Search Results - "Christian Bailly"

Cepharanthine: An update of its mode of action, pharmacological properties and medical applications by Bailly, Christian

“…Cepharanthine (CEP) is a drug used in Japan since the 1950s to treat a number of acute and chronic diseases, including treatment of leukopenia, snake bites,…”
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Contemporary Challenges in the Design of Topoisomerase II Inhibitors for Cancer Chemotherapy by Bailly, Christian

“…Researchers are concentrating on developing chemical families of anticancer drugs known as topoisomerase II posions the limit tumor growth and metastasis…”
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Molecular and cellular basis of the anticancer activity of the prenylated flavonoid icaritin in hepatocellular carcinoma by Bailly, Christian

“…The prenylated flavonoid icaritin (ICT) is currently undergoing phase 3 clinical trial for the treatment of advanced hepatocellular carcinoma (HCC), based on a…”
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Anticancer properties of lamellarins by Bailly, Christian

“…In 1985 the first lamellarins were isolated from a small oceanic sea snail. Today, more than 50 lamellarins have been inventoried and numerous derivatives…”
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The potential value of amlexanox in the treatment of cancer: Molecular targets and therapeutic perspectives by Bailly, Christian

“…[Display omitted] •The small molecule amlexanox (AMX) has been used for decades to treat aphthous ulcers.•AMX has been utilized to treat diabetes and obesity,…”
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The subgroup of 2′-hydroxy-flavonoids: Molecular diversity, mechanism of action, and anticancer properties by Bailly, Christian

“…[Display omitted] •2′-Hydroxyflavonoids represent a minor subgroup of flavonoids.•The natural products 2′-hydroxyflavone and 2′-hydroxyflavanone display…”
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Glycyrrhizin: An alternative drug for the treatment of COVID-19 infection and the associated respiratory syndrome? by Bailly, Christian, Vergoten, Gérard

“…Safe and efficient drugs to combat the current COVID-19 pandemic are urgently needed. In this context, we have analyzed the anti-coronavirus potential of the…”
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Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos-An Overview by Bailly, Christian

“…The dried flower buds of the plant Sieb. et Zucc. have been largely used in traditional Chinese medicine for the treatment of inflammatory diseases. Numerous…”
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Anticancer activities and mechanism of action of the labdane diterpene coronarin D by Bailly, Christian

“…•Coronarin D (CRD) is a labdane diterpene from the plant Hedychium coronarium•CRD inhibits cancer cell proliferation and induces apoptosis of different cell…”
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Ready for a comeback of natural products in oncology by Bailly, Christian

“…Since the late 1990s and the rapid expansion of monoclonal antibodies and synthetic protein kinase inhibitors in oncology, anticancer natural products fell out…”
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Pharmacological Properties and Molecular Targets of Alisol Triterpenoids from Alismatis Rhizoma by Bailly, Christian

“…More than 100 protostane triterpenoids have been isolated from the dried rhizomes of Alisma species, designated Alismatis rhizoma (AR), commonly used in Asian…”
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Discovery and current developments of isoindolinone-based fungal natural products by Bailly, Christian

“…Most fungi generate secondary metabolites essential to their growth or used as chemical defense systems. They produce a large variety of small molecules,…”
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Anticancer properties and mechanism of action of the fungal nucleoside clitocine and its derivatives by Bailly, Christian

“…Clitocine (CLT) is an atypical nitro-containing pyrimidine nucleoside bearing a ribofuranosyl moiety attached to the exocyclic 4-amino position. It has been…”
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Ruta angustifolia Pers. (Narrow-Leaved Fringed Rue): Pharmacological Properties and Phytochemical Profile by Bailly, Christian

“…The genus in the family includes about 40 species, such as the well-known plants L. (common rue) or L. (fringed rue), but also much lesser-known species such…”
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Discovery and Anticancer Activity of the Plagiochilins from the Liverwort Genus Plagiochila by Bailly, Christian

“…The present analysis retraces the discovery of plagiochilins A-to-W, a series of seco-aromadendrane-type sesquiterpenes isolated from diverse leafy liverworts…”
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Traditional Uses, Pharmacology and Phytochemistry of the Medicinal Plant Flueggea virosa (Roxb. ex Willd.) Royle by Bailly, Christian

“…The white berry bush, officially Flueggea virosa (Roxb. ex Willd.) Royle is a medicinal plant distributed throughout tropical areas and traditionally used in…”
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Fissistigma oldhamii (Hemsl.) Merr.: Ethnomedicinal, Phytochemistry, and Pharmacological Aspects by Bailly, Christian

“…The species (Hemsl.) Merr. (Annonaceae) has long been used as a traditional herbal medicine in China to treat diverse human diseases. Decoctions from the roots…”
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Anticancer Targets and Signaling Pathways Activated by Britannin and Related Pseudoguaianolide Sesquiterpene Lactones by Bailly, Christian

“…Sesquiterpene lactones (SLs) are abundant in plants and display a large spectrum of bioactivities. The compound britannin (BRT), found in different Inula…”
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The implication of the PD-1/PD-L1 checkpoint in chronic periodontitis suggests novel therapeutic opportunities with natural products by Bailly, Christian

“…An analysis of the implication of the PD-1/PD-L1 immune checkpoint in periodontitis is provided with the objective to propose a novel therapeutic approach. An…”
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Toward the use of Boesenbergia rotunda extracts and the chalcone panduratin A to treat periodontitis by Bailly, Christian

“…Novel affordable medications are needed to treat chronic periodontitis, which is one of the most common dental pathologies worldwide. Extracts prepared from…”
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