Search Results - "Christensen, Trace A."

A Universal Approach to Analyzing Transmission Electron Microscopy with ImageJ by Lam, Jacob, Katti, Prasanna, Biete, Michelle, Mungai, Margaret, AshShareef, Salma, Neikirk, Kit, Garza Lopez, Edgar, Vue, Zer, Christensen, Trace A, Beasley, Heather K, Rodman, Taylor A, Murray, Sandra A, Salisbury, Jeffrey L, Glancy, Brian, Shao, Jianqiang, Pereira, Renata O, Abel, E Dale, Hinton, Jr, Antentor

“…Transmission electron microscopy (TEM) is widely used as an imaging modality to provide high-resolution details of subcellular components within cells and…”
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Differential effect of amyloid beta peptides on mitochondrial axonal trafficking depends on their state of aggregation and binding to the plasma membrane by Zhang, Liang, Trushin, Sergey, Christensen, Trace A., Tripathi, Utkarsh, Hong, Courtney, Geroux, Rachel E., Howell, Kyle G., Poduslo, Joseph F., Trushina, Eugenia

“…Inhibition of mitochondrial axonal trafficking by amyloid beta (Aβ) peptides has been implicated in early pathophysiology of Alzheimer's Disease (AD). Yet, it…”
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White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease by Klosinski, Lauren P., Yao, Jia, Yin, Fei, Fonteh, Alfred N., Harrington, Michael G., Christensen, Trace A., Trushina, Eugenia, Brinton, Roberta Diaz

“…White matter degeneration is a pathological hallmark of neurodegenerative diseases including Alzheimer's. Age remains the greatest risk factor for Alzheimer's…”
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Identification of novel, immune-mediating extracellular vesicles in human lymphatic effluent draining primary cutaneous melanoma by Maus, Rachel L.G., Jakub, James W., Hieken, Tina J., Nevala, Wendy K., Christensen, Trace A., Sutor, Shari L., Flotte, Thomas J., Markovic, Svetomir N.

“…Epithelial tumors including melanoma often first metastasize to regional, sentinel lymph nodes (SLN). Thus, the presence of SLN metastases is a critical…”
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Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira by Garza-Lopez, Edgar, Vue, Zer, Katti, Prasanna, Neikirk, Kit, Biete, Michelle, Lam, Jacob, Beasley, Heather K, Marshall, Andrea G, Rodman, Taylor A, Christensen, Trace A, Salisbury, Jeffrey L, Vang, Larry, Mungai, Margaret, AshShareef, Salma, Murray, Sandra A, Shao, Jianqiang, Streeter, Jennifer, Glancy, Brian, Pereira, Renata O, Abel, E Dale, Hinton, Jr, Antentor

“…High-resolution 3D images of organelles are of paramount importance in cellular biology. Although light microscopy and transmission electron microscopy (TEM)…”
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Partial Inhibition of Complex I Restores Mitochondrial Morphology and Mitochondria-ER Communication in Hippocampus of APP/PS1 Mice by Panes, Jessica, Nguyen, Thi Kim Oanh, Gao, Huanyao, Christensen, Trace A, Stojakovic, Andrea, Trushin, Sergey, Salisbury, Jeffrey L, Fuentealba, Jorge, Trushina, Eugenia

“…Alzheimer's disease (AD) has no cure. Earlier, we showed that partial inhibition of mitochondrial complex I (MCI) with the small molecule CP2 induces an…”
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Shedding of Soluble Epidermal Growth Factor Receptor (sEGFR) Is Mediated by a Metalloprotease/Fibronectin/Integrin Axis and Inhibited by Cetuximab by Wilken, Jason A, Perez-Torres, Marianela, Nieves-Alicea, Rene, Cora, Elsa M, Christensen, Trace A, Baron, Andre T, Maihle, Nita J

“…Soluble epidermal growth factor receptor (sEGFR) is a circulating serum biomarker in cancer patients. Recent studies suggest that baseline serum sEGFR…”
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Correction: Garza-Lopez et al. Protocols for Generating Surfaces and Measuring 3D Organelle Morphology Using Amira. Cells 2022, 11 , 65 by Garza-Lopez, Edgar, Vue, Zer, Katti, Prasanna, Neikirk, Kit, Biete, Michelle, Lam, Jacob, Beasley, Heather K, Marshall, Andrea G, Rodman, Taylor A, Christensen, Trace A, Salisbury, Jeffrey L, Vang, Larry, Mungai, Margaret, AshShareef, Salma, Murray, Sandra A, Shao, Jianqiang, Streeter, Jennifer, Glancy, Brian, Pereira, Renata O, Abel, E Dale, Hinton, Jr, Antentor

