Search Results - "Christian Burri"

Sleeping Sickness at the Crossroads by Burri, Christian

“…Human African trypanosomiasis (HAT; sleeping sickness) is a disease with truly historic dimensions [...]…”
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Human African trypanosomiasis by Brun, Reto, Prof, Blum, Johannes, MD, Chappuis, Francois, MD, Burri, Christian, PhD

“…Summary Human African trypanosomiasis (sleeping sickness) occurs in sub-Saharan Africa. It is caused by the protozoan parasite Trypanosoma brucei , transmitted…”
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Strategies and interventions to strengthen pharmacovigilance systems in low-income and middle-income countries: a scoping review by Menang, Olga, Kuemmerle, Andrea, Maigetter, Karen, Burri, Christian

“…Objectives The slow progress of pharmacovigilance (PV) in low-income and middle-income countries (LMIC) raises questions about core challenges on the growth of…”
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"You can save time if…"-A qualitative study on internal factors slowing down clinical trials in Sub-Saharan Africa by Vischer, Nerina, Pfeiffer, Constanze, Limacher, Manuela, Burri, Christian

“…The costs, complexity, legal requirements and number of amendments associated with clinical trials are rising constantly, which negatively affects the…”
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Fexinidazole for Human African Trypanosomiasis, the Fruit of a Successful Public-Private Partnership by Bernhard, Sonja, Kaiser, Marcel, Burri, Christian, Mäser, Pascal

“…After 100 years of chemotherapy with impractical and toxic drugs, an oral cure for human African trypanosomiasis (HAT) is available: Fexinidazole. In this…”
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Informed consent approaches for clinical trial participation of infants with minor parents in sub-Saharan Africa: A systematic review by De Pretto-Lazarova, Angela, Brancati-Badarau, Domnita Oana, Burri, Christian

“…Regulations are vague regarding the appropriate decision-maker and authority to consent for children of minor parents participating in clinical trials. In…”
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Transparent reporting of recruitment and informed consent approaches in clinical trials recruiting children with minor parents in sub-Saharan Africa: a secondary analysis based on a systematic review by De Pretto-Lazarova, Angela, Brancati-Badarau, Domnita Oana, Burri, Christian

“…Standardised checklists of items to be addressed in clinical study protocols and publications are promoting transparency in research. However, particular…”
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Effectiveness of Nifurtimox Eflornithine Combination Therapy (NECT) in T. b. gambiense second stage sleeping sickness patients in the Democratic Republic of Congo: Report from a field study by Kuemmerle, Andrea, Schmid, Caecilia, Bernhard, Sonja, Kande, Victor, Mutombo, Wilfried, Ilunga, Medard, Lumpungu, Ismael, Mutanda, Sylvain, Nganzobo, Pathou, Tete, Digas Ngolo, Kisala, Mays, Burri, Christian, Blesson, Severine, Valverde Mordt, Olaf

“…Nifurtimox-eflornithine combination therapy (NECT) for the treatment of second stage gambiense human African trypanosomiasis (HAT) was added to the World…”
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Defining clinical trial quality from the perspective of resource-limited settings: A qualitative study based on interviews with investigators, sponsors, and monitors conducting clinical trials in sub-Saharan Africa by De Pretto-Lazarova, Angela, Fuchs, Claudia, van Eeuwijk, Peter, Burri, Christian

“…Increasing clinical trial cost and complexity, as well as a high waste of clinical trial investment over the past decades, have changed the way clinical trial…”
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New drugs for human African trypanosomiasis: A twenty first century success story by Dickie, Emily A, Giordani, Federica, Gould, Matthew K, Mäser, Pascal, Burri, Christian, Mottram, Jeremy C, Rao, Srinivasa P S, Barrett, Michael P

“…The twentieth century ended with human African trypanosomiasis (HAT) epidemics raging across many parts of Africa. Resistance to existing drugs was emerging,…”
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Effectiveness of rectal artesunate as pre-referral treatment for severe malaria in children under 5 years of age: a multi-country observational study by Hetzel, Manuel W, Okitawutshu, Jean, Tshefu, Antoinette, Omoluabi, Elizabeth, Awor, Phyllis, Signorell, Aita, Brunner, Nina C, Kalenga, Jean-Claude, Akano, Babatunde K, Ayodeji, Kazeem, Okon, Charles, Yusuf, Ocheche, Athieno, Proscovia, Kimera, Joseph, Tumukunde, Gloria, Angiro, Irene, Delvento, Giulia, Lee, Tristan T, Lambiris, Mark J, Kwiatkowski, Marek, Cereghetti, Nadja, Visser, Theodoor, Napier, Harriet G, Cohen, Justin M, Buj, Valentina, Burri, Christian, Lengeler, Christian

