Search Results - "Christi, Abraham"

Base-edited CAR T cells for combinational therapy against T cell malignancies by Georgiadis, Christos, Rasaiyaah, Jane, Gkazi, Soragia Athina, Preece, Roland, Etuk, Aniekan, Christi, Abraham, Qasim, Waseem

“…Targeting T cell malignancies using chimeric antigen receptor (CAR) T cells is hindered by ‘T v T’ fratricide against shared antigens such as CD3 and CD7. Base…”
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‘Mini’ U6 Pol III promoter exhibits nucleosome redundancy and supports multiplexed coupling of CRISPR/Cas9 effects by Preece, Roland, Georgiadis, Christos, Gkazi, Soragia Athina, Etuk, Aniekan, Christi, Abraham, Qasim, Waseem

“…RNA polymerase III (Pol III) promoters express short non-coding RNAs and have been adopted for expression of microRNA, interference RNA, and CRISPR single…”
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Universal' Fratricide-Resistant CAR T Cells Against T Cell Leukemia Generated By Coupled & Uncoupled Deamination Mediated Base Editing by Georgiadis, Christos, Rasaiyaah, Jane, Gkazi, Soragia Athina, Preece, Roland, Etuk, Annie, Christi, Abraham, Qasim, Waseem

“…Chimeric antigen receptor (CAR) T cell approaches to target T cell malignancies have been hampered by the fundamental issue of ‘T v T’ fratricide when T…”
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