Search Results - "Christenson, W R"

Comparative metabolism of ortho-phenylphenol in mouse, rat and man by BARTELS, M. J., McNETT, D. A., TIMCHALK, C., MENDRALA, A. L., CHRISTENSON, W. R., SANGHA, G. K., BRZAK, K. A., SHABRANG, S. N.

“…1. Ortho-phenylphenol (OPP) was well absorbed in the male B6C3F1 mouse, with 84 and 98% of the administered radioactivity recovered in the 0-48-h urine of…”
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Chronic toxicity and carcinogenicity testing in the Sprague–Dawley rat of a prospective insect repellant (KBR 3023) using the dermal route of exposure by Wahle, Bradley S, Sangha, Ghona K, Lake, Stephen G, Sheets, Larry P, Croutch, Claire, Christenson, Ware R

“…The chronic toxicology and carcinogenic potential of 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine (KBR 3023), a prospective new insect repellent…”
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Urinary physiologic and chemical metabolic effects on the urothelial cytotoxicity and potential DNA adducts of o-phenylphenol in male rats by Smith, R.A. (University of Nebraska Medical Center, Omaha, NE.), Christenson, W.R, Bartels, M.J, Arnold, L.L, St John, M.K, Cano, M, Garland, E.M, Lake, S.G, Wahle, B.S, McNett, D.A, Cohen, S.M

“…ortho-Phenylphenol (OPP), a fungicide and antibacterial agent with food residues, is carcinogenic to rat bladder. The present studies provide information on…”
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Interlaboratory cholinesterase determinations and the effect on the results of statistical evaluation of cholinesterase inhibition by Christenson, W R, Van Goethem, D L, Schroeder, R S, Wahle, B S, Dass, P D, Sangha, G K, Thyssen, J H

“…Cholinesterase activity is often a key parameter in the regulatory assessment of cholinesterase-inhibiting agents such as organophosphorous and carbamate…”
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Carcinogenicity testing in the CD-1 mouse of a prospective insect repellant (KBR 3023) using the dermal route of exposure by Wahle, Bradley S, Sangha, Ghona K, Elcock, Laura E, Sheets, Larry P, Christenson, Ware R

“…The carcinogenic potential of 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine (KBR 3023), a prospective new insect repellant intended for human use,…”
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Extrathyroidally Mediated Changes in Circulating Thyroid Hormone Concentrations in the Male Rat Following Administration of an Experimental Oxyacetamide (FOE 5043) by Christenson, W.R., Becker, B.D., Hoang, H.D., Wahle, B.S., Moore, K.D., Dass, P.D., Lake, S.G., Stuart, B.P., Vangoethem, D.L., Sangha, G.K., Thyssen, J.H.

“…Evidence of increased hepatic metabolizing capacity coupled with reductions in serum thyroxine (T 4) levels were noted in the rat during preliminary toxicity…”
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The effect of combined treatment with potassium dichromate and maleic acid on renal function in the rat by Christenson, W R, Davis, M E, Berndt, W O

“…Subthreshold doses of potassium dichromate (K2Cr2O7) have been shown to enhance or potentiate the nephrotoxic effects of mercuric chloride and citrinin. The…”
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Alterations in the renal function of male and female rats exposed to maleic acid, dichloromaleic acid, and both compounds by Christenson, W R, Davis, M E, Berndt, W O

“…Maleic acid (MA), a known nephrotoxicant in experimental animals, and its chlorinated derivative dichloromaleic acid (DCMA) are present in urban drinking water…”
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Evidence for pteridine regulation of lead-mediated inhibition of uroporphyrinogen and heme formation in rat bone marrow by Christenson, W R, Bestervelt, L L, Piper, W N

“…Uroporphyrin I (URO I) accumulation has been reported in the bone marrow of rats exposed to lead, suggesting a sensitivity of uroporphyrinogen III cosynthase…”
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Tributyl Phosphate Effects on Urine and Bladder Epithelium in Male Sprague–Dawley Rats by Arnold, L.L., Christenson, W.R., Cano, M., St. John, M.K., Wahle, B.S., Cohen, S.M.

