiansen, Freddy B

“…Optimality arguments and modifier theory are reviewed as paradigms for the study of the evolution of recombination. Optimality criteria (such as maximization…”
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Evolutionary dynamics of sporophytic self-incompatibility alleles in plants by Schierup, M.H. (University of Aarhus, Aarhus, Denmark.), Vekemans, X, Christiansen, F.B

“…The stationary frequency distribution and allelic dynamics in finite populations are analyzed through stochastic simulations in three models of single-locus,…”
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Allelic genealogies in sporophytic self-incompatibility systems in plants by Schierup, M.H. (University of Aarhus, Denmark.), Vekemans, X, Christiansen, F.B

“…Expectations for the time scale and structure of allelic genealogies in finite populations are formed under three models of sporophytic self-incompatibility…”
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Evolution of Recombination Among Multiple Selected Loci: A Generalized Reduction Principle by Zhivotovsky, Lev A., Feldman, Marcus W., Christiansen, Freddy B.

“…Conditions for invasion by a new allele that controls the recombination pattern among an arbitrary number of genes under viability selection are studied. The…”
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Gene-culture co-evolution: teaching, learning, and correlations between relatives by Feldman, Marcus W., Christiansen, Freddy B., Otto, Sarah P.

“…Heritability, the fraction of phenotypic variance attributable to the action of genes, is usually derived from a linear statistical partition of variance. In…”
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evolution of self-fertilization in plants: a population genetic model by Holsinger, K.E, Feldman, M.W, Christiansen, F.B

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Evolution of Recombination in a Constant Environment by Feldman, Marcus W., Christiansen, Freddy B., Brooks, Lisa D.

“…The theory of evolution at a selectively neutral locus that controls the recombination between two major loci that are under selection is studied. If the major…”
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Population Genetic Theory of the Cost of Inbreeding by Feldman, Marcus, Christiansen, Freddy B.

“…Single gene models for the evolution of rates of selfing and sib mating in the presence of an inbreeding depression of fitness are treated. In models in which…”
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ON SOME MODELS OF FERTILITY SELECTION by Feldman, Marcus W, Christiansen, Freddy B, Liberman, Uri

“…Additive, multiplicative and symmetric models of fertility controlled by one diallelic gene are studied. For the completely symmetric fertility system a…”
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SELECTION IN COMPLEX GENETIC SYSTEMS III. AN EFFECT OF ALLELE MULTIPLICITY WITH TWO LOCI by Feldman, Marcus W, Lewontin, Richard C, Franklin, Ian R, Christiansen, Freddy B

“…A two-locus model with three alleles at one locus and two at the other is studied. The viability system is such that all double heterozygotes have fitness…”
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A codon-based model designed to describe lentiviral evolution by Pedersen, A K, Wiuf, C, Christiansen, F B

“…A codon-based model designed to describe lentiviral evolution is developed. The model incorporates unequal base compositions in the three codon positions and…”
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Waiting with and without Recombination: The Time to Production of a Double Mutant by Christiansen, Freddy B., Otto, Sarah P., Bergman, Aviv, Feldman, Marcus W.

“…R. A. Fisher and H. J. Muller argued in the 1930s that a major evolutionary advantage of recombination is that it allows favorable mutations to be combined…”
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Mate Availability and Fecundity Selection in Multi-Allelic Self- Incompatibility Systems in Plants by Vekemans, Xavier, Schierup, Mikkel H., Christiansen, Freddy B.

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Density-dependent selection by Christiansen, Freddy B.

“…IntroductionThe classical studies of the interplay between natural selection on a character and Mendelian inheritance of variant traits employed simple models,…”
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