Search Results - "Christian Larroque"
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1
Chemical Characterization and Biological Activity of the Essential Oil from Araucaria brasiliensis Collected in Ecuador
Published in Molecules (Basel, Switzerland) (13-06-2022)“…The purpose of this study was to determine the chemical composition, physical properties, enantiomeric composition and cholinesterase inhibitory activity of…”
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2
Exploring Southern Ecuador's Traditional Medicine: Biological Screening of Plant Extracts and Metabolites
Published in Plants (Basel) (01-05-2024)“…Ecuador stands as a nation inheriting a profound ancestral legacy in the utilization of medicinal plants, reflective of the rich biodiversity embraced by…”
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3
A Novel Chemical Profile of a Selective In Vitro Cholinergic Essential Oil from Clinopodium taxifolium (Kunth) Govaerts (Lamiaceae), a Native Andean Species of Ecuador
Published in Molecules (Basel, Switzerland) (23-12-2020)“…A novel chemical profile essential oil, distilled from the aerial parts of (Kunth) Govaerts (Lamiaceae), was analysed by Gas Chromatography-Mass Spectrometry…”
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4
Proteasome 19S RP and translation preinitiation complexes are secreted within exosomes upon serum starvation
Published in Traffic (Copenhagen, Denmark) (01-07-2019)“…The aim of our study was to investigate the impact of macroautophagy on exosome secretion. Exosomes are small membrane vesicles released in the extracellular…”
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Chemical Composition and Anticholinesterase Activity of the Essential Oil of Leaves and Flowers from the Ecuadorian Plant Lepechinia paniculata (Kunth) Epling
Published in Molecules (Basel, Switzerland) (27-05-2021)“…This work aimed to study the chemical composition, cholinesterase inhibitory activity, and enantiomeric analysis of the essential oil from the aerial parts…”
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6
Nascent DNA Proteomics Reveals a Chromatin Remodeler Required for Topoisomerase I Loading at Replication Forks
Published in Cell reports (Cambridge) (12-04-2016)“…During transcription and DNA replication, the DNA template is overwound ahead of RNA and DNA polymerases and relaxed by DNA topoisomerases. Inhibitors of…”
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Targeting the splicing isoforms of spleen tyrosine kinase affects the viability of colorectal cancer cells
Published in PloS one (14-09-2022)“…Spleen tyrosine kinase (Syk) expression have been both positively and negatively associated with tumorigenesis. Our goal was to evaluate the contribution of…”
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Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity
Published in PloS one (10-08-2017)“…Displaying a strong antiproliferative activity on a wide variety of cancer cells, EAPB0203 and EAPB0503 belong to the imidazo[1,2-a]quinoxalines family of…”
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Phytochemical and ethnomedicinal study of Huperzia species used in the traditional medicine of Saraguros in Southern Ecuador; AChE and MAO inhibitory activity
Published in Journal of ethnopharmacology (04-12-2016)“…This study concerns seven Huperzia species (Lycopodiaceae), namely H. brevifolia, H. columnaris, H. compacta, H. crassa, H. espinosana, H. tetragona, H…”
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10
Matrix-assisted laser desorption/ionization imaging mass spectrometry of oxaliplatin derivatives in heated intraoperative chemotherapy (HIPEC)-like treated rat kidney
Published in Rapid communications in mass spectrometry (01-02-2010)“…Oxaliplatin [1,2‐diaminocyclohexane (dach)‐Pt complex] is a platinum anticancer drug which is mainly used in the treatment of advanced colorectal cancer,…”
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11
Selective BuChE Inhibitory Activity, Chemical Composition, and Enantiomeric Content of the Essential Oil from Salvia leucantha Cav. Collected in Ecuador
Published in Plants (Basel) (09-06-2021)“…The essential oil (EO) of Salvia leucantha Cav. was isolated by steam distillation of the aerial parts collected in the South of Ecuador. Its physical…”
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Constituents, Enantiomeric Content, and ChE Inhibitory Activity of the Essential Oil from Hypericum laricifolium Juss. Aerial Parts Collected in Ecuador
Published in Plants (Basel) (02-11-2022)“…The physical properties, chemical composition, enantiomer distribution, and cholinesterase (ChE) inhibitory activity were determined for a steam-distilled…”
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13
Acorenone B: AChE and BChE Inhibitor as a Major Compound of the Essential Oil Distilled from the Ecuadorian Species Niphogeton dissecta (Benth.) J.F. Macbr
Published in Pharmaceuticals (Basel, Switzerland) (31-10-2017)“…This study investigated the chemical composition, physical proprieties, biological activity, and enantiomeric analysis of the essential oil from the aerial…”
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14
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells
Published in Molecular cancer (25-01-2008)“…Colorectal cancer (CRC) is one of the most common causes of cancer death throughout the world. In this work our aim was to study the role of the phosphoserine…”
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15
Distribution of de novo Donor-Specific Antibody Subclasses Quantified by Mass Spectrometry: High IgG3 Proportion Is Associated With Antibody-Mediated Rejection Occurrence and Severity
Published in Frontiers in immunology (02-06-2020)“…Donor-specific antibodies (DSAs) are the main risk factor for antibody-mediated rejection (ABMR) and graft loss but could have variable pathogenicity according…”
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Constituents and Selective BuChE Inhibitory Activity of the Essential Oil from Hypericum aciculare Kunth
Published in Plants (Basel) (12-07-2023)“…A potential source of new inhibitors of cholinesterase enzymes are certain compounds of natural plant origin; therefore, in the study described herein we have…”
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17
Complementarity of MALDI and LA ICP mass spectrometry for platinum anticancer imaging in human tumor
Published in Metallomics (01-01-2014)“…The follow-up of the Heated Intraoperative Chemotherapy (HIPEC) of peritoneal carcinomatosis would benefit from the monitoring of the penetration, distribution…”
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18
Specific in vivo labeling of tyrosinated α-tubulin and measurement of microtubule dynamics using a GFP tagged, cytoplasmically expressed recombinant antibody
Published in PloS one (28-03-2013)“…GFP-tagged proteins are used extensively as biosensors for protein localization and function, but the GFP moiety can interfere with protein properties. An…”
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Chemical Composition, Enantiomeric Distribution, and Sensory Evaluation of the Essential Oils Distilled from the Ecuadorian Species Myrcianthes myrsinoides (Kunth) Grifo and Myrcia mollis (Kunth) DC. (Myrtaceae)
Published in Plants (Basel) (15-11-2019)“…The essential oils of and , belonging to the Myrtaceae family, were obtained by steam distillation. They were analyzed by gas chromatography-mass spectrometry…”
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Chemical, Enantioselective, and Sensory Analysis of a Cholinesterase Inhibitor Essential Oil from Coreopsis triloba S.F. Blake (Asteraceae)
Published in Plants (Basel) (25-10-2019)“…The fresh leaves of S.F. Blake, collected at Cerro Villonaco in Loja, Ecuador, were investigated with respect to their essential oil (EO). The chemical…”
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