Search Results - "Christiaans, Sarah C"

Detection of acute traumatic coagulopathy and massive transfusion requirements by means of rotational thromboelastometry: an international prospective validation study by Hagemo, Jostein S, Christiaans, Sarah C, Stanworth, Simon J, Brohi, Karim, Johansson, Pär I, Goslings, J Carel, Naess, Paal A, Gaarder, Christine

“…The purpose of this study was to re-evaluate the findings of a smaller cohort study on the functional definition and characteristics of acute traumatic…”
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Protein C and acute inflammation: a clinical and biological perspective by Christiaans, Sarah C, Wagener, Brant M, Esmon, Charles T, Pittet, Jean Francois

“…The protein C system plays an active role in modulating severe systemic inflammatory processes such as sepsis, trauma, and acute respiratory distress syndrome…”
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Early release of high mobility group box nuclear protein 1 after severe trauma in humans: role of injury severity and tissue hypoperfusion by Cohen, Mitchell J, Brohi, Karim, Calfee, Carolyn S, Rahn, Pamela, Chesebro, Brian B, Christiaans, Sarah C, Carles, Michel, Howard, Marybeth, Pittet, Jean-François

“…High mobility group box nuclear protein 1 (HMGB1) is a DNA nuclear binding protein that has recently been shown to be an early trigger of sterile inflammation…”
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Exoenzyme Y Contributes to End-Organ Dysfunction Caused by Pseudomonas aeruginosa Pneumonia in Critically Ill Patients: An Exploratory Study by Wagener, Brant M, Anjum, Naseem, Christiaans, Sarah C, Banks, Morgan E, Parker, Jordan C, Threet, Adam T, Walker, Rashidra R, Isbell, Kayla D, Moser, Stephen A, Stevens, Troy, Alexeyev, Mikhail F, Audia, Jonathon P, Richter, Wito, Hardy, Kierra S, Saleh, Lina Abou, Morgan, Charity, Pittet, Jean-François

“…is an opportunistic pathogen that causes pneumonia in immunocompromised and intensive care unit (ICU) patients. During host infection, upregulates the type III…”
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THE GLYCOCALYX AND TRAUMA: A REVIEW by Chignalia, Andreia Z, Yetimakman, Feliz, Christiaans, Sarah C, Unal, Sule, Bayrakci, Benan, Wagener, Brant M, Russell, Robert T, Kerby, Jeffrey D, Pittet, Jean-Francois, Dull, Randal O

“…ABSTRACTIn the United States trauma is the leading cause of mortality among those under the age of 45, claiming approximately 192,000 lives each year…”
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Coagulopathy After Severe Pediatric Trauma by Christiaans, Sarah C, Duhachek-Stapelman, Amy L, Russell, Robert T, Lisco, Steven J, Kerby, Jeffrey D, Pittet, Jean-François

“…ABSTRACTTrauma remains the leading cause of morbidity and mortality in the United States among children aged 1 to 21 years. The most common cause of lethality…”
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Early coagulopathy is an independent predictor of mortality in children after severe trauma by Whittaker, Brent, Christiaans, Sarah C, Altice, Jessica L, Chen, Mike K, Bartolucci, Alfred A, Morgan, Charity J, Kerby, Jeffrey D, Pittet, Jean-François

“…To determine whether early coagulopathy affects the mortality associated with severe civilian pediatric trauma, trauma patients younger than 18 years admitted…”
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Histone-Complexed DNA Fragments Levels are Associated with Coagulopathy, Endothelial Cell Damage, and Increased Mortality after Severe Pediatric Trauma by Russell, Robert T, Christiaans, Sarah C, Nice, Tate R, Banks, Morgan, Mortellaro, Vincent E, Morgan, Charity, Duhachek-Stapelman, Amy, Lisco, Steven J, Kerby, Jeffrey D, Wagener, Brant M, Chen, Mike K, Pittet, Jean-François

“…BACKGROUND:The release of damage-associated molecular pattern molecules in the extracellular space secondary to injury has been shown to cause systemic…”
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Angiopoietin-2, Marker and Mediator of Endothelial Activation With Prognostic Significance Early After Trauma? by GANTER, Michael T, COHEN, Mitchell J, BROHI, Karim, CHESEBRO, Brian B, STAUDENMAYER, Kristan L, RAHN, Pamela, CHRISTIAANS, Sarah C, BIR, Natasha D, PITTET, Jean-Francois

“…To measure plasma levels of angiopoietin-1 (Ang-1), angiopoietin-2 (Ang-2), and vascular endothelial growth factor (VEGF) early after trauma and to determine…”
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Abnormalities in admission platelet count and function correlate with survival following severe trauma in children by Russell, Robert T., MD, MPH, Christiaans, Sarah C., MD, Morgan, Charity J., PhD, Nice, Tate R., MD, Minnich, Heather E., BSN, MSPH, Mortellaro, Vincent E., MD, Kerby, Jeffrey D., MD, PhD, FACS, Chen, Mike K., MD, FACS, Pittet, Jean F., MD

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Minimal invasive management of traumatic transection of the vertebral artery by de Castro, Steve MM, Christiaans, Sarah C, van den Berg, Rene, Schep, Niels WL

“…Stab wounds to the neck can be potentially lethal. They are often associated with vascular injury of the carotid artery and jugular vein. Injury of the…”
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Coagulopathy after severe pediatric trauma: A review by Christiaans, Sarah C., Duhachek-Stapelman, Amy L., Russell, Robert T., Lisco, Steven J., Kerby, Jeffrey D., Pittet, Jean-François

“…Trauma remains the leading cause of morbidity and mortality in the United States among children from the age 1 year to 21 years old. The most common cause of…”
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Role of Small GTPases and αvβ5 Integrin in Pseudomonas aeruginosa –Induced Increase in Lung Endothelial Permeability by Ganter, Michael T., Roux, Jérémie, Su, George, Lynch, Susan V., Deutschman, Clifford S., Weiss, Yoram G., Christiaans, Sarah C., Myazawa, Byron, Kipnis, Eric, Wiener-Kronish, Jeanine P., Howard, Marybeth, Pittet, Jean-François

“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe pneumonia associated with airspace flooding with protein-rich edema in critically ill…”
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Role of Small GTPases and {alpha}v{beta}5 Integrin in Pseudomonas aeruginosa-Induced Increase in Lung Endothelial Permeability by Ganter, Michael T, Roux, Jeremie, Su, George, Lynch, Susan V, Deutschman, Clifford S, Weiss, Yoram G, Christiaans, Sarah C, Myazawa, Byron, Kipnis, Eric, Wiener-Kronish, Jeanine P, Howard, Marybeth, Pittet, Jean-Francois

“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe pneumonia associated with airspace flooding with protein-rich edema in critically ill…”
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Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability by Ganter, Michael T, Roux, Jérémie, Su, George, Lynch, Susan V, Deutschman, Clifford S, Weiss, Yoram G, Christiaans, Sarah C, Myazawa, Byron, Kipnis, Eric, Wiener-Kronish, Jeanine P, Howard, Marybeth, Pittet, Jean-François

“…Pseudomonas aeruginosa is an opportunistic pathogen that can cause severe pneumonia associated with airspace flooding with protein-rich edema in critically ill…”
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Transfusion policy in trauma involving massive blood loss by Saltzherr, Teun Peter, Christiaans, Sarah C, Henny, C Pieter, Levi, Marcel M, Goslings, J Carel

“…Severe haemorrhage is a significant cause of death in trauma patients. In the case of massive blood loss a combination of coagulation defects, acidosis and…”
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