“…Tributyl phosphate (TBP) produces tumors of the bladder urothelium in rats at high doses (700 and 3000 ppm), with greater effects in males than in females. TBP…”
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Uroporphyrin accumulation in the bone marrow of rats exposed to lead by Christenson, W R, Reddy, V R, Piper, W N

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Convulsant activity of pyridoxal sulphate and phosphonoethyl pyridoxal: antagonism by GABA and its synthetic analogues by Ebadi, M, Metzler, D E, Christenson, W R

“…Pyridoxal phosphate and its synthetic analogues--pyridoxal 5'-sulphate and the 5-phosphonoethyl analogue of pyridoxal (phosphonoethyl pyridoxal) in doses of…”
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Inhibition of the biosynthesis of uroporphyrinogen and heme in rat liver during obstructive jaundice produced by bile duct ligation by Piper, W N, Tse, J, Sadler, E M, Christenson, W R, Balk, J L, Kohashi, M

“…Altered hepatic microsomal drug metabolism has been reported to occur in afflicted with hyperbilirubinemia. Similarities of the chemical structures of…”
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Evidence of Chemical Stimulation of Hepatic Metabolism by an Experimental Acetanilide (FOE 5043) Indirectly Mediating Reductions in Circulating Thyroid Hormone Levels in the Male Rat by Christenson, W.R., Becker, B.D., Wahle, B.S., Moore, K.D., Dass, P.D., Lake, S.G., Van Goethem, D.L., Stuart, B.P., Sangha, G.K., Thyssen, J.H.

“…N-(4-Fluorophenyl)-N-(1-methylethyl)-2-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy]acetamide (FOE 5043) is a new acetanilide-type herbicide undergoing…”
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Effect in the rat of the interaction of dichloromaleic acid and carbon tetrachloride on renal and hepatic function by Christenson, W R, Davis, M E, Berndt, W O

“…Water purification generates a variety of chlorinated contaminants, one of which is dichloromaleic acid (DCMA). Exposure to this compound is likely to occur in…”
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Extraction and isolation by high performance liquid chromatography of uroporphyrin and coproporphyrin isomers from biological tissues by Reddy, V R, Christenson, W R, Piper, W N

“…A simple, rapid procedure has been developed for extraction of uroporphyrin and coproporphyrin isomers from biological tissues. The recoveries of known…”
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Effect of lead on uroporphyrin and heme content in the bone marrow of rats exposed to nitrous oxide by Piper, W N, Christenson, W R

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Comparative kinetic analysis of cholinesterase methods in rat and human erythrocytes and plasma by Dass, P D, Offutt, D M, Mejia, M B, VanGoethem, D, Christenson, W R, Landes, M M, Stuart, B P, Sangha, G K, Thyssen, J H

“…A kinetic analysis of the substitution of 6,6'-dithiodinicotinic acid (DTNA) for 5,5'-dithiobis-2-nitrobenzoic acid (DTNB) for the determination of rat and…”
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Carcinogenicity testing in the CD-1 mouse of a prospective insect repellent (KBR 3023) using the dermal route of exposure by Wahle, B S, Sangha, G K, Elcock, L E, Sheets, L P, Christenson, W R

“…The carcinogenic potential of 1-(1-methyl-propoxycarbonyl)-2-(2-hydroxyethyl)-piperidine (KBR 3023), a prospective new insect repellent intended for human use,…”
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Tributyl Phosphate Effects on Urine and Bladder Epithelium in Male Sprague-Dawley Rats by Arnold, L. L., Christenson, W. R., Cano, M., John, M. K., Wahle, B. S., Cohen, S. M.

“…Tributyl phosphate (TBP) produces tumors of the bladder urothelium in rats at high doses (700 and 3000 ppm), with greater effects in males than in females. TBP…”
Get full text