“…In the original publication [...]…”
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Altered brain energetics induces mitochondrial fission arrest in Alzheimer’s Disease by Zhang, Liang, Trushin, Sergey, Christensen, Trace A., Bachmeier, Benjamin V., Gateno, Benjamin, Schroeder, Andreas, Yao, Jia, Itoh, Kie, Sesaki, Hiromi, Poon, Wayne W., Gylys, Karen H., Patterson, Emily R., Parisi, Joseph E., Diaz Brinton, Roberta, Salisbury, Jeffrey L., Trushina, Eugenia

“…Altered brain metabolism is associated with progression of Alzheimer’s Disease (AD). Mitochondria respond to bioenergetic changes by continuous fission and…”
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Highly Efficient SARS-CoV-2 Infection of Human Cardiomyocytes: Spike Protein-Mediated Cell Fusion and Its Inhibition by Navaratnarajah, Chanakha K, Pease, David R, Halfmann, Peter J, Taye, Biruhalem, Barkhymer, Alison, Howell, Kyle G, Charlesworth, Jon E, Christensen, Trace A, Kawaoka, Yoshihiro, Cattaneo, Roberto, Schneider, Jay W

“…Severe cardiovascular complications can occur in coronavirus disease of 2019 (COVID-19) patients. Cardiac damage is attributed mostly to the aberrant host…”
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Phage K exposure generates phage-neutralizing activity in a rabbit model-humoral receptiveness may impact efficacy of phage therapy by Herren, Sebastian C, Karau, Melissa J, Koscianski, Christina A, Christensen, Trace A, Granger, Dane, Bergan, Nathanial G, Mandrekar, Jay, Holmes, 3rd, David R, Patel, Robin

“…Phage therapy has not been established in the clinical routine, in part due to uncertainties concerning efficacy and immunogenicity. Here, three rabbits were…”
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Three-dimensional mitochondria reconstructions of murine cardiac muscle changes in size across aging by Vue, Zer, Neikirk, Kit, Vang, Larry, Garza-Lopez, Edgar, Christensen, Trace A, Shao, Jianqiang, Lam, Jacob, Beasley, Heather K, Marshall, Andrea G, Crabtree, Amber, Anudokem, Jr, Josephs, Rodriguez, Benjamin, Kirk, Benjamin, Bacevac, Serif, Barongan, Taylor, Shao, Bryanna, Stephens, Dominique C, Kabugi, Kinuthia, Koh, Ho-Jin, Koh, Alice, Evans, Chantell S, Taylor, Brittany, Reddy, Anilkumar K, Miller-Fleming, Tyne, Actkins, Ky'Era V, Zaganjor, Elma, Daneshgar, Nastaran, Murray, Sandra A, Mobley, Bret C, Damo, Steven M, Gaddy, Jennifer A, Riggs, Blake, Wanjalla, Celestine, Kirabo, Annet, McReynolds, Melanie, Gomez, Jose A, Phillips, Mark A, Exil, Vernat, Dai, Dao-Fu, Hinton, Jr, Antentor

“…With sparse treatment options, cardiac disease remains a significant cause of death among humans. As a person ages, mitochondria breakdown and the heart…”
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Human Melanoma-Derived Extracellular Vesicles Regulate Dendritic Cell Maturation by Maus, Rachel L G, Jakub, James W, Nevala, Wendy K, Christensen, Trace A, Noble-Orcutt, Klara, Sachs, Zohar, Hieken, Tina J, Markovic, Svetomir N

“…Evolution of melanoma from a primary tumor to widespread metastasis is crucially dependent on lymphatic spread. The mechanisms regulating the initial step in…”
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Three-Dimensional Structure of Inner Ear Hair Cell Ribbon Synapses in a Zebrafish Model of Usher Syndrome Type 1B by Riley, Jr, Kenneth C, Koleilat, Alaa, Dugdale, Joseph A, Cooper, Shawna A, Christensen, Trace A, Schimmenti, Lisa A

