Search Results - "Christenson Wick, Zoe"
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Specificity, Versatility, and Continual Development: The Power of Optogenetics for Epilepsy Research
Published in Frontiers in cellular neuroscience (14-06-2018)“…Optogenetics is a powerful and rapidly expanding set of techniques that use genetically encoded light sensitive proteins such as opsins. Through the selective…”
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Dissociable contributions of the amygdala and ventral hippocampus to stress-induced changes in defensive behavior
Published in Cell reports (Cambridge) (26-11-2024)“…Stress can have profound consequences on mental health. While much is known about the neural circuits supporting associative memories of stressful events, our…”
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3
Novel long-range inhibitory nNOS-expressing hippocampal cells
Published in eLife (14-10-2019)“…The hippocampus, a brain region that is important for spatial navigation and episodic memory, benefits from a rich diversity of neuronal cell-types. Through…”
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4
Axonal sprouting in commissurally projecting parvalbumin‐expressing interneurons
Published in Journal of neuroscience research (01-12-2017)“…Previous research has shown that in vivo on‐demand optogenetic stimulation of inhibitory interneurons expressing parvalbumin (PV) is sufficient to suppress…”
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To Stop the Seizure, You Must Become the Seizure: Closed-Loop Stimulation Phase Locked to Seizure Waves Disrupts Kindled Seizures While Open-Loop Stimulation Fails
Published in Epilepsy currents (01-07-2021)“…Closed-Loop Stimulation of the Medial Septum Terminates Epileptic Seizures Takeuchi Y, Harangozó M, Pedraza L, Földi T, Kozák G, Li Q, Berényi A. Brain…”
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Seizing Sequencing Data to Consider Cell and Circuit Complexity
Published in Epilepsy currents (01-03-2019)“…Classes and Continua of Hippocampal CA1 Inhibitory Neurons Revealed by Single-Cell Transcriptomics Harris K, Hochgerner H, Skene NG, et al. PLoS Biol…”
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Long-Range Inhibition in the Healthy and Epileptic Hippocampus
Published 01-01-2019“…There are many sources of inhibition and excitation that are carefully, and crucially, balanced within the brain. When this balance is off, pathological…”
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Dissertation -
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Selective loss of the GABAAα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype
Published in Journal of neurophysiology (01-10-2020)“…Previously, an essential tremor-like phenotype has been noted in animals with a global knockout of the GABA Aα1 subunit. Given the hypothesized role of the…”
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Journal Article -
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Progressive Excitability Changes in the Medial Entorhinal Cortex in the 3xTg Mouse Model of Alzheimer's Disease Pathology
Published in The Journal of neuroscience (01-11-2023)“…Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by memory loss and progressive cognitive impairments. In mouse models of AD…”
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Chronotate: An open-source tool for manual timestamping and quantification of animal behavior
Published in Neuroscience letters (25-09-2023)“…•Chronotate provides an easy-to-use interface for scoring behavior videos.•Time-stamped outputs allow detailed assessment of inter-rater reliability.•Temporal…”
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Journal Article -
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Selective loss of the GABA Aα1 subunit from Purkinje cells is sufficient to induce a tremor phenotype
Published in Journal of neurophysiology (01-10-2020)“…Animals with a global knockout of the GABA Aα1 subunit show a tremor phenotype reminiscent of essential tremor. Here we show that selective knockout of GABA…”
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Journal Article -
12
Offline ensemble co-reactivation links memories across days
Published in Nature (London) (06-11-2024)“…Abstract Memories are encoded in neural ensembles during learning 1–6 and are stabilized by post-learning reactivation 7–17 . Integrating recent experiences…”
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Journal Article