“…To prevent child deaths from severe malaria, early parenteral treatment is essential. Yet, in remote rural areas, accessing facilities offering parenteral…”
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Key factors predicting suspected severe malaria case management and health outcomes: an operational study in the Democratic Republic of the Congo by Okitawutshu, Jean, Signorell, Aita, Kalenga, Jean-Claude, Mukomena, Eric, Delvento, Giulia, Burri, Christian, Mwaluke, Fatou, Buj, Valentina, Sangare, Moulaye, Luketa, Sylvie, Brunner, Nina, Lee, Tristan, Hetzel, Manuel, Lengeler, Christian, Tshefu, Antoinette

“…Evidence suggests that pre-referral Rectal Artesunate (RAS) can be a life-saving intervention for severe malaria in remote settings in Africa. Recognition of…”
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Assessing caregivers’ perceptions of treatment-seeking for suspected severe malaria in the Democratic Republic of the Congo by Okitawutshu, Jean, Tshefu, Antoinette, Kalenga, Jean-Claude, Delvento, Giulia, Burri, Christian, Hetzel, Manuel W, Lengeler, Christian, Signorell, Aita

“…Abstract Background Malaria remains a major public health issue in the Democratic Republic of the Congo (DRC), accounting for 44% deaths among outpatient…”
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Health worker compliance with severe malaria treatment guidelines in the context of implementing pre-referral rectal artesunate in the Democratic Republic of the Congo, Nigeria, and Uganda: An operational study by Signorell, Aita, Awor, Phyllis, Okitawutshu, Jean, Tshefu, Antoinette, Omoluabi, Elizabeth, Hetzel, Manuel W, Athieno, Proscovia, Kimera, Joseph, Tumukunde, Gloria, Angiro, Irene, Kalenga, Jean-Claude, Akano, Babatunde K, Ayodeji, Kazeem, Okon, Charles, Yusuf, Ocheche, Delvento, Giulia, Lee, Tristan T, Brunner, Nina C, Lambiris, Mark J, Okuma, James, Cereghetti, Nadja, Buj, Valentina, Visser, Theodoor, Napier, Harriet G, Lengeler, Christian, Burri, Christian

“…For a full treatment course of severe malaria, community-administered pre-referral rectal artesunate (RAS) should be completed by post-referral treatment…”
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Methodological approaches for conducting follow-up research with clinical trial participants: a scoping review and expert interviews by Signorell, Aita, Saric, Jasmina, Appenzeller-Herzog, Christian, Ewald, Hannah, Burri, Christian, Goetz, Martin, Gerold, Jana

“…Evidence-based establishment and implementation of best principles, laws and ordinances that regulate clinical research depend on the consultation and…”
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Pre-referral rectal artesunate is no "magic bullet" in weak health systems by Hetzel, Manuel W, Okitawutshu, Jean, Tshefu, Antoinette, Omoluabi, Elizabeth, Awor, Phyllis, Signorell, Aita, Kwiatkowski, Marek, Lambiris, Mark J, Visser, Theodoor, Cohen, Justin M, Buj, Valentina, Burri, Christian, Lengeler, Christian

“…Severe malaria is a potentially fatal condition that requires urgent treatment. In a clinical trial, a sub-group of children treated with rectal artesunate…”
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Repurposing Know-how for Drug Development: Case Studies from the Swiss Tropical and Public Health Institute by Meier, Lukas, Antillon, Marina, Burri, Christian, Chitnis, Nakul, Endriss, Yvette, Keiser, Jennifer, Moore, Sarah, Müller, Pie, Penny, Melissa A, Voss, Till S, Mäser, Pascal, Utzinger, Jürg

“…In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a…”
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Opportunities and challenges for decentralised clinical trials in sub-Saharan Africa: a qualitative study by Nebie, Eric I, Sawadogo, Hélène N, van Eeuwijk, Peter, Signorell, Aita, Reus, Elisabeth, Utzinger, Juerg, Burri, Christian

“…Introduction Digital health has gained traction in research and development, and clinical decision support systems. The COVID-19 pandemic accelerated the…”
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High-Precision Optical Coherence Tomography Navigated Laser Retinopexy for Retinal Breaks by Salzmann, Simon, Wakili, Philip, Al-Nawaiseh, Sami, Považay, Boris, Meier, Christoph, Burri, Christian

“…The prevalent cause of retinal detachment is a full-thickness retinal break and the ingress of fluid into the subretinal space. To prevent progression of the…”
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Acceptability of pre-referral rectal artesunate for severe malaria in children under 5 years by health workers and caregivers in the Democratic Republic of the Congo, Nigeria and Uganda by Awor, Phyllis, Kimera, Joseph, Athieno, Proscovia, Tumukunde, Gloria, Okitawutshu, Jean, Tshefu, Antoinette, Omoluabi, Elizabeth, Signorell, Aita, Brunner, Nina, Kalenga, Jean-Claude, Akano, Babatunde, Ayodeji, Kazeem, Okon, Charles, Yusuf, Ocheche, Delvento, Giulia, Lee, Tristan, Burri, Christian, Lengeler, Christian, Hetzel, Manuel W

“…For children below 6 years with suspected severe malaria attending a health care provider unable to provide parenteral malaria treatment, pre-referral rectal…”
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