“…Our understanding of inner ear hair cell ultrastructure has heretofore relied upon two-dimensional imaging; however, serial block-face scanning electron…”
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A Comprehensive Approach to Sample Preparation for Electron Microscopy and the Assessment of Mitochondrial Morphology in Tissue and Cultured Cells by Hinton, Jr, Antentor, Katti, Prasanna, Christensen, Trace A, Mungai, Margaret, Shao, Jianqiang, Zhang, Liang, Trushin, Sergey, Alghanem, Ahmad, Jaspersen, Adam, Geroux, Rachel E, Neikirk, Kit, Biete, Michelle, Lopez, Edgar Garza, Shao, Bryanna, Vue, Zer, Vang, Larry, Beasley, Heather K, Marshall, Andrea G, Stephens, Dominique, Damo, Steven, Ponce, Jessica, Bleck, Christopher K E, Hicsasmaz, Innes, Murray, Sandra A, Edmonds, Ranthony A C, Dajles, Andres, Koo, Young Do, Bacevac, Serif, Salisbury, Jeffrey L, Pereira, Renata O, Glancy, Brian, Trushina, Eugenia, Abel, E Dale

“…Mitochondria respond to metabolic demands of the cell and to incremental damage, in part, through dynamic structural changes that include fission…”
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Prominent Mitochondrial Injury as an Early Event in Heme Protein-Induced Acute Kidney Injury by Singh, Raman Deep, Croatt, Anthony J, Ackerman, Allan W, Grande, Joseph P, Trushina, Eugenia, Salisbury, Jeffrey L, Christensen, Trace A, Adams, Christopher M, Tchkonia, Tamara, Kirkland, James L, Nath, Karl A

“…Mitochondrial injury occurs in and underlies acute kidney injury (AKI) caused by ischemia-reperfusion and other forms of renal injury. However, to date, a…”
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Genetically obese MMTV-TGF-alpha/Lep(ob)Lep(ob) female mice do not develop mammary tumors by Cleary, Margot P, Phillips, Frederick C, Getzin, Susan C, Jacobson, Tina L, Jacobson, Michelle K, Christensen, Trace A, Juneja, Subhash C, Grande, Joseph P, Maihle, Nita J

“…Elevated body weight is a risk factor for postmenopausal breast cancer and is associated with increased incidence of spontaneous and chemically induced mammary…”
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Effect of Moderate Caloric Restriction and/or Weight Cycling on Mammary Tumor Incidence and Latency in MMTV-Neu Female Mice by Pape-Ansorge, Kristin A, Grande, Joseph P, Christensen, Trace A, Maihle, Nita J, Cleary, Margot P

“…Recently, we reported that intermittent caloric restriction-refeeding reduces mammary tumor (MT) incidence and extends latency in murine mammary tumor virus…”
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Membrane localization of v-ErbB is required but not sufficient for ligand-independent transformation by Danielsen, Andrew J, Christensen, Trace A, Lovejoy, Courtney A, Adelsman, Margaret A, Connolly, Denise C, Maihle, Nita J

“…The v-ErbB retroviral oncogene is a transduced, mutated copy of the avian EGF receptor gene, and its expression is sufficient to induce tumor formation in…”
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3D reconstruction of murine mitochondria reveals changes in structure during aging linked to the MICOS complex by Vue, Zer, Garza‐Lopez, Edgar, Neikirk, Kit, Katti, Prasanna, Vang, Larry, Beasley, Heather, Shao, Jianqiang, Marshall, Andrea G., Crabtree, Amber, Murphy, Alexandria C., Jenkins, Brenita C., Prasad, Praveena, Evans, Chantell, Taylor, Brittany, Mungai, Margaret, Killion, Mason, Stephens, Dominique, Christensen, Trace A., Lam, Jacob, Rodriguez, Benjamin, Phillips, Mark A., Daneshgar, Nastaran, Koh, Ho‐Jin, Koh, Alice, Davis, Jamaine, Devine, Nina, Saleem, Mohammad, Scudese, Estevão, Arnold, Kenneth Ryan, Vanessa Chavarin, Valeria, Daniel Robinson, Ryan, Chakraborty, Moumita, Gaddy, Jennifer A., Sweetwyne, Mariya T., Wilson, Genesis, Zaganjor, Elma, Kezos, James, Dondi, Cristiana, Reddy, Anilkumar K., Glancy, Brian, Kirabo, Annet, Quintana, Anita M., Dai, Dao‐Fu, Ocorr, Karen, Murray, Sandra A., Damo, Steven M., Exil, Vernat, Riggs, Blake, Mobley, Bret C., Gomez, Jose A., McReynolds, Melanie R., Hinton, Antentor

“…During aging, muscle gradually undergoes sarcopenia, the loss of function associated with loss of mass, strength, endurance, and oxidative capacity. However,